Project measure / variable:   Threadgill2   APAP_Sulf_300_3

ID, description, units MPD:39643   APAP_Sulf_300_3   serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen   [µg/mL]  3h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen 3h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means18.7   µg/mL
Median of the strain means16.5   µg/mL
SD of the strain means± 7.26
Coefficient of variation (CV)0.387
Min–max range of strain means12.4   –   31.1   µg/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 887.3074 221.8268 2.7731 0.0589
Residuals 18 1439.8813 79.9934


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 12.4 4.53   5 2.02 0.365 6.86, 18.1 -0.87
C57BL/6J m 16.5 8.11   5 3.63 0.492 3.76, 23.5 -0.31
DBA/2J m 18.5 4.72   5 2.11 0.254 13.4, 23.2 -0.03
LP/J m 31.1 17.5   4 8.73 0.561 14.0, 53.4 1.7
NZW/LacJ m 15.2 5.54   4 2.77 0.365 7.23, 19.6 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 12.412 3.9998 20.8153 4.0087
C57BL/6J m 16.492 3.9998 24.8953 8.0887
DBA/2J m 18.54 3.9998 26.9433 10.1367
LP/J m 31.125 4.472 40.5202 21.7298
NZW/LacJ m 15.1575 4.472 24.5527 5.7623




  GWAS USING LINEAR MIXED MODELS