Project measure / variable:   Berndt2   exp_flow_mch5

ID, description, units MPD:35149   exp_flow_mch5   expiratory flow rate   [mL/kg/s]  5 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - expiratory flow rate 5 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means1.20   mL/kg/s 1.35   mL/kg/s
Median of the strain means1.12   mL/kg/s 1.24   mL/kg/s
SD of the strain means± 0.343 ± 0.510
Coefficient of variation (CV)0.286 0.377
Min–max range of strain means0.723   –   2.05   mL/kg/s 0.847   –   3.52   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.5799 2.5799 14.2322 0.0002
strain 28 74.2828 2.653 14.6354 < 0.0001
sex:strain 28 11.8636 0.4237 2.3374 0.0002
Residuals 412 74.6831 0.1813


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.792 0.279   8 0.0985 0.352 0.499, 1.23 -1.19
129S1/SvImJ m 0.948 0.472   8 0.167 0.498 0.495, 1.69 -0.79
A/J f 1.41 0.275   8 0.0971 0.196 1.04, 1.78 0.61
A/J m 1.37 0.276   8 0.0977 0.202 1.01, 1.87 0.04
AKR/J f 1.51 0.695   8 0.246 0.462 0.904, 3.12 0.9
AKR/J m 1.14 0.284   8 0.1 0.25 0.78, 1.72 -0.41
BALB/cByJ f 1.49 0.302   8 0.107 0.203 1.01, 1.91 0.84
BALB/cByJ m 1.7 0.389   8 0.138 0.229 1.11, 2.25 0.68
BALB/cJ f 1.98 0.441   10 0.139 0.223 1.25, 2.66 2.27
BALB/cJ m 2.16 0.499   10 0.158 0.231 1.67, 3.31 1.59
BTBR T+ Itpr3tf/J f 2.05 0.868   8 0.307 0.423 1.03, 3.82 2.47
BTBR T+ Itpr3tf/J m 3.52 0.634   8 0.224 0.18 2.72, 4.61 4.26
BUB/BnJ f 1.34 0.389   7 0.147 0.29 0.782, 1.94 0.4
BUB/BnJ m 1.08 0.437   8 0.155 0.405 0.642, 1.95 -0.53
C3H/HeJ f 0.935 0.266   8 0.0939 0.284 0.464, 1.33 -0.78
C3H/HeJ m 1.08 0.422   8 0.149 0.39 0.593, 1.95 -0.53
C57BL/10J f 1.4 0.293   8 0.104 0.21 0.916, 1.9 0.58
C57BL/10J m 1.56 0.413   7 0.156 0.264 1.04, 2.29 0.41
C57BL/6J f 1.06 0.165   7 0.0625 0.156 0.828, 1.29 -0.41
C57BL/6J m 1.16 0.381   13 0.106 0.329 0.575, 2.02 -0.37
C57BLKS/J f 1.15 0.305   11 0.0921 0.265 0.571, 1.51 -0.15
C57BLKS/J m 1.21 0.351   8 0.124 0.29 0.708, 1.65 -0.28
C57BR/cdJ f 1.86 1.31   6 0.536 0.707 0.939, 4.48 1.92
C57BR/cdJ m 1.47 0.604   8 0.213 0.411 0.809, 2.48 0.23
C57L/J f 1.21 0.212   8 0.075 0.176 0.877, 1.4 0.02
C57L/J m 1.38 0.28   8 0.0991 0.203 1.01, 1.94 0.06
CBA/J f 1.12 0.0853   8 0.0301 0.0759 0.979, 1.25 -0.24
CBA/J m 1.24 0.202   8 0.0714 0.163 0.896, 1.52 -0.22
CE/J f 1.07 0.312   8 0.11 0.292 0.502, 1.62 -0.39
CE/J m 1.26 0.395   9 0.132 0.314 0.532, 1.94 -0.18
DBA/1J f 1.12 0.358   10 0.113 0.32 0.484, 1.66 -0.24
DBA/1J m 1.37 0.297   8 0.105 0.217 0.947, 1.81 0.04
DBA/2J f 1.2 0.229   8 0.0808 0.19 0.816, 1.48 -0.01
DBA/2J m 1.24 0.234   10 0.074 0.189 0.836, 1.53 -0.22
FVB/NJ f 1.11 0.449   8 0.159 0.406 0.71, 1.89 -0.27
FVB/NJ m 1.79 0.877   7 0.332 0.491 1.0, 3.39 0.86
I/LnJ f 1.07 0.341   7 0.129 0.319 0.572, 1.6 -0.39
I/LnJ m 1.29 0.206   5 0.0922 0.16 0.986, 1.52 -0.12
KK/HlJ f 1.14 0.161   8 0.057 0.141 0.86, 1.33 -0.18
KK/HlJ m 1.05 0.312   6 0.127 0.296 0.666, 1.47 -0.59
LP/J f 0.723 0.351   8 0.124 0.485 0.288, 1.29 -1.4
LP/J m 0.927 0.405   8 0.143 0.437 0.353, 1.62 -0.83
NOD/ShiLtJ f 0.863 0.389   8 0.138 0.451 0.591, 1.8 -0.99
NOD/ShiLtJ m 1.29 0.866   8 0.306 0.674 0.712, 3.18 -0.12
NON/ShiLtJ f 0.94 0.325   8 0.115 0.346 0.54, 1.62 -0.76
NON/ShiLtJ m 1.16 0.364   8 0.129 0.315 0.797, 1.63 -0.37
NZW/LacJ f 1.27 0.23   8 0.0814 0.181 0.909, 1.49 0.2
NZW/LacJ m 1.22 0.211   8 0.0745 0.173 0.908, 1.54 -0.26
PL/J f 0.82 0.184   8 0.0651 0.224 0.627, 1.17 -1.11
PL/J m 0.847 0.267   8 0.0945 0.316 0.571, 1.22 -0.99
RIIIS/J f 1.06 0.154   8 0.0546 0.145 0.882, 1.26 -0.41
RIIIS/J m 1.23 0.173   8 0.0613 0.141 0.947, 1.44 -0.24
SJL/J f 0.844 0.33   8 0.117 0.391 0.444, 1.36 -1.04
SJL/J m 0.875 0.327   8 0.115 0.373 0.588, 1.43 -0.93
SM/J f 1.5 0.455   8 0.161 0.303 0.89, 2.21 0.87
SM/J m 1.67 0.815   8 0.288 0.487 0.924, 3.42 0.63
SWR/J f 0.827 0.208   8 0.0735 0.251 0.54, 1.09 -1.09
SWR/J m 0.938 0.189   9 0.0629 0.201 0.667, 1.32 -0.81


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.792 0.1505 1.0879 0.4961
129S1/SvImJ m 0.948 0.1505 1.2439 0.6521
A/J f 1.405 0.1505 1.7009 1.1091
A/J m 1.3675 0.1505 1.6634 1.0716
AKR/J f 1.5055 0.1505 1.8014 1.2096
AKR/J m 1.1369 0.1505 1.4328 0.841
BALB/cByJ f 1.4925 0.1505 1.7884 1.1966
BALB/cByJ m 1.7038 0.1505 1.9996 1.4079
BALB/cJ f 1.979 0.1346 2.2437 1.7143
BALB/cJ m 2.157 0.1346 2.4217 1.8923
BTBR T+ Itpr3tf/J f 2.0525 0.1505 2.3484 1.7566
BTBR T+ Itpr3tf/J m 3.52 0.1505 3.8159 3.2241
BUB/BnJ f 1.3417 0.1609 1.658 1.0254
BUB/BnJ m 1.0809 0.1505 1.3768 0.785
C3H/HeJ f 0.9346 0.1505 1.2305 0.6387
C3H/HeJ m 1.083 0.1505 1.3789 0.7871
C57BL/10J f 1.3957 0.1505 1.6916 1.0999
C57BL/10J m 1.56 0.1609 1.8763 1.2437
C57BL/6J f 1.0626 0.1609 1.3789 0.7462
C57BL/6J m 1.1592 0.1181 1.3913 0.927
C57BLKS/J f 1.1535 0.1284 1.4059 0.9012
C57BLKS/J m 1.2119 0.1505 1.5078 0.916
C57BR/cdJ f 1.8582 0.1738 2.1998 1.5165
C57BR/cdJ m 1.468 0.1505 1.7639 1.1721
C57L/J f 1.2079 0.1505 1.5038 0.912
C57L/J m 1.38 0.1505 1.6759 1.0841
CBA/J f 1.1236 0.1505 1.4195 0.8277
CBA/J m 1.237 0.1505 1.5329 0.9411
CE/J f 1.0677 0.1505 1.3636 0.7719
CE/J m 1.2591 0.1419 1.5381 0.9801
DBA/1J f 1.1179 0.1346 1.3826 0.8532
DBA/1J m 1.3709 0.1505 1.6668 1.075
DBA/2J f 1.2007 0.1505 1.4966 0.9049
DBA/2J m 1.2366 0.1346 1.5013 0.9719
FVB/NJ f 1.106 0.1505 1.4019 0.8101
FVB/NJ m 1.7871 0.1609 2.1035 1.4708
I/LnJ f 1.069 0.1609 1.3853 0.7527
I/LnJ m 1.2872 0.1904 1.6615 0.9129
KK/HlJ f 1.144 0.1505 1.4399 0.8481
KK/HlJ m 1.0542 0.1738 1.3958 0.7125
LP/J f 0.7232 0.1505 1.0191 0.4274
LP/J m 0.9265 0.1505 1.2224 0.6306
NOD/ShiLtJ f 0.8632 0.1505 1.1591 0.5674
NOD/ShiLtJ m 1.2853 0.1505 1.5811 0.9894
NON/ShiLtJ f 0.94 0.1505 1.2359 0.6441
NON/ShiLtJ m 1.1576 0.1505 1.4535 0.8617
NZW/LacJ f 1.2721 0.1505 1.568 0.9762
NZW/LacJ m 1.2191 0.1505 1.515 0.9232
PL/J f 0.8204 0.1505 1.1163 0.5245
PL/J m 0.8468 0.1505 1.1426 0.5509
RIIIS/J f 1.0619 0.1505 1.3578 0.766
RIIIS/J m 1.2321 0.1505 1.528 0.9362
SJL/J f 0.8436 0.1505 1.1395 0.5477
SJL/J m 0.8746 0.1505 1.1705 0.5787
SM/J f 1.5037 0.1505 1.7996 1.2079
SM/J m 1.6743 0.1505 1.9701 1.3784
SWR/J f 0.8274 0.1505 1.1233 0.5315
SWR/J m 0.9381 0.1419 1.2171 0.6591


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.87 0.1064 1.0792 0.6608
A/J both 1.3862 0.1064 1.5955 1.177
AKR/J both 1.3212 0.1064 1.5304 1.112
BALB/cByJ both 1.5981 0.1064 1.8074 1.3889
BALB/cJ both 2.068 0.0952 2.2551 1.8809
BTBR T+ Itpr3tf/J both 2.7862 0.1064 2.9955 2.577
BUB/BnJ both 1.2113 0.1102 1.4279 0.9947
C3H/HeJ both 1.0088 0.1064 1.218 0.7996
C57BL/10J both 1.4779 0.1102 1.6945 1.2613
C57BL/6J both 1.1109 0.0998 1.307 0.9147
C57BLKS/J both 1.1827 0.0989 1.3772 0.9883
C57BR/cdJ both 1.6631 0.115 1.8891 1.4371
C57L/J both 1.2939 0.1064 1.5032 1.0847
CBA/J both 1.1803 0.1064 1.3895 0.9711
CE/J both 1.1634 0.1034 1.3668 0.9601
DBA/1J both 1.2444 0.101 1.4429 1.0459
DBA/2J both 1.2187 0.101 1.4172 1.0202
FVB/NJ both 1.4466 0.1102 1.6631 1.23
I/LnJ both 1.1781 0.1246 1.4231 0.9331
KK/HlJ both 1.0991 0.115 1.3251 0.8731
LP/J both 0.8249 0.1064 1.0341 0.6156
NOD/ShiLtJ both 1.0742 0.1064 1.2835 0.865
NON/ShiLtJ both 1.0488 0.1064 1.258 0.8396
NZW/LacJ both 1.2456 0.1064 1.4549 1.0364
PL/J both 0.8336 0.1064 1.0428 0.6243
RIIIS/J both 1.147 0.1064 1.3562 0.9378
SJL/J both 0.8591 0.1064 1.0684 0.6499
SM/J both 1.589 0.1064 1.7982 1.3798
SWR/J both 0.8827 0.1034 1.0861 0.6794




  GWAS USING LINEAR MIXED MODELS