Project measure / variable:   Threadgill2   APAP_Sulf_300_0

ID, description, units MPD:39638   APAP_Sulf_300_0   serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen   [µg/mL]  baseline  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen sulfate (APAP-sulfate), 300 mg/mL dose acetaminophen baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means2.49   µg/mL
Median of the strain means2.41   µg/mL
SD of the strain means± 1.24
Coefficient of variation (CV)0.499
Min–max range of strain means0.794   –   4.26   µg/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 30.9219 7.7305 1.1095 0.381
Residuals 19 132.3832 6.9675


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 0.794 0.524   5 0.234 0.66 0.3, 1.64 -1.36
C57BL/6J m 2.41 2.9   5 1.3 1.2 0.14, 7.21 -0.06
DBA/2J m 2.79 2.77   5 1.24 0.992 0.5, 6.47 0.24
LP/J m 2.2 2.68   4 1.34 1.22 0.2, 5.97 -0.23
NZW/LacJ m 4.26 3.37   5 1.51 0.791 0.5, 6.79 1.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 0.794 1.1805 3.2648 0.0
C57BL/6J m 2.414 1.1805 4.8848 0.0
DBA/2J m 2.788 1.1805 5.2588 0.3172
LP/J m 2.2 1.3198 4.9624 0.0
NZW/LacJ m 4.264 1.1805 6.7348 1.7932




GWAS analysis not available: At least 12 strains are required