Project measure / variable:   Gould2   cotinine_acu


  STRAIN COMPARISON PLOT
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Gould2 - plasma cotinine acute 0.09mg dose



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means27.5   ng/mL
Median of the strain means25.8   ng/mL
SD of the strain means± 7.13
Coefficient of variation (CV)0.259
Min–max range of strain means20.1   –   42.2   ng/mL
Mean sample size per strain9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 3273.8892 467.6985 9.4491 < 0.0001
Residuals 68 3365.7849 49.4968


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 29.6 12.4   10 3.91 0.418 20.9, 60.0 0.3
A/J m 22.7 4.02   10 1.27 0.177 16.8, 29.0 -0.67
BALB/cByJ m 31.4 4.06   9 1.35 0.13 24.5, 36.9 0.55
C3H/HeJ m 22.4 3.54   10 1.12 0.158 17.7, 30.5 -0.71
C57BL/6J m 23.5 6.72   10 2.13 0.286 9.5, 32.8 -0.56
CBA/J m 20.1 9.27   9 3.09 0.461 7.4, 30.2 -1.04
DBA/1J m 28.0 6.0   9 2.0 0.214 18.4, 36.6 0.07
DBA/2J m 42.2 5.22   9 1.74 0.124 33.0, 46.9 2.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 29.57 2.2248 34.0095 25.1305
A/J m 22.67 2.2248 27.1095 18.2305
BALB/cByJ m 31.3667 2.3451 36.0463 26.687
C3H/HeJ m 22.35 2.2248 26.7895 17.9105
C57BL/6J m 23.51 2.2248 27.9495 19.0705
CBA/J m 20.0889 2.3451 24.7685 15.4092
DBA/1J m 28.0 2.3451 32.6796 23.3204
DBA/2J m 42.2 2.3451 46.8796 37.5204




  GWAS USING LINEAR MIXED MODELS