Project measure / variable:   Rusyn2   AST_24_tce

ID, description, units MPD:36129   AST_24_tce   aspartate transaminase (serum AST), treated group   [IU/L]  24h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   15 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - aspartate transaminase (serum AST), treated group 24h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means165   IU/L
Median of the strain means144   IU/L
SD of the strain means± 82.2
Coefficient of variation (CV)0.497
Min–max range of strain means56.0   –   339   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 14 280878.8788 20062.7771 1.478 0.1816
Residuals 29 393650.6667 13574.1609


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 146.0 59.2   3 34.2 0.405 104.0, 214.0 -0.24
A/J m 122.0 7.07   2   5.0 0.058 117.0, 127.0 -0.53
AKR/J m 82.3 10.0   3 5.78 0.122 72.0, 92.0 -1.01
B6C3F1/J m 339.0 302.0   3 174.0 0.892 147.0, 687.0 2.11
BALB/cByJ m 251.0 13.6   3 7.84 0.0542 238.0, 265.0 1.04
BTBR T+ Itpr3tf/J m 56.0 14.7   3 8.5 0.263 43.0, 72.0 -1.33
C3H/HeJ m 261.0 282.0   3 163.0 1.08 80.0, 586.0 1.16
C57BL/6J m 111.0 12.5   3 7.22 0.113 102.0, 125.0 -0.66
DBA/2J m 110.0 13.3   3 7.67 0.121 102.0, 125.0 -0.67
FVB/NJ m 141.0 54.3   3 31.3 0.384 109.0, 204.0 -0.3
KK/HlJ m 114.0 42.3   3 24.4 0.372 69.0, 153.0 -0.63
MOLF/EiJ m 144.0 44.5   3 25.7 0.308 104.0, 192.0 -0.26
NOD/ShiLtJ m 159.0 30.7   3 17.8 0.194 138.0, 194.0 -0.08
NZW/LacJ m 150.0 38.0   3 21.9 0.253 125.0, 194.0 -0.19
PWD/PhJ m 295.0 111.0   3 64.2 0.377 212.0, 421.0 1.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 146.3333 67.266 283.9078 8.7588
A/J m 122.0 82.3837 290.4937 0.0
AKR/J m 82.3333 67.266 219.9078 0.0
B6C3F1/J m 338.6667 67.266 476.2412 201.0922
BALB/cByJ m 250.6667 67.266 388.2412 113.0922
BTBR T+ Itpr3tf/J m 56.0 67.266 193.5745 0.0
C3H/HeJ m 260.6667 67.266 398.2412 123.0922
C57BL/6J m 110.6667 67.266 248.2412 0.0
DBA/2J m 109.6667 67.266 247.2412 0.0
FVB/NJ m 141.3333 67.266 278.9078 3.7588
KK/HlJ m 113.6667 67.266 251.2412 0.0
MOLF/EiJ m 144.3333 67.266 281.9078 6.7588
NOD/ShiLtJ m 158.6667 67.266 296.2412 21.0922
NZW/LacJ m 150.3333 67.266 287.9078 12.7588
PWD/PhJ m 294.6667 67.266 432.2412 157.0922




  GWAS USING LINEAR MIXED MODELS