Project measure / variable:   Rusyn2   ALT_24_ctrl

ID, description, units MPD:36114   ALT_24_ctrl   alanine transaminase (serum ALT), control group   [IU/L]  24h after baseline  
trichloroethylene study
Data set, strains Rusyn2   inbred   16 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - alanine transaminase (serum ALT), control group 24h after baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested16 strains
Mean of the strain means51.2   IU/L
Median of the strain means38.0   IU/L
SD of the strain means± 35.7
Coefficient of variation (CV)0.696
Min–max range of strain means15.2   –   137   IU/L
Mean sample size per strain2.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 15 53707.1047 3580.4736 2.1018 0.0407
Residuals 30 51106.3033 1703.5434


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 21.2 2.71   3 1.56 0.127 18.2, 23.4 -0.84
A/J m 137.0 108.0   3 62.4 0.787 37.2, 252.0 2.41
AKR/J m 15.2 5.64   3 3.25 0.37 8.9, 19.7 -1.01
B6C3F1/J m 85.1 77.0   3 44.4 0.904 40.2, 174.0 0.95
BALB/cByJ m 58.4 61.7   2   43.6 1.06 14.7, 102.0 0.2
BTBR T+ Itpr3tf/J m 21.8 3.88   3 2.24 0.178 18.2, 25.9 -0.83
C3H/HeJ m 67.1 38.1   3 22.0 0.568 42.7, 111.0 0.44
C57BL/6J m 31.0 3.62   3 2.09 0.117 27.0, 34.1 -0.57
CAST/EiJ m 32.4 7.83   3 4.52 0.242 25.5, 40.9 -0.53
DBA/2J m 29.2 19.8   3 11.4 0.678 9.1, 48.7 -0.62
FVB/NJ m 25.2 9.35   3 5.4 0.37 19.2, 36.0 -0.73
KK/HlJ m 49.7 17.4   3 10.1 0.35 30.1, 63.4 -0.04
MOLF/EiJ m 74.1 53.2   3 30.7 0.718 15.8, 120.0 0.64
NOD/ShiLtJ m 111.0 29.6   2   21.0 0.267 90.1, 132.0 1.68
NZW/LacJ m 17.9 3.22   3 1.86 0.18 15.1, 21.4 -0.94
PWD/PhJ m 43.5 19.8   3 11.4 0.454 26.6, 65.2 -0.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 21.2333 23.8296 69.8998 0.0
A/J m 137.4 23.8296 186.0664 88.7336
AKR/J m 15.2333 23.8296 63.8998 0.0
B6C3F1/J m 85.1333 23.8296 133.7998 36.4669
BALB/cByJ m 58.35 29.1851 117.954 0.0
BTBR T+ Itpr3tf/J m 21.7667 23.8296 70.4331 0.0
C3H/HeJ m 67.0667 23.8296 115.7331 18.4002
C57BL/6J m 30.9667 23.8296 79.6331 0.0
CAST/EiJ m 32.3667 23.8296 81.0331 0.0
DBA/2J m 29.2333 23.8296 77.8998 0.0
FVB/NJ m 25.2333 23.8296 73.8998 0.0
KK/HlJ m 49.7 23.8296 98.3664 1.0336
MOLF/EiJ m 74.1 23.8296 122.7664 25.4336
NOD/ShiLtJ m 111.05 29.1851 170.654 51.446
NZW/LacJ m 17.8667 23.8296 66.5331 0.0
PWD/PhJ m 43.4667 23.8296 92.1331 0.0




  GWAS USING LINEAR MIXED MODELS