Project measure / variable:   Threadgill2   APAP_Glc_300_0

ID, description, units MPD:39639   APAP_Glc_300_0   serum acetaminophen glucuronide (APAP-Glc), 300 mg/mL dose acetaminophen   [µg/mL]  baseline  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen glucuronide (APAP-Glc), 300 mg/mL dose acetaminophen baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means14.8   µg/mL
Median of the strain means12.9   µg/mL
SD of the strain means± 4.80
Coefficient of variation (CV)0.325
Min–max range of strain means11.3   –   23.0   µg/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 449.5237 112.3809 2.1999 0.1078
Residuals 19 970.6033 51.0844


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 12.9 5.49   5 2.46 0.425 4.85, 19.9 -0.39
C57BL/6J m 11.8 4.93   5 2.2 0.418 6.52, 19.9 -0.62
DBA/2J m 23.0 10.6   5 4.73 0.46 13.9, 40.2 1.71
LP/J m 11.3 7.03   4 3.52 0.623 6.43, 21.4 -0.73
NZW/LacJ m 14.9 6.26   5 2.8 0.421 8.76, 25.0 0.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 12.93 3.1964 19.6201 6.2399
C57BL/6J m 11.784 3.1964 18.4741 5.0939
DBA/2J m 23.02 3.1964 29.7101 16.3299
LP/J m 11.2975 3.5737 18.7773 3.8177
NZW/LacJ m 14.872 3.1964 21.5621 8.1819




GWAS analysis not available: At least 12 strains are required