Project measure / variable:   GMC03   loco_activity

ID, description, units MPD:55224   loco_activity   total number of squares entered with all four paws in 30 s   [n]  
Data set, strains GMC03   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure observation (SHIRPA)
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  STRAIN COMPARISON PLOT
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GMC03 - total number of squares entered with all four paws in 30 s



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means18.6   n 18.3   n
Median of the strain means19.1   n 20.8   n
SD of the strain means± 10.9 ± 9.64
Coefficient of variation (CV)0.587 0.526
Min–max range of strain means3.25   –   33.1   n 4.25   –   30.4   n
Mean sample size per strain17.5   mice 17.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 27.1653 27.1653 0.5103 0.4756
strain 7 24234.6235 3462.0891 65.0399 < 0.0001
sex:strain 7 472.2995 67.4714 1.2675 0.2667
Residuals 260 13839.8646 53.2302


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.1 5.26   16 1.31 0.523 2.0, 19.0 -0.78
129S1/SvImJ m 11.4 6.05   16 1.51 0.532 2.0, 22.0 -0.72
A/J f 3.25 2.14   16 0.536 0.66 -1.41
A/J m 4.25 2.46   16 0.616 0.58 1.0, 9.0 -1.46
C57BL/6J f 30.3 5.78   16 1.45 0.191 22.0, 41.0 1.07
C57BL/6J m 24.9 5.74   16 1.43 0.231 6.0, 31.0 0.68
CAST/EiJ f 26.5 5.37   19 1.23 0.203 17.0, 35.0 0.72
CAST/EiJ m 26.6 6.19   17 1.5 0.233 15.0, 36.0 0.86
NOD/ShiLtJ f 33.1 6.9   18 1.63 0.209 26.0, 52.0 1.32
NOD/ShiLtJ m 30.4 4.91   16 1.23 0.161 21.0, 41.0 1.25
NZO/HlLtJ f 7.65 5.22   17 1.27 0.683 -1.0
NZO/HlLtJ m 7.41 5.11   17 1.24 0.69 -1.13
PWK/PhJ f 18.8 5.74   20 1.28 0.306 11.0, 32.0 0.02
PWK/PhJ m 18.0 7.25   22 1.55 0.402 2.0, 31.0 -0.03
WSB/EiJ f 19.3 12.4   18 2.93 0.645 4.0, 47.0 0.06
WSB/EiJ m 23.6 16.7   16 4.19 0.711 12.0, 82.0 0.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.0625 1.824 13.6541 6.4709
129S1/SvImJ m 11.375 1.824 14.9666 7.7834
A/J f 3.25 1.824 6.8416 -0.3416
A/J m 4.25 1.824 7.8416 0.6584
C57BL/6J f 30.3125 1.824 33.9041 26.7209
C57BL/6J m 24.875 1.824 28.4666 21.2834
CAST/EiJ f 26.4737 1.6738 29.7696 23.1778
CAST/EiJ m 26.5882 1.7695 30.0726 23.1038
NOD/ShiLtJ f 33.0556 1.7197 36.4418 29.6693
NOD/ShiLtJ m 30.4375 1.824 34.0291 26.8459
NZO/HlLtJ f 7.6471 1.7695 11.1315 4.1626
NZO/HlLtJ m 7.4118 1.7695 10.8962 3.9274
PWK/PhJ f 18.75 1.6314 21.9625 15.5375
PWK/PhJ m 18.0455 1.5555 21.1084 14.9825
WSB/EiJ f 19.2778 1.7197 22.664 15.8915
WSB/EiJ m 23.5625 1.824 27.1541 19.9709


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.7188 1.2897 13.2584 8.1791
A/J both 3.75 1.2897 6.2897 1.2103
C57BL/6J both 27.5937 1.2897 30.1334 25.0541
CAST/EiJ both 26.531 1.2179 28.9291 24.1328
NOD/ShiLtJ both 31.7465 1.2534 34.2147 29.2784
NZO/HlLtJ both 7.5294 1.2512 9.9933 5.0656
PWK/PhJ both 18.3977 1.1271 20.6171 16.1784
WSB/EiJ both 21.4201 1.2534 23.8883 18.952




  GWAS USING LINEAR MIXED MODELS