Project measure / variable:   Rusyn2   AST_8_tce

ID, description, units MPD:36128   AST_8_tce   aspartate transaminase (serum AST), treated group   [IU/L]  8h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   16 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - aspartate transaminase (serum AST), treated group 8h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested16 strains
Mean of the strain means171   IU/L
Median of the strain means140   IU/L
SD of the strain means± 88.0
Coefficient of variation (CV)0.514
Min–max range of strain means64.3   –   327   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 15 348456.6458 23230.4431 1.8206 0.076
Residuals 32 408309.3333 12759.6667


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 130.0 37.9   3 21.9 0.292 89.0, 164.0 -0.47
A/J m 153.0 54.3   3 31.3 0.355 110.0, 214.0 -0.21
AKR/J m 204.0 67.2   3 38.8 0.329 134.0, 268.0 0.37
B6C3F1/J m 88.3 50.5   3 29.2 0.572 52.0, 146.0 -0.94
BALB/cByJ m 254.0 199.0   3 115.0 0.786 74.0, 468.0 0.94
BTBR T+ Itpr3tf/J m 85.0 49.5   3 28.6 0.582 53.0, 142.0 -0.98
C3H/HeJ m 96.0 30.8   3 17.8 0.321 63.0, 124.0 -0.85
C57BL/6J m 107.0 35.0   3 20.2 0.327 82.0, 147.0 -0.73
DBA/2J m 118.0 23.6   3 13.6 0.2 92.0, 138.0 -0.6
FVB/NJ m 135.0 69.4   3 40.1 0.514 57.0, 190.0 -0.41
KK/HlJ m 64.3 25.1   3 14.5 0.391 46.0, 93.0 -1.21
MOLF/EiJ m 327.0 167.0   3 96.5 0.511 138.0, 455.0 1.77
NOD/ShiLtJ m 303.0 198.0   3 114.0 0.655 132.0, 520.0 1.5
NZW/LacJ m 145.0 3.79   3 2.19 0.0262 142.0, 149.0 -0.3
PWD/PhJ m 207.0 241.0   3 139.0 1.17 64.0, 485.0 0.41
WSB/EiJ m 323.0 131.0   3 75.4 0.404 200.0, 460.0 1.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 129.6667 65.2167 262.5088 0.0
A/J m 153.0 65.2167 285.8421 20.1579
AKR/J m 204.3333 65.2167 337.1755 71.4912
B6C3F1/J m 88.3333 65.2167 221.1755 0.0
BALB/cByJ m 253.6667 65.2167 386.5088 120.8245
BTBR T+ Itpr3tf/J m 85.0 65.2167 217.8421 0.0
C3H/HeJ m 96.0 65.2167 228.8421 0.0
C57BL/6J m 107.0 65.2167 239.8421 0.0
DBA/2J m 118.0 65.2167 250.8421 0.0
FVB/NJ m 135.0 65.2167 267.8421 2.1579
KK/HlJ m 64.3333 65.2167 197.1755 0.0
MOLF/EiJ m 327.0 65.2167 459.8421 194.1579
NOD/ShiLtJ m 302.6667 65.2167 435.5088 169.8245
NZW/LacJ m 144.6667 65.2167 277.5088 11.8245
PWD/PhJ m 206.6667 65.2167 339.5088 73.8245
WSB/EiJ m 323.0 65.2167 455.8421 190.1579




  GWAS USING LINEAR MIXED MODELS