Project measure / variable:   Rusyn2   ALT_2_ctrl

ID, description, units MPD:36112   ALT_2_ctrl   alanine transaminase (serum ALT), control group   [IU/L]  2h after baseline  
trichloroethylene study
Data set, strains Rusyn2   inbred   16 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - alanine transaminase (serum ALT), control group 2h after baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested16 strains
Mean of the strain means62.1   IU/L
Median of the strain means52.9   IU/L
SD of the strain means± 31.2
Coefficient of variation (CV)0.502
Min–max range of strain means30.4   –   134   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 15 42670.8607 2844.724 1.5359 0.1523
Residuals 31 57415.3517 1852.1081


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 30.4 8.92   3 5.15 0.294 20.2, 36.9 -1.02
A/J m 125.0 69.1   3 39.9 0.551 63.4, 200.0 2.02
AKR/J m 38.8 16.7   3 9.64 0.43 27.5, 58.0 -0.75
B6C3F1/J m 77.4 90.6   3 52.3 1.17 22.2, 182.0 0.49
BALB/cByJ m 43.0 8.74   3 5.05 0.203 33.8, 51.2 -0.61
BTBR T+ Itpr3tf/J m 41.5 6.4   3 3.69 0.154 36.0, 48.5 -0.66
C3H/HeJ m 45.9 7.48   3 4.32 0.163 40.3, 54.4 -0.52
C57BL/6J m 52.1 10.0   3 5.79 0.192 40.9, 60.2 -0.32
CAST/EiJ m 54.6 28.5   3 16.5 0.522 37.1, 87.5 -0.24
DBA/2J m 43.9 24.1   3 13.9 0.549 28.2, 71.7 -0.58
FVB/NJ m 59.3 21.6   3 12.5 0.364 36.6, 79.6 -0.09
KK/HlJ m 62.2 32.1   3 18.6 0.517 37.7, 98.6 0.0
MOLF/EiJ m 134.0 102.0   3 59.1 0.762 35.7, 240.0 2.31
NOD/ShiLtJ m 97.8 27.2   2   19.2 0.279 78.5, 117.0 1.14
NZW/LacJ m 53.6 35.9   3 20.7 0.669 28.3, 94.7 -0.27
PWD/PhJ m 34.5 7.6   3 4.39 0.221 26.4, 41.5 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 30.3667 24.8469 81.0423 0.0
A/J m 125.4667 24.8469 176.1423 74.791
AKR/J m 38.8333 24.8469 89.509 0.0
B6C3F1/J m 77.4333 24.8469 128.109 26.7577
BALB/cByJ m 43.0 24.8469 93.6756 0.0
BTBR T+ Itpr3tf/J m 41.4667 24.8469 92.1423 0.0
C3H/HeJ m 45.9 24.8469 96.5756 0.0
C57BL/6J m 52.1333 24.8469 102.809 1.4577
CAST/EiJ m 54.6 24.8469 105.2756 3.9244
DBA/2J m 43.9333 24.8469 94.609 0.0
FVB/NJ m 59.3 24.8469 109.9756 8.6244
KK/HlJ m 62.2 24.8469 112.8756 11.5244
MOLF/EiJ m 134.2333 24.8469 184.909 83.5577
NOD/ShiLtJ m 97.75 30.4311 159.8147 35.6853
NZW/LacJ m 53.6333 24.8469 104.309 2.9577
PWD/PhJ m 34.4667 24.8469 85.1423 0.0




  GWAS USING LINEAR MIXED MODELS