Project measure / variable:   Rusyn2   DCV_glutathione24_tce

ID, description, units MPD:36197   DCV_glutathione24_tce   DCV glutathione (serum DCVG x 10-3)   [nmol/mL]  24h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   11 strains     sex: m     age: 7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn2 - DCV glutathione (serum DCVG x 10-3) 24h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested11 strains
Mean of the strain means0.119   nmol/mL
Median of the strain means0.0630   nmol/mL
SD of the strain means± 0.161
Coefficient of variation (CV)1.36
Min–max range of strain means0.0219   –   0.590   nmol/mL
Mean sample size per strain1.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 3 0.0056 0.0019 2052.5729 < 0.0001
Residuals 7 0.0 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.108 0.0   2   0.0 0.0 0.108, 0.108 -0.07
B6C3F1/J m 0.59 0.0   1   0.0 0.0 0.59, 0.59 2.93
BALB/cByJ m 0.0615 0.0   3 0.0 0.0 0.0615, 0.0615 -0.35
BTBR T+ Itpr3tf/J m 0.063 0.0   1   0.0 0.0 0.063, 0.063 -0.34
C3H/HeJ m 0.0815 0.00179   3 0.00103 0.022 0.0794, 0.0825 -0.23
C57BL/6J m 0.0402 0.0   1   0.0 0.0 0.0402, 0.0402 -0.49
CAST/EiJ m 0.0313 0.0   1   0.0 0.0 0.0313, 0.0313 -0.54
DBA/2J m 0.149 0.0   1   0.0 0.0 0.149, 0.149 0.19
FVB/NJ m 0.114 0.0   1   0.0 0.0 0.114, 0.114 -0.03
NOD/ShiLtJ m 0.0219 0.0   1   0.0 0.0 0.0219, 0.0219 -0.6
NZW/LacJ m 0.0433 0.0   3 0.0 0.0 0.0433, 0.0433 -0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.108 0.0007 0.1096 0.1064
BALB/cByJ m 0.0615 0.0006 0.0628 0.0602
C3H/HeJ m 0.0815 0.0006 0.0828 0.0802
NZW/LacJ m 0.0433 0.0006 0.0446 0.042




  GWAS USING LINEAR MIXED MODELS