Project measure / variable:   Gould3   EPM_pct_closed_3

ID, description, units MPD:47322   EPM_pct_closed_3   withdrawal study group, percentage of time in closed arms   [%]  dose: 3 mg  
nicotine study
Data set, strains Gould3   inbred   8 strains     sex: m     age: 8-12wks
Procedure elevated plus maze
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  STRAIN COMPARISON PLOT
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Gould3 - withdrawal study group, percentage of time in closed arms dose: 3 mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means42.1   %
Median of the strain means42.8   %
SD of the strain means± 16.1
Coefficient of variation (CV)0.383
Min–max range of strain means16.6   –   65.8   %
Mean sample size per strain9.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 17821.8622 2545.9803 6.0489 < 0.0001
Residuals 69 29042.2195 420.9017


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 45.2 27.5   10 8.7 0.608 15.5, 89.2 0.19
A/J m 40.4 31.7   10 10.0 0.785 5.78, 87.0 -0.11
BALB/cByJ m 16.6 14.1   10 4.46 0.852 3.54, 48.9 -1.58
C3H/HeJ m 27.8 12.0   9 4.0 0.432 13.5, 48.9 -0.89
C57BL/6J m 57.7 10.4   10 3.29 0.18 39.8, 75.1 0.97
CBA/J m 33.1 29.0   8 10.2 0.874 0.19, 76.2 -0.56
DBA/1J m 50.3 15.4   10 4.87 0.306 33.7, 84.6 0.51
DBA/2J m 65.8 11.9   10 3.76 0.181 41.4, 81.0 1.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 45.246 6.4877 58.1886 32.3034
A/J m 40.351 6.4877 53.2936 27.4084
BALB/cByJ m 16.57 6.4877 29.5126 3.6274
C3H/HeJ m 27.7933 6.8386 41.436 14.1506
C57BL/6J m 57.655 6.4877 70.5976 44.7124
CBA/J m 33.1475 7.2535 47.6178 18.6772
DBA/1J m 50.342 6.4877 63.2846 37.3994
DBA/2J m 65.778 6.4877 78.7206 52.8354




  GWAS USING LINEAR MIXED MODELS