Project measure / variable:   Threadgill2   APAP_Sulf_300_2

ID, description, units MPD:39642   APAP_Sulf_300_2   serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen   [µg/mL]  2h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen 2h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means20.2   µg/mL
Median of the strain means19.8   µg/mL
SD of the strain means± 6.86
Coefficient of variation (CV)0.340
Min–max range of strain means12.2   –   31.1   µg/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 814.1011 203.5253 5.2301 0.0052
Residuals 19 739.3722 38.9143


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 12.2 2.58   5 1.15 0.211 8.91, 16.1 -1.16
C57BL/6J m 19.8 2.5   5 1.12 0.126 16.0, 22.9 -0.05
DBA/2J m 17.9 6.41   5 2.87 0.359 8.43, 25.8 -0.33
LP/J m 31.1 11.0   4 5.51 0.354 21.1, 43.4 1.59
NZW/LacJ m 19.8 6.32   5 2.82 0.32 8.62, 24.1 -0.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 12.222 2.7898 18.0611 6.3829
C57BL/6J m 19.84 2.7898 25.6791 14.0009
DBA/2J m 17.866 2.7898 23.7051 12.0269
LP/J m 31.075 3.1191 37.6033 24.5467
NZW/LacJ m 19.764 2.7898 25.6031 13.9249




GWAS analysis not available: At least 12 strains are required