Project measure / variable:   GMC01   center_distance_1

ID, description, units MPD:55051   center_distance_1   center distance, successive 5 min intervals   [%]  1st 5min  
Data set, strains GMC01   inbred w/CC8   8 strains     sex: both     age: 8-9wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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GMC01 - center distance, successive 5 min intervals 1st 5min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means14.8   % 12.4   %
Median of the strain means14.4   % 14.1   %
SD of the strain means± 11.6 ± 8.93
Coefficient of variation (CV)0.784 0.722
Min–max range of strain means0.206   –   33.8   % 0.406   –   23.7   %
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 521.4614 521.4614 19.8898 < 0.0001
strain 7 24152.0494 3450.2928 131.6024 < 0.0001
sex:strain 7 776.0284 110.8612 4.2285 0.0002
Residuals 259 6790.3475 26.2176


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.01 3.65   16 0.911 0.908 -0.93
129S1/SvImJ m 1.39 1.93   15 0.498 1.38 -1.23
A/J f 0.206 0.749   16 0.187 3.63 -1.26
A/J m 0.406 0.747   16 0.187 1.84 -1.34
C57BL/6J f 22.3 4.99   16 1.25 0.224 12.6, 32.6 0.64
C57BL/6J m 18.1 6.0   16 1.5 0.331 5.5, 29.6 0.64
CAST/EiJ f 16.8 3.81   19 0.874 0.227 10.3, 23.2 0.17
CAST/EiJ m 16.8 4.4   18 1.04 0.262 11.4, 26.0 0.5
NOD/ShiLtJ f 33.8 5.84   18 1.38 0.173 24.2, 46.5 1.63
NOD/ShiLtJ m 23.7 4.89   16 1.22 0.207 16.3, 32.6 1.27
NZO/HlLtJ f 5.02 6.65   17 1.61 1.32 -0.84
NZO/HlLtJ m 6.16 7.54   17 1.83 1.22 -0.7
PWK/PhJ f 12.1 5.91   20 1.32 0.487 4.2, 24.7 -0.23
PWK/PhJ m 11.4 5.07   22 1.08 0.443 5.8, 24.9 -0.11
WSB/EiJ f 24.4 6.55   18 1.54 0.269 13.2, 35.7 0.82
WSB/EiJ m 21.0 6.14   15 1.58 0.293 8.7, 33.6 0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.0125 1.2801 6.5332 1.4918
129S1/SvImJ m 1.3933 1.3221 3.9967 -1.21
A/J f 0.2062 1.2801 2.7269 -2.3144
A/J m 0.4063 1.2801 2.9269 -2.1144
C57BL/6J f 22.2688 1.2801 24.7894 19.7481
C57BL/6J m 18.1188 1.2801 20.6394 15.5981
CAST/EiJ f 16.8211 1.1747 19.1342 14.5079
CAST/EiJ m 16.8389 1.2069 19.2154 14.4624
NOD/ShiLtJ f 33.75 1.2069 36.1265 31.3735
NOD/ShiLtJ m 23.6812 1.2801 26.2019 21.1606
NZO/HlLtJ f 5.0235 1.2419 7.469 2.5781
NZO/HlLtJ m 6.1588 1.2419 8.6042 3.7134
PWK/PhJ f 12.135 1.1449 14.3896 9.8804
PWK/PhJ m 11.4409 1.0917 13.5906 9.2913
WSB/EiJ f 24.3833 1.2069 26.7599 22.0068
WSB/EiJ m 20.98 1.3221 23.5834 18.3766


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.7029 0.9201 4.5148 0.8911
A/J both 0.3062 0.9052 2.0886 -1.4761
C57BL/6J both 20.1938 0.9052 21.9761 18.4114
CAST/EiJ both 16.83 0.8421 18.4882 15.1718
NOD/ShiLtJ both 28.7156 0.8796 30.4478 26.9835
NZO/HlLtJ both 5.5912 0.8781 7.3204 3.862
PWK/PhJ both 11.788 0.791 13.3455 10.2304
WSB/EiJ both 22.6817 0.895 24.4441 20.9192




  GWAS USING LINEAR MIXED MODELS