Project measure / variable:   Rusyn2   AST_2_ctrl

ID, description, units MPD:36122   AST_2_ctrl   aspartate transaminase (serum AST), control group   [IU/L]  2h after baseline  
trichloroethylene study
Data set, strains Rusyn2   inbred   15 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - aspartate transaminase (serum AST), control group 2h after baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means231   IU/L
Median of the strain means175   IU/L
SD of the strain means± 208
Coefficient of variation (CV)0.902
Min–max range of strain means79.7   –   909   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 14 1823863.2444 130275.946 1.4424 0.1942
Residuals 30 2709504.0 90316.8


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 79.7 11.6   3 6.69 0.145 72.0, 93.0 -0.73
A/J m 472.0 269.0   3 155.0 0.568 170.0, 683.0 1.16
AKR/J m 114.0 15.6   3 9.02 0.137 100.0, 131.0 -0.56
B6C3F1/J m 175.0 109.0   3 62.7 0.622 98.0, 299.0 -0.27
BALB/cByJ m 113.0 46.5   3 26.9 0.413 76.0, 165.0 -0.57
BTBR T+ Itpr3tf/J m 143.0 75.2   3 43.4 0.527 56.0, 190.0 -0.42
C3H/HeJ m 217.0 41.8   3 24.1 0.192 189.0, 265.0 -0.07
C57BL/6J m 209.0 6.81   3 3.93 0.0325 204.0, 217.0 -0.1
DBA/2J m 179.0 69.5   3 40.1 0.389 105.0, 243.0 -0.25
FVB/NJ m 169.0 62.4   3 36.0 0.369 131.0, 241.0 -0.3
KK/HlJ m 127.0 30.6   3 17.7 0.242 92.0, 150.0 -0.5
MOLF/EiJ m 231.0 138.0   3 80.0 0.6 108.0, 381.0 0.0
NOD/ShiLtJ m 909.0 1108.0   3 639.0 1.22 193.0, 2185.0 3.26
NZW/LacJ m 149.0 34.7   3 20.0 0.233 110.0, 177.0 -0.39
PWD/PhJ m 175.0 64.6   3 37.3 0.37 126.0, 248.0 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 79.6667 173.5097 434.0207 0.0
A/J m 472.3333 173.5097 826.6873 117.9793
AKR/J m 114.3333 173.5097 468.6873 0.0
B6C3F1/J m 174.6667 173.5097 529.0207 0.0
BALB/cByJ m 112.6667 173.5097 467.0207 0.0
BTBR T+ Itpr3tf/J m 142.6667 173.5097 497.0207 0.0
C3H/HeJ m 217.0 173.5097 571.354 0.0
C57BL/6J m 209.3333 173.5097 563.6873 0.0
DBA/2J m 178.6667 173.5097 533.0207 0.0
FVB/NJ m 169.0 173.5097 523.354 0.0
KK/HlJ m 126.6667 173.5097 481.0207 0.0
MOLF/EiJ m 231.0 173.5097 585.354 0.0
NOD/ShiLtJ m 909.3333 173.5097 1263.6873 554.9793
NZW/LacJ m 148.6667 173.5097 503.0207 0.0
PWD/PhJ m 174.6667 173.5097 529.0207 0.0




  GWAS USING LINEAR MIXED MODELS