Project measure / variable:   Harrill1   liver_CHOL_ctrl

ID, description, units MPD:39526   liver_CHOL_ctrl   hepatic cholesterol (CHOL)   [mg/dL]  control   measure
isoniazid study
Data set, strains Harrill1   inbred   34 strains     sex: f     age: 8-10wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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Harrill1 - hepatic cholesterol (CHOL) control



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means23.4   mg/dL
Median of the strain means21.5   mg/dL
SD of the strain means± 7.55
Coefficient of variation (CV)0.323
Min–max range of strain means13.8   –   53.0   mg/dL
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 7537.5588 228.4109 4.1213 < 0.0001
Residuals 102 5653.0 55.4216


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 17.8 5.19   4 2.59 0.292 14.0, 25.0 -0.74
A/J f 33.2 4.27   4 2.14 0.128 27.0, 36.0 1.3
AKR/J f 19.0 8.76   4 4.38 0.461 10.0, 31.0 -0.58
BALB/cJ f 17.8 2.99   4 1.49 0.168 15.0, 22.0 -0.74
BTBR T+ Itpr3tf/J f 23.5 9.68   4 4.84 0.412 10.0, 31.0 0.01
BUB/BnJ f 19.8 10.0   4 5.02 0.509 7.0, 30.0 -0.48
C3H/HeJ f 15.0 2.16   4 1.08 0.144 13.0, 18.0 -1.11
C57BL/6J f 23.8 4.57   4 2.29 0.193 19.0, 30.0 0.05
C57BLKS/J f 30.0 6.98   4 3.49 0.233 22.0, 38.0 0.87
C57BR/cdJ f 21.2 9.57   4 4.78 0.45 12.0, 30.0 -0.29
C58/J f 29.0 10.7   4 5.34 0.368 13.0, 35.0 0.74
CBA/J f 19.5 5.26   4 2.63 0.27 12.0, 24.0 -0.52
CE/J f 28.0 2.94   4 1.47 0.105 25.0, 31.0 0.61
DBA/2J f 20.2 3.59   4 1.8 0.177 17.0, 25.0 -0.42
FVB/NJ f 26.0 5.66   4 2.83 0.218 22.0, 34.0 0.34
I/LnJ f 14.8 2.87   4 1.44 0.195 11.0, 17.0 -1.14
KK/HlJ f 28.2 3.1   4 1.55 0.11 24.0, 31.0 0.64
LG/J f 22.2 4.27   4 2.14 0.192 16.0, 25.0 -0.16
LP/J f 18.5 1.29   4 0.645 0.0698 17.0, 20.0 -0.65
MA/MyJ f 53.0 15.4   4 7.71 0.291 31.0, 67.0 3.92
MRL/MpJ f 21.0 2.45   4 1.22 0.117 18.0, 23.0 -0.32
NOD/ShiLtJ f 26.8 5.68   4 2.84 0.212 21.0, 33.0 0.45
NON/ShiLtJ f 17.8 5.38   4 2.69 0.303 11.0, 23.0 -0.74
NOR/LtJ f 17.0 2.45   4 1.22 0.144 15.0, 20.0 -0.85
NZW/LacJ f 21.8 2.36   4 1.18 0.109 20.0, 25.0 -0.21
P/J f 19.2 0.957   4 0.479 0.0497 18.0, 20.0 -0.56
PL/J f 23.0 9.83   4 4.92 0.427 11.0, 35.0 -0.05
PWK/PhJ f 33.2 13.3   4 6.66 0.401 24.0, 53.0 1.3
RIIIS/J f 13.8 5.25   4 2.63 0.382 9.0, 21.0 -1.27
SEA/GnJ f 21.8 9.43   4 4.71 0.434 9.0, 31.0 -0.21
SJL/J f 21.2 5.44   4 2.72 0.256 14.0, 27.0 -0.29
SM/J f 24.5 6.76   4 3.38 0.276 17.0, 33.0 0.15
SWR/J f 18.2 3.5   4 1.75 0.192 14.0, 22.0 -0.69
WSB/EiJ f 35.8 19.1   4 9.54 0.534 9.0, 54.0 1.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 17.75 3.7223 25.1331 10.3669
A/J f 33.25 3.7223 40.6331 25.8669
AKR/J f 19.0 3.7223 26.3831 11.6169
BALB/cJ f 17.75 3.7223 25.1331 10.3669
BTBR T+ Itpr3tf/J f 23.5 3.7223 30.8831 16.1169
BUB/BnJ f 19.75 3.7223 27.1331 12.3669
C3H/HeJ f 15.0 3.7223 22.3831 7.6169
C57BL/6J f 23.75 3.7223 31.1331 16.3669
C57BLKS/J f 30.0 3.7223 37.3831 22.6169
C57BR/cdJ f 21.25 3.7223 28.6331 13.8669
C58/J f 29.0 3.7223 36.3831 21.6169
CBA/J f 19.5 3.7223 26.8831 12.1169
CE/J f 28.0 3.7223 35.3831 20.6169
DBA/2J f 20.25 3.7223 27.6331 12.8669
FVB/NJ f 26.0 3.7223 33.3831 18.6169
I/LnJ f 14.75 3.7223 22.1331 7.3669
KK/HlJ f 28.25 3.7223 35.6331 20.8669
LG/J f 22.25 3.7223 29.6331 14.8669
LP/J f 18.5 3.7223 25.8831 11.1169
MA/MyJ f 53.0 3.7223 60.3831 45.6169
MRL/MpJ f 21.0 3.7223 28.3831 13.6169
NOD/ShiLtJ f 26.75 3.7223 34.1331 19.3669
NON/ShiLtJ f 17.75 3.7223 25.1331 10.3669
NOR/LtJ f 17.0 3.7223 24.3831 9.6169
NZW/LacJ f 21.75 3.7223 29.1331 14.3669
P/J f 19.25 3.7223 26.6331 11.8669
PL/J f 23.0 3.7223 30.3831 15.6169
PWK/PhJ f 33.25 3.7223 40.6331 25.8669
RIIIS/J f 13.75 3.7223 21.1331 6.3669
SEA/GnJ f 21.75 3.7223 29.1331 14.3669
SJL/J f 21.25 3.7223 28.6331 13.8669
SM/J f 24.5 3.7223 31.8831 17.1169
SWR/J f 18.25 3.7223 25.6331 10.8669
WSB/EiJ f 35.75 3.7223 43.1331 28.3669




  GWAS USING LINEAR MIXED MODELS