Project measure / variable:   Harrill1   liver_TG_trt

ID, description, units MPD:39532   liver_TG_trt   hepatic triglycerides (TG)   [mg/dL]  isoniazid  
isoniazid study
Data set, strains Harrill1   inbred   34 strains     sex: f     age: 8-10wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Harrill1 - hepatic triglycerides (TG) isoniazid



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means3.03   mg/dL
Median of the strain means2.49   mg/dL
SD of the strain means± 1.51
Coefficient of variation (CV)0.498
Min–max range of strain means1.20   –   6.75   mg/dL
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 297.0845 9.0026 5.7721 < 0.0001
Residuals 99 154.4064 1.5597


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.23 0.703   4 0.352 0.217 2.26, 3.94 0.13
A/J f 4.38 1.3   4 0.65 0.297 3.13, 6.07 0.9
AKR/J f 2.56 0.46   4 0.23 0.18 2.23, 3.23 -0.31
BALB/cJ f 1.76 0.586   4 0.293 0.333 1.24, 2.47 -0.84
BTBR T+ Itpr3tf/J f 1.77 0.889   4 0.444 0.504 0.53, 2.65 -0.83
BUB/BnJ f 6.75 0.686   4 0.343 0.102 6.2, 7.7 2.47
C3H/HeJ f 1.25 1.1   4 0.551 0.88 0.34, 2.81 -1.18
C57BL/6J f 1.34 0.386   4 0.193 0.288 0.88, 1.82 -1.12
C57BLKS/J f 2.26 0.466   4 0.233 0.206 1.64, 2.75 -0.51
C57BR/cdJ f 1.92 1.83   4 0.913 0.952 0.53, 4.44 -0.73
C58/J f 1.2 0.881   4 0.441 0.737 0.33, 2.06 -1.21
CBA/J f 1.66 1.21   4 0.603 0.727 0.43, 2.93 -0.91
CE/J f 5.87 0.613   4 0.306 0.104 5.39, 6.76 1.88
DBA/2J f 2.15 0.261   4 0.13 0.121 1.77, 2.34 -0.58
FVB/NJ f 2.02 1.17   4 0.585 0.58 0.81, 3.39 -0.67
I/LnJ f 3.83 2.52   4 1.26 0.658 1.48, 6.96 0.53
KK/HlJ f 3.75 1.37   4 0.684 0.365 2.14, 5.39 0.48
LG/J f 4.61 1.58   3 0.915 0.343 2.84, 5.89 1.05
LP/J f 2.38 0.286   4 0.143 0.12 1.99, 2.6 -0.43
MA/MyJ f 4.36 1.55   4 0.775 0.356 3.02, 6.46 0.88
MRL/MpJ f 2.25 0.303   4 0.152 0.135 1.86, 2.6 -0.52
NOD/ShiLtJ f 3.21 0.875   4 0.437 0.273 2.18, 4.09 0.12
NON/ShiLtJ f 1.39 2.01   4 1.01 1.45 0.19, 4.4 -1.09
NOR/LtJ f 2.16 0.418   4 0.209 0.194 1.6, 2.57 -0.58
NZW/LacJ f 2.24 0.312   4 0.156 0.139 1.92, 2.63 -0.52
P/J f 5.96 1.96   4 0.981 0.329 3.87, 8.08 1.94
PL/J f 1.52 0.491   4 0.246 0.324 0.89, 2.04 -1.0
PWK/PhJ f 3.8 0.881   3 0.509 0.232 3.17, 4.81 0.51
RIIIS/J f 2.62 2.48   4 1.24 0.949 0.61, 6.16 -0.27
SEA/GnJ f 5.08 1.61   4 0.803 0.316 3.91, 7.46 1.36
SJL/J f 2.45 0.236   4 0.118 0.0965 2.24, 2.72 -0.38
SM/J f 5.47 1.28   4 0.638 0.233 3.71, 6.76 1.62
SWR/J f 3.22 1.43   4 0.717 0.446 1.83, 4.78 0.13
WSB/EiJ f 2.53 2.4   3 1.39 0.948 0.22, 5.01 -0.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.2325 0.6244 4.4715 1.9935
A/J f 4.38 0.6244 5.619 3.141
AKR/J f 2.5575 0.6244 3.7965 1.3185
BALB/cJ f 1.76 0.6244 2.999 0.521
BTBR T+ Itpr3tf/J f 1.765 0.6244 3.004 0.526
BUB/BnJ f 6.755 0.6244 7.994 5.516
C3H/HeJ f 1.2525 0.6244 2.4915 0.0135
C57BL/6J f 1.3375 0.6244 2.5765 0.0985
C57BLKS/J f 2.2575 0.6244 3.4965 1.0185
C57BR/cdJ f 1.9175 0.6244 3.1565 0.6785
C58/J f 1.195 0.6244 2.434 0.0
CBA/J f 1.6575 0.6244 2.8965 0.4185
CE/J f 5.8675 0.6244 7.1065 4.6285
DBA/2J f 2.155 0.6244 3.394 0.916
FVB/NJ f 2.0175 0.6244 3.2565 0.7785
I/LnJ f 3.835 0.6244 5.074 2.596
KK/HlJ f 3.745 0.6244 4.984 2.506
LG/J f 4.6133 0.721 6.044 3.1826
LP/J f 2.385 0.6244 3.624 1.146
MA/MyJ f 4.3575 0.6244 5.5965 3.1185
MRL/MpJ f 2.245 0.6244 3.484 1.006
NOD/ShiLtJ f 3.205 0.6244 4.444 1.966
NON/ShiLtJ f 1.39 0.6244 2.629 0.151
NOR/LtJ f 2.16 0.6244 3.399 0.921
NZW/LacJ f 2.2375 0.6244 3.4765 0.9985
P/J f 5.9575 0.6244 7.1965 4.7185
PL/J f 1.5175 0.6244 2.7565 0.2785
PWK/PhJ f 3.8033 0.721 5.234 2.3726
RIIIS/J f 2.6175 0.6244 3.8565 1.3785
SEA/GnJ f 5.085 0.6244 6.324 3.846
SJL/J f 2.4475 0.6244 3.6865 1.2085
SM/J f 5.47 0.6244 6.709 4.231
SWR/J f 3.215 0.6244 4.454 1.976
WSB/EiJ f 2.53 0.721 3.9607 1.0993




  GWAS USING LINEAR MIXED MODELS