Project measure / variable:   Harrill1   ALT_ctrl

ID, description, units MPD:39521   ALT_ctrl   alanine transaminase (serum ALT)   [IU/L]  control  
isoniazid study
Data set, strains Harrill1   inbred   34 strains     sex: f     age: 8-10wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Harrill1 - alanine transaminase (serum ALT) control



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means24.0   IU/L
Median of the strain means17.9   IU/L
SD of the strain means± 23.2
Coefficient of variation (CV)0.967
Min–max range of strain means8.25   –   138   IU/L
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 70744.8335 2143.7828 1.064 0.3947
Residuals 101 203491.7342 2014.7696


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 138.0 251.0   4 125.0 1.82 11.7, 514.0 4.92
A/J f 27.0 11.2   4 5.61 0.416 20.8, 43.8 0.13
AKR/J f 18.5 3.42   4 1.71 0.185 14.0, 22.0 -0.24
BALB/cJ f 51.0 38.2   4 19.1 0.75 14.0, 84.0 1.17
BTBR T+ Itpr3tf/J f 20.2 12.0   4 5.99 0.592 13.0, 38.0 -0.16
BUB/BnJ f 10.9 4.91   4 2.46 0.452 6.8, 18.0 -0.56
C3H/HeJ f 15.0 4.76   4 2.38 0.317 10.0, 20.0 -0.39
C57BL/6J f 21.2 8.22   4 4.11 0.387 14.0, 33.0 -0.12
C57BLKS/J f 20.5 8.5   4 4.25 0.415 12.0, 32.0 -0.15
C57BR/cdJ f 16.4 7.91   4 3.95 0.482 9.5, 27.6 -0.33
C58/J f 17.2 4.41   4 2.21 0.257 12.6, 22.5 -0.29
CBA/J f 17.0 3.83   4 1.91 0.225 12.0, 20.0 -0.3
CE/J f 14.8 4.31   4 2.15 0.291 8.7, 18.8 -0.4
DBA/2J f 16.0 5.16   4 2.58 0.323 10.0, 22.0 -0.34
FVB/NJ f 28.5 9.29   4 4.65 0.326 20.0, 40.0 0.2
I/LnJ f 16.5 5.6   3 3.23 0.34 12.7, 22.9 -0.32
KK/HlJ f 12.9 0.622   4 0.311 0.0482 12.4, 13.8 -0.48
LG/J f 16.8 3.73   4 1.86 0.221 12.3, 21.2 -0.31
LP/J f 24.8 6.7   4 3.35 0.271 18.0, 34.0 0.04
MA/MyJ f 68.5 43.5   4 21.7 0.635 26.0, 123.0 1.92
MRL/MpJ f 26.5 7.23   4 3.62 0.273 18.0, 33.0 0.11
NOD/ShiLtJ f 8.5 1.41   4 0.704 0.166 7.1, 10.4 -0.67
NON/ShiLtJ f 8.25 2.75   4 1.38 0.333 4.6, 10.7 -0.68
NOR/LtJ f 19.8 12.2   4 6.12 0.619 12.0, 38.0 -0.18
NZW/LacJ f 16.5 1.91   4 0.957 0.116 15.0, 19.0 -0.32
P/J f 19.9 4.63   4 2.32 0.233 13.9, 24.5 -0.18
PL/J f 21.8 5.8   4 2.9 0.266 14.0, 28.0 -0.09
PWK/PhJ f 16.1 16.0   4 7.98 0.993 4.5, 39.3 -0.34
RIIIS/J f 15.1 12.8   4 6.38 0.845 4.0, 33.5 -0.38
SEA/GnJ f 11.3 2.69   4 1.34 0.237 8.4, 14.7 -0.55
SJL/J f 26.2 6.13   4 3.07 0.234 19.0, 34.0 0.1
SM/J f 9.6 3.01   4 1.5 0.313 7.2, 14.0 -0.62
SWR/J f 18.5 2.95   4 1.48 0.159 16.6, 22.9 -0.24
WSB/EiJ f 25.3 9.1   4 4.55 0.36 12.6, 34.0 0.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 137.9 22.4431 182.4211 93.3789
A/J f 26.975 22.4431 71.4961 0.0
AKR/J f 18.5 22.4431 63.0211 0.0
BALB/cJ f 51.0 22.4431 95.5211 6.4789
BTBR T+ Itpr3tf/J f 20.25 22.4431 64.7711 0.0
BUB/BnJ f 10.875 22.4431 55.3961 0.0
C3H/HeJ f 15.0 22.4431 59.5211 0.0
C57BL/6J f 21.25 22.4431 65.7711 0.0
C57BLKS/J f 20.5 22.4431 65.0211 0.0
C57BR/cdJ f 16.425 22.4431 60.9461 0.0
C58/J f 17.175 22.4431 61.6961 0.0
CBA/J f 17.0 22.4431 61.5211 0.0
CE/J f 14.8 22.4431 59.3211 0.0
DBA/2J f 16.0 22.4431 60.5211 0.0
FVB/NJ f 28.5 22.4431 73.0211 0.0
I/LnJ f 16.4667 25.9151 67.8752 0.0
KK/HlJ f 12.9 22.4431 57.4211 0.0
LG/J f 16.825 22.4431 61.3461 0.0
LP/J f 24.75 22.4431 69.2711 0.0
MA/MyJ f 68.5 22.4431 113.0211 23.9789
MRL/MpJ f 26.5 22.4431 71.0211 0.0
NOD/ShiLtJ f 8.5 22.4431 53.0211 0.0
NON/ShiLtJ f 8.25 22.4431 52.7711 0.0
NOR/LtJ f 19.75 22.4431 64.2711 0.0
NZW/LacJ f 16.5 22.4431 61.0211 0.0
P/J f 19.85 22.4431 64.3711 0.0
PL/J f 21.75 22.4431 66.2711 0.0
PWK/PhJ f 16.075 22.4431 60.5961 0.0
RIIIS/J f 15.1 22.4431 59.6211 0.0
SEA/GnJ f 11.325 22.4431 55.8461 0.0
SJL/J f 26.25 22.4431 70.7711 0.0
SM/J f 9.6 22.4431 54.1211 0.0
SWR/J f 18.525 22.4431 63.0461 0.0
WSB/EiJ f 25.275 22.4431 69.7961 0.0




  GWAS USING LINEAR MIXED MODELS