Project measure / variable:   Rusyn2   TCA_24_tce

ID, description, units MPD:36177   TCA_24_tce   trichloroacetic acid (serum TCA)   [nmol/mL]  24h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   13 strains     sex: m     age: 7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn2 - trichloroacetic acid (serum TCA) 24h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested13 strains
Mean of the strain means157   nmol/mL
Median of the strain means152   nmol/mL
SD of the strain means± 106
Coefficient of variation (CV)0.674
Min–max range of strain means17.1   –   413   nmol/mL
Mean sample size per strain2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 10 251367.1798 25136.718 16.5743 < 0.0001
Residuals 18 27298.9133 1516.6063


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 413.0 0.0   2   0.0 0.0 413.0, 413.0 2.41
A/J m 175.0 0.0   2   0.0 0.0 175.0, 175.0 0.17
B6C3F1/J m 212.0 18.7   3 10.8 0.0884 191.0, 227.0 0.52
BALB/cByJ m 152.0 0.0   3 0.0 0.0 152.0, 152.0 -0.05
BTBR T+ Itpr3tf/J m 136.0 93.6   2   66.2 0.689 69.6, 202.0 -0.2
C3H/HeJ m 168.0 34.6   3 20.0 0.206 148.0, 208.0 0.1
C57BL/6J m 74.2 0.0   1   0.0 0.0 74.2, 74.2 -0.78
CAST/EiJ m 17.1 0.0   1   0.0 0.0 17.1, 17.1 -1.32
DBA/2J m 208.0 32.5   2   23.0 0.156 185.0, 231.0 0.48
FVB/NJ m 81.5 26.4   3 15.3 0.324 56.3, 109.0 -0.71
KK/HlJ m 38.1 1.27   3 0.733 0.0334 36.6, 38.8 -1.12
NOD/ShiLtJ m 98.4 80.5   3 46.5 0.819 11.2, 170.0 -0.56
NZW/LacJ m 271.0 0.0   3 0.0 0.0 271.0, 271.0 1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 413.0 27.5373 470.8537 355.1463
A/J m 175.0 27.5373 232.8537 117.1463
B6C3F1/J m 212.0 22.4841 259.2374 164.7626
BALB/cByJ m 152.0 22.4841 199.2374 104.7626
BTBR T+ Itpr3tf/J m 135.8 27.5373 193.6537 77.9463
C3H/HeJ m 168.0 22.4841 215.2374 120.7626
DBA/2J m 208.0 27.5373 265.8537 150.1463
FVB/NJ m 81.4667 22.4841 128.704 34.2293
KK/HlJ m 38.0667 22.4841 85.304 0.0
NOD/ShiLtJ m 98.4 22.4841 145.6374 51.1626
NZW/LacJ m 271.0 22.4841 318.2374 223.7626




  GWAS USING LINEAR MIXED MODELS