Project measure / variable:   Rusyn2   AST_2_tce

ID, description, units MPD:36127   AST_2_tce   aspartate transaminase (serum AST), treated group   [IU/L]  2h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   15 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - aspartate transaminase (serum AST), treated group 2h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means169   IU/L
Median of the strain means177   IU/L
SD of the strain means± 54.8
Coefficient of variation (CV)0.325
Min–max range of strain means102   –   283   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 14 126694.3111 9049.5937 0.7802 0.6813
Residuals 30 347970.6667 11599.0222


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 117.0 52.7   3 30.4 0.451 70.0, 174.0 -0.94
A/J m 192.0 50.3   3 29.0 0.262 135.0, 231.0 0.43
AKR/J m 177.0 59.0   3 34.1 0.333 110.0, 220.0 0.15
B6C3F1/J m 115.0 27.8   3 16.1 0.242 85.0, 140.0 -0.98
BALB/cByJ m 112.0 57.6   3 33.2 0.515 48.0, 160.0 -1.03
BTBR T+ Itpr3tf/J m 102.0 15.7   3 9.07 0.154 91.0, 120.0 -1.21
C3H/HeJ m 203.0 36.6   3 21.1 0.18 168.0, 241.0 0.63
C57BL/6J m 206.0 100.0   3 57.8 0.487 134.0, 320.0 0.68
DBA/2J m 139.0 30.6   3 17.7 0.22 117.0, 174.0 -0.54
FVB/NJ m 134.0 20.3   3 11.7 0.152 120.0, 157.0 -0.63
KK/HlJ m 283.0 343.0   3 198.0 1.21 67.0, 679.0 2.09
MOLF/EiJ m 185.0 68.6   3 39.6 0.37 138.0, 264.0 0.3
NOD/ShiLtJ m 240.0 63.5   3 36.6 0.264 198.0, 313.0 1.3
NZW/LacJ m 111.0 16.2   3 9.33 0.145 94.0, 126.0 -1.05
PWD/PhJ m 212.0 146.0   3 84.5 0.689 105.0, 379.0 0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 117.0 62.1799 243.9883 0.0
A/J m 191.6667 62.1799 318.655 64.6784
AKR/J m 177.3333 62.1799 304.3216 50.345
B6C3F1/J m 115.0 62.1799 241.9883 0.0
BALB/cByJ m 111.6667 62.1799 238.655 0.0
BTBR T+ Itpr3tf/J m 102.0 62.1799 228.9883 0.0
C3H/HeJ m 203.3333 62.1799 330.3216 76.345
C57BL/6J m 205.6667 62.1799 332.655 78.6784
DBA/2J m 139.0 62.1799 265.9883 12.0117
FVB/NJ m 133.6667 62.1799 260.655 6.6784
KK/HlJ m 283.3333 62.1799 410.3216 156.345
MOLF/EiJ m 185.3333 62.1799 312.3216 58.345
NOD/ShiLtJ m 240.0 62.1799 366.9883 113.0117
NZW/LacJ m 111.3333 62.1799 238.3216 0.0
PWD/PhJ m 212.3333 62.1799 339.3216 85.345




  GWAS USING LINEAR MIXED MODELS