Project measure / variable:   Threadgill2   APAP_Sulf_300_1

ID, description, units MPD:39641   APAP_Sulf_300_1   serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen   [µg/mL]  1h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen 1h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means22.6   µg/mL
Median of the strain means22.4   µg/mL
SD of the strain means± 3.43
Coefficient of variation (CV)0.152
Min–max range of strain means17.5   –   26.3   µg/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 225.0338 56.2585 2.4558 0.0809
Residuals 19 435.2595 22.9084


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 17.5 2.34   5 1.05 0.133 15.7, 20.9 -1.48
C57BL/6J m 21.6 4.64   5 2.08 0.215 16.6, 26.8 -0.29
DBA/2J m 22.4 6.38   5 2.85 0.284 15.0, 30.7 -0.05
LP/J m 25.1 5.72   4 2.86 0.228 17.6, 29.6 0.74
NZW/LacJ m 26.3 4.06   5 1.82 0.155 19.9, 31.1 1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 17.54 2.1405 22.0201 13.0599
C57BL/6J m 21.6 2.1405 26.0801 17.1199
DBA/2J m 22.44 2.1405 26.9201 17.9599
LP/J m 25.075 2.3931 30.0839 20.0661
NZW/LacJ m 26.28 2.1405 30.7601 21.7999




GWAS analysis not available: At least 12 strains are required