Project measure / variable:   Bopp1   luciferase_spleen

ID, description, units MPD:36405   luciferase_spleen   percentage of parasites in spleen relative to all organs tested   [%]  
Plasmodium berghei study
Data set, strains Bopp1   inbred   28 strains     sex: both     age: 8-12wks
Procedure health assessment
Ontology mappings

  STRAIN COMPARISON PLOT
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Bopp1 - percentage of parasites in spleen relative to all organs tested



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested26 strains25 strains
Mean of the strain means16.0   % 17.1   %
Median of the strain means13.4   % 17.0   %
SD of the strain means± 8.35 ± 10.4
Coefficient of variation (CV)0.521 0.606
Min–max range of strain means4.86   –   36.4   % 4.46   –   46.1   %
Mean sample size per strain1.9   mice 1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 61.6386 61.6386 1.7832 0.1912
strain 13 4009.2901 308.4069 8.922 < 0.0001
sex:strain 13 906.0523 69.6963 2.0163 0.0529
Residuals 32 1106.146 34.5671


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.0 3.44   2   2.43 0.171 17.6, 22.5 0.48
129S1/SvImJ m 19.5 9.3   2   6.58 0.476 12.9, 26.1 0.23
A/J f 9.03 1.8   2   1.28 0.2 7.75, 10.3 -0.84
A/J m 19.6 13.1   2   9.23 0.668 10.3, 28.8 0.24
AKR/J f 9.96 2.51   4 1.26 0.252 8.18, 13.7 -0.73
AKR/J m 11.0 3.79   3 2.19 0.344 7.52, 15.1 -0.59
BTBR T+ Itpr3tf/J f 5.03 2.85   2   2.01 0.567 3.01, 7.04 -1.32
BTBR T+ Itpr3tf/J m 7.18 3.41   2   2.41 0.475 4.77, 9.59 -0.96
BUB/BnJ f 10.5 0.58   2   0.41 0.0553 10.1, 10.9 -0.66
BUB/BnJ m 9.79 0.686   2   0.485 0.07 9.31, 10.3 -0.71
C3H/HeJ f 36.4 5.78   2   4.09 0.159 32.4, 40.5 2.44
C3H/HeJ m 29.4 7.34   2   5.19 0.25 24.2, 34.5 1.18
C57BL/6J m 23.3 8.41   2   5.95 0.36 17.4, 29.3 0.6
C57BR/cdJ f 17.9 2.18   2   1.54 0.122 16.3, 19.4 0.22
C57BR/cdJ m 5.45 0.955   2   0.675 0.175 4.77, 6.12 -1.13
C58/J f 12.3 1.14   2   0.805 0.0924 11.5, 13.1 -0.45
C58/J m 6.09 2.64   2   1.87 0.434 4.22, 7.96 -1.06
CBA/J f 15.5 0.0   1   0.0 0.0 15.5, 15.5 -0.06
CBA/J m 8.62 5.78   2   4.08 0.671 4.53, 12.7 -0.82
CZECHII/EiJ f 28.1 0.0   1   0.0 0.0 28.1, 28.1 1.45
CZECHII/EiJ m 25.4 1.12   2   0.79 0.0439 24.7, 26.2 0.8
DBA/2J f 10.3 5.63   3 3.25 0.544 4.62, 15.9 -0.69
DBA/2J m 4.46 0.0   1   0.0 0.0 4.46, 4.46 -1.22
I/LnJ f 36.4 8.12   2   5.75 0.223 30.6, 42.1 2.44
I/LnJ m 38.4 0.0   1   0.0 0.0 38.4, 38.4 2.05
KK/HlJ f 16.4 0.283   2   0.2 0.0172 16.2, 16.6 0.04
KK/HlJ m 18.5 0.997   2   0.705 0.054 17.8, 19.2 0.13
LG/J f 12.4 7.52   2   5.32 0.604 7.13, 17.8 -0.43
MRL/MpJ f 4.86 1.98   2   1.4 0.407 3.46, 6.26 -1.34
NOD/ShiLtJ f 11.0 1.56   3 0.9 0.142 9.19, 11.9 -0.6
NOD/ShiLtJ m 9.59 3.35   2   2.37 0.349 7.22, 12.0 -0.73
NON/ShiLtJ f 15.5 0.0   1   0.0 0.0 15.5, 15.5 -0.06
NON/ShiLtJ m 11.6 0.636   2   0.45 0.0551 11.1, 12.0 -0.53
NZO/HlLtJ f 12.7 1.94   2   1.37 0.152 11.4, 14.1 -0.4
NZO/HlLtJ m 17.0 21.4   2   15.1 1.26 1.87, 32.1 -0.01
NZW/LacJ f 13.0 0.0   1   0.0 0.0 13.0, 13.0 -0.36
NZW/LacJ m 24.1 0.0   1   0.0 0.0 24.1, 24.1 0.67
PERA/EiJ f 22.4 3.18   2   2.25 0.142 20.1, 24.6 0.76
P/J f 19.2 17.7   2   12.5 0.921 6.7, 31.8 0.38
P/J m 9.53 0.0   1   0.0 0.0 9.53, 9.53 -0.73
PL/J f 11.4 0.559   2   0.395 0.0488 11.1, 11.8 -0.55
PL/J m 12.4 1.68   2   1.18 0.135 11.2, 13.6 -0.46
RIIIS/J m 18.7 2.71   2   1.91 0.145 16.8, 20.6 0.15
SJL/J f 21.1 1.37   2   0.97 0.0651 20.1, 22.0 0.61
SJL/J m 9.75 0.0   1   0.0 0.0 9.75, 9.75 -0.71
SM/J f 25.1 1.6   2   1.13 0.0637 24.0, 26.2 1.09
SM/J m 46.1 6.99   2   4.94 0.152 41.1, 51.0 2.8
SWR/J f 13.9 4.85   2   3.43 0.348 10.5, 17.4 -0.25
SWR/J m 25.0 10.4   2   7.34 0.415 17.7, 32.3 0.76
WSB/EiJ f 6.35 0.0   1   0.0 0.0 6.35, 6.35 -1.16
WSB/EiJ m 17.5 9.73   3 5.62 0.556 6.35, 24.2 0.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.04 4.1573 28.5082 11.5718
129S1/SvImJ m 19.525 4.1573 27.9932 11.0568
A/J f 9.025 4.1573 17.4932 0.5568
A/J m 19.565 4.1573 28.0332 11.0968
AKR/J f 9.96 2.9397 15.9479 3.9721
AKR/J m 11.0167 3.3945 17.931 4.1024
BTBR T+ Itpr3tf/J f 5.025 4.1573 13.4932 0.0
BTBR T+ Itpr3tf/J m 7.18 4.1573 15.6482 0.0
BUB/BnJ f 10.48 4.1573 18.9482 2.0118
BUB/BnJ m 9.795 4.1573 18.2632 1.3268
C3H/HeJ f 36.44 4.1573 44.9082 27.9718
C3H/HeJ m 29.36 4.1573 37.8282 20.8918
C57BR/cdJ f 17.85 4.1573 26.3182 9.3818
C57BR/cdJ m 5.445 4.1573 13.9132 0.0
C58/J f 12.315 4.1573 20.7832 3.8468
C58/J m 6.09 4.1573 14.5582 0.0
KK/HlJ f 16.42 4.1573 24.8882 7.9518
KK/HlJ m 18.465 4.1573 26.9332 9.9968
NOD/ShiLtJ f 10.99 3.3945 17.9043 4.0757
NOD/ShiLtJ m 9.59 4.1573 18.0582 1.1218
NZO/HlLtJ f 12.74 4.1573 21.2082 4.2718
NZO/HlLtJ m 17.0 4.1573 25.4682 8.5318
PL/J f 11.445 4.1573 19.9132 2.9768
PL/J m 12.375 4.1573 20.8432 3.9068
SM/J f 25.09 4.1573 33.5582 16.6218
SM/J m 46.06 4.1573 54.5282 37.5918
SWR/J f 13.95 4.1573 22.4182 5.4818
SWR/J m 25.0 4.1573 33.4682 16.5318


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 19.7825 2.9397 25.7704 13.7946
A/J both 14.295 2.9397 20.2829 8.3071
AKR/J both 10.4883 2.2452 15.0617 5.915
BTBR T+ Itpr3tf/J both 6.1025 2.9397 12.0904 0.1146
BUB/BnJ both 10.1375 2.9397 16.1254 4.1496
C3H/HeJ both 32.9 2.9397 38.8879 26.9121
C57BR/cdJ both 11.6475 2.9397 17.6354 5.6596
C58/J both 9.2025 2.9397 15.1904 3.2146
KK/HlJ both 17.4425 2.9397 23.4304 11.4546
NOD/ShiLtJ both 10.29 2.6836 15.7562 4.8238
NZO/HlLtJ both 14.87 2.9397 20.8579 8.8821
PL/J both 11.91 2.9397 17.8979 5.9221
SM/J both 35.575 2.9397 41.5629 29.5871
SWR/J both 19.475 2.9397 25.4629 13.4871




  GWAS USING LINEAR MIXED MODELS