Phenotype measure:   Bopp1   body_temp

ID, description, units MPD:36402   body_temp   terminal body temperature, post-infection   [°C]
Plasmodium berghei study
Data set, strains Bopp1   inbred   31 strains     sex: both     age: 8-12wks
Procedure health assessment
Ontology mappings

  STRAIN COMPARISON PLOT
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Bopp1 - terminal body temperature, post-infection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains31 strains
Mean of the strain means30.6   °C 31.0   °C
Median of the strain means30.2   °C 31.4   °C
SD of the strain means± 3.00 ± 3.08
Coefficient of variation (CV)0.0981 0.0994
Min–max range of strain means24.2   –   36.3   °C 25.7   –   36.0   °C
Mean sample size per strain3.6   mice 3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 19.8921 19.8921 2.3961 0.1237
strain 29 1290.563 44.5022 5.3606 < 0.0001
sex:strain 29 438.6925 15.1273 1.8222 0.0108
Residuals 156 1295.0767 8.3018


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 29.0 1.48   4 0.738 0.0509 27.6, 30.6 -0.53
129S1/SvImJ m 29.9 3.03   4 1.51 0.101 27.1, 33.7 -0.36
A/J f 26.9 0.597   4 0.299 0.0222 26.2, 27.6 -1.23
A/J m 26.0 4.45   3 2.57 0.171 21.2, 30.0 -1.62
AKR/J f 35.2 0.964   4 0.482 0.0274 34.2, 36.5 1.53
AKR/J m 34.9 2.39   4 1.19 0.0684 32.6, 38.1 1.27
BALB/cByJ f 32.3 0.572   4 0.286 0.0177 31.7, 33.0 0.57
BALB/cByJ m 32.5 3.33   4 1.67 0.103 29.8, 36.6 0.49
BTBR T+ Itpr3tf/J f 30.2 0.904   4 0.452 0.0299 29.1, 31.3 -0.13
BTBR T+ Itpr3tf/J m 30.6 2.17   4 1.09 0.0711 27.8, 32.9 -0.13
BUB/BnJ f 26.2 2.12   2   1.5 0.081 24.7, 27.7 -1.46
BUB/BnJ m 30.0 1.7   2   1.2 0.0566 28.8, 31.2 -0.32
C3H/HeJ f 28.4 4.84   4 2.42 0.17 23.2, 34.9 -0.73
C3H/HeJ m 28.5 1.65   4 0.823 0.0578 26.3, 30.2 -0.81
C57BL/6J f 32.7 2.82   4 1.41 0.0862 30.3, 36.4 0.7
C57BL/6J m 27.5 2.65   3 1.53 0.0966 24.9, 30.2 -1.14
C57BR/cdJ f 30.6 3.28   4 1.64 0.107 26.5, 34.4 0.0
C57BR/cdJ m 28.9 1.04   4 0.52 0.0361 27.3, 29.5 -0.68
C58/J f 34.2 0.819   4 0.409 0.024 33.3, 34.9 1.2
C58/J m 34.0 0.377   4 0.189 0.0111 33.6, 34.3 0.97
CBA/J f 24.2 1.98   2   1.4 0.0818 22.8, 25.6 -2.13
CBA/J m 30.6 2.25   4 1.13 0.0736 27.6, 32.9 -0.13
CZECHII/EiJ f 36.3 0.0   1   0.0 0.0 36.3, 36.3 1.9
CZECHII/EiJ m 26.3 3.0   3 1.73 0.114 24.5, 29.8 -1.52
DBA/2J f 26.8 1.67   3 0.964 0.0623 25.0, 28.3 -1.26
DBA/2J m 25.9 3.04   4 1.52 0.118 21.4, 28.0 -1.65
FVB/NJ f 29.8 4.35   4 2.17 0.146 24.0, 33.9 -0.26
FVB/NJ m 32.1 4.25   4 2.12 0.132 26.1, 35.8 0.36
I/LnJ f 27.6 5.23   3 3.02 0.19 24.3, 33.6 -1.0
I/LnJ m 31.4 2.2   3 1.27 0.0702 29.2, 33.6 0.13
KK/HlJ f 29.7 1.31   4 0.654 0.0441 28.0, 30.7 -0.3
KK/HlJ m 31.0 4.17   4 2.09 0.135 27.1, 35.8 0.0
LG/J f 33.8 2.9   4 1.45 0.0859 29.6, 36.1 1.07
LG/J m 34.8 1.21   4 0.603 0.0347 33.9, 36.5 1.23
MA/MyJ f 32.4 1.24   3 0.717 0.0384 31.6, 33.8 0.6
MA/MyJ m 31.4 0.557   3 0.321 0.0177 30.9, 32.0 0.13
MRL/MpJ f 31.2 1.87   4 0.937 0.06 28.8, 33.1 0.2
MRL/MpJ m 36.0 2.26   4 1.13 0.0628 33.2, 38.4 1.62
NOD/ShiLtJ f 26.7 1.27   4 0.634 0.0475 25.2, 28.0 -1.3
NOD/ShiLtJ m 32.4 1.56   2   1.1 0.048 31.3, 33.5 0.45
NON/ShiLtJ f 32.7 2.61   3 1.51 0.0797 30.8, 35.7 0.7
NON/ShiLtJ m 31.9 1.35   4 0.676 0.0424 30.5, 33.7 0.29
NZO/HlLtJ f 32.6 0.77   4 0.385 0.0236 31.5, 33.3 0.67
NZO/HlLtJ m 35.3 0.781   3 0.451 0.0221 34.4, 35.8 1.39
NZW/LacJ f 30.6 3.49   4 1.74 0.114 25.7, 33.2 0.0
NZW/LacJ m 31.4 4.79   4 2.4 0.153 24.3, 34.6 0.13
PERA/EiJ f 34.6 1.5   4 0.75 0.0434 32.7, 36.3 1.33
PERA/EiJ m 34.9 1.58   4 0.789 0.0453 32.7, 36.3 1.27
P/J f 29.6 3.32   4 1.66 0.112 26.5, 34.3 -0.33
P/J m 32.1 6.32   4 3.16 0.197 22.7, 36.5 0.36
PL/J f 29.2 0.751   3 0.433 0.0257 28.5, 30.0 -0.46
PL/J m 31.8 1.71   3 0.987 0.0537 30.0, 33.4 0.26
RIIIS/J f 29.5 2.55   2   1.8 0.0863 27.7, 31.3 -0.36
RIIIS/J m 28.1 1.21   4 0.606 0.0432 27.1, 29.7 -0.94
SJL/J f 29.1 4.08   3 2.36 0.14 24.5, 32.2 -0.5
SJL/J m 32.9 1.54   4 0.769 0.0468 31.7, 35.0 0.62
SM/J f 33.1 4.59   4 2.3 0.138 29.0, 37.7 0.84
SM/J m 35.6 3.04   4 1.52 0.0854 31.1, 37.7 1.49
SWR/J f 28.3 2.41   4 1.21 0.0851 26.5, 31.8 -0.76
SWR/J m 25.7 1.38   3 0.797 0.0538 24.1, 26.7 -1.72
WSB/EiJ f 34.9 1.67   3 0.961 0.0478 33.0, 36.2 1.43
WSB/EiJ m 26.6 7.43   4 3.72 0.279 21.9, 37.7 -1.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 29.0 1.4406 31.8457 26.1543
129S1/SvImJ m 29.925 1.4406 32.7707 27.0793
A/J f 26.95 1.4406 29.7957 24.1043
A/J m 25.9667 1.6635 29.2526 22.6808
AKR/J f 35.225 1.4406 38.0707 32.3793
AKR/J m 34.925 1.4406 37.7707 32.0793
BALB/cByJ f 32.3 1.4406 35.1457 29.4543
BALB/cByJ m 32.525 1.4406 35.3707 29.6793
BTBR T+ Itpr3tf/J f 30.25 1.4406 33.0957 27.4043
BTBR T+ Itpr3tf/J m 30.575 1.4406 33.4207 27.7293
BUB/BnJ f 26.2 2.0374 30.2244 22.1756
BUB/BnJ m 30.0 2.0374 34.0244 25.9756
C3H/HeJ f 28.425 1.4406 31.2707 25.5793
C3H/HeJ m 28.475 1.4406 31.3207 25.6293
C57BL/6J f 32.675 1.4406 35.5207 29.8293
C57BL/6J m 27.4667 1.6635 30.7526 24.1808
C57BR/cdJ f 30.625 1.4406 33.4707 27.7793
C57BR/cdJ m 28.85 1.4406 31.6957 26.0043
C58/J f 34.15 1.4406 36.9957 31.3043
C58/J m 33.975 1.4406 36.8207 31.1293
CBA/J f 24.2 2.0374 28.2244 20.1756
CBA/J m 30.575 1.4406 33.4207 27.7293
DBA/2J f 26.8 1.6635 30.0859 23.5141
DBA/2J m 25.85 1.4406 28.6957 23.0043
FVB/NJ f 29.8 1.4406 32.6457 26.9543
FVB/NJ m 32.125 1.4406 34.9707 29.2793
I/LnJ f 27.5667 1.6635 30.8526 24.2808
I/LnJ m 31.3667 1.6635 34.6526 28.0808
KK/HlJ f 29.65 1.4406 32.4957 26.8043
KK/HlJ m 30.975 1.4406 33.8207 28.1293
LG/J f 33.75 1.4406 36.5957 30.9043
LG/J m 34.75 1.4406 37.5957 31.9043
MA/MyJ f 32.3667 1.6635 35.6526 29.0808
MA/MyJ m 31.4 1.6635 34.6859 28.1141
MRL/MpJ f 31.225 1.4406 34.0707 28.3793
MRL/MpJ m 36.05 1.4406 38.8957 33.2043
NOD/ShiLtJ f 26.725 1.4406 29.5707 23.8793
NOD/ShiLtJ m 32.4 2.0374 36.4244 28.3756
NON/ShiLtJ f 32.7333 1.6635 36.0192 29.4474
NON/ShiLtJ m 31.925 1.4406 34.7707 29.0793
NZO/HlLtJ f 32.6 1.4406 35.4457 29.7543
NZO/HlLtJ m 35.3 1.6635 38.5859 32.0141
NZW/LacJ f 30.6 1.4406 33.4457 27.7543
NZW/LacJ m 31.4 1.4406 34.2457 28.5543
PERA/EiJ f 34.575 1.4406 37.4207 31.7293
PERA/EiJ m 34.85 1.4406 37.6957 32.0043
P/J f 29.6 1.4406 32.4457 26.7543
P/J m 32.075 1.4406 34.9207 29.2293
PL/J f 29.2333 1.6635 32.5192 25.9474
PL/J m 31.8 1.6635 35.0859 28.5141
RIIIS/J f 29.5 2.0374 33.5244 25.4756
RIIIS/J m 28.075 1.4406 30.9207 25.2293
SJL/J f 29.1333 1.6635 32.4192 25.8474
SJL/J m 32.9 1.4406 35.7457 30.0543
SM/J f 33.15 1.4406 35.9957 30.3043
SM/J m 35.6 1.4406 38.4457 32.7543
SWR/J f 28.35 1.4406 31.1957 25.5043
SWR/J m 25.6667 1.6635 28.9526 22.3808
WSB/EiJ f 34.8667 1.6635 38.1526 31.5808
WSB/EiJ m 26.625 1.4406 29.4707 23.7793


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 29.4625 1.0187 31.4747 27.4503
A/J both 26.4583 1.1003 28.6318 24.2849
AKR/J both 35.075 1.0187 37.0872 33.0628
BALB/cByJ both 32.4125 1.0187 34.4247 30.4003
BTBR T+ Itpr3tf/J both 30.4125 1.0187 32.4247 28.4003
BUB/BnJ both 28.1 1.4406 30.9457 25.2543
C3H/HeJ both 28.45 1.0187 30.4622 26.4378
C57BL/6J both 30.0708 1.1003 32.2443 27.8974
C57BR/cdJ both 29.7375 1.0187 31.7497 27.7253
C58/J both 34.0625 1.0187 36.0747 32.0503
CBA/J both 27.3875 1.2476 29.8519 24.9231
DBA/2J both 26.325 1.1003 28.4984 24.1516
FVB/NJ both 30.9625 1.0187 32.9747 28.9503
I/LnJ both 29.4667 1.1763 31.7902 27.1432
KK/HlJ both 30.3125 1.0187 32.3247 28.3003
LG/J both 34.25 1.0187 36.2622 32.2378
MA/MyJ both 31.8833 1.1763 34.2068 29.5598
MRL/MpJ both 33.6375 1.0187 35.6497 31.6253
NOD/ShiLtJ both 29.5625 1.2476 32.0269 27.0981
NON/ShiLtJ both 32.3292 1.1003 34.5026 30.1557
NZO/HlLtJ both 33.95 1.1003 36.1234 31.7766
NZW/LacJ both 31.0 1.0187 33.0122 28.9878
PERA/EiJ both 34.7125 1.0187 36.7247 32.7003
P/J both 30.8375 1.0187 32.8497 28.8253
PL/J both 30.5167 1.1763 32.8402 28.1932
RIIIS/J both 28.7875 1.2476 31.2519 26.3231
SJL/J both 31.0167 1.1003 33.1901 28.8432
SM/J both 34.375 1.0187 36.3872 32.3628
SWR/J both 27.0083 1.1003 29.1818 24.8349
WSB/EiJ both 30.7458 1.1003 32.9193 28.5724




  GWAS USING LINEAR MIXED MODELS