Project measure / variable:   Threadgill2   APAP_Sulf_300_6

ID, description, units MPD:39644   APAP_Sulf_300_6   serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen   [µg/mL]  6h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen 6h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means8.07   µg/mL
Median of the strain means5.80   µg/mL
SD of the strain means± 5.84
Coefficient of variation (CV)0.724
Min–max range of strain means3.35   –   18.2   µg/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 461.2245 115.3061 17.4503 < 0.0001
Residuals 18 118.9383 6.6077


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 3.35 1.4   5 0.626 0.418 2.55, 5.84 -0.81
C57BL/6J m 7.32 3.33   5 1.49 0.455 3.35, 12.4 -0.13
DBA/2J m 5.8 1.87   5 0.838 0.323 3.15, 7.55 -0.39
LP/J m 18.2 3.3   3 1.91 0.181 14.9, 21.5 1.74
NZW/LacJ m 5.66 2.78   5 1.24 0.491 2.26, 9.51 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 3.346 1.1496 5.7612 0.9308
C57BL/6J m 7.32 1.1496 9.7352 4.9048
DBA/2J m 5.798 1.1496 8.2132 3.3828
LP/J m 18.2333 1.4841 21.3513 15.1153
NZW/LacJ m 5.66 1.1496 8.0752 3.2448




GWAS analysis not available: At least 12 strains are required