Phenotype measure:   Berndt2   exp_flow_saline


  STRAIN COMPARISON PLOT
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Berndt2 - expiratory flow rate saline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means1.32   mL/kg/s 1.43   mL/kg/s
Median of the strain means1.36   mL/kg/s 1.35   mL/kg/s
SD of the strain means± 0.358 ± 0.389
Coefficient of variation (CV)0.270 0.271
Min–max range of strain means0.749   –   2.27   mL/kg/s 0.899   –   2.58   mL/kg/s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.6184 1.6184 5.9218 0.0154
strain 28 57.7964 2.0642 7.553 < 0.0001
sex:strain 28 7.5131 0.2683 0.9818 0.4942
Residuals 412 112.5948 0.2733


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.995 0.3   8 0.106 0.302 0.492, 1.42 -0.92
129S1/SvImJ m 1.1 0.313   8 0.11 0.285 0.661, 1.58 -0.85
A/J f 1.37 0.263   8 0.0928 0.192 0.985, 1.73 0.13
A/J m 1.49 0.371   8 0.131 0.249 1.07, 2.07 0.15
AKR/J f 1.36 0.569   8 0.201 0.419 0.766, 2.63 0.1
AKR/J m 1.15 0.315   8 0.111 0.275 0.78, 1.71 -0.72
BALB/cByJ f 1.64 0.376   8 0.133 0.229 0.899, 2.09 0.88
BALB/cByJ m 1.97 0.596   8 0.211 0.302 1.38, 3.21 1.39
BALB/cJ f 2.27 1.38   10 0.437 0.609 0.847, 5.82 2.64
BALB/cJ m 2.15 0.696   10 0.22 0.324 0.996, 3.32 1.85
BTBR T+ Itpr3tf/J f 1.93 0.607   8 0.215 0.315 1.06, 2.99 1.69
BTBR T+ Itpr3tf/J m 2.58 0.747   8 0.264 0.289 1.67, 3.67 2.96
BUB/BnJ f 1.55 0.779   7 0.294 0.501 0.815, 2.81 0.63
BUB/BnJ m 1.46 0.412   8 0.146 0.283 1.05, 2.23 0.07
C3H/HeJ f 1.17 0.379   8 0.134 0.325 0.733, 2.01 -0.43
C3H/HeJ m 1.04 0.242   8 0.0855 0.233 0.771, 1.4 -1.01
C57BL/10J f 1.61 0.704   8 0.249 0.438 1.21, 3.29 0.8
C57BL/10J m 1.77 0.396   7 0.15 0.224 1.27, 2.3 0.87
C57BL/6J f 1.43 0.593   7 0.224 0.413 0.938, 2.49 0.3
C57BL/6J m 1.72 0.878   13 0.244 0.509 0.885, 3.72 0.74
C57BLKS/J f 1.39 0.479   11 0.144 0.346 0.769, 2.32 0.18
C57BLKS/J m 1.26 0.231   8 0.0815 0.183 0.908, 1.58 -0.44
C57BR/cdJ f 1.73 1.11   6 0.453 0.641 0.763, 3.83 1.13
C57BR/cdJ m 1.63 0.409   8 0.145 0.251 1.19, 2.36 0.51
C57L/J f 1.4 0.297   8 0.105 0.212 1.01, 1.91 0.21
C57L/J m 1.28 0.369   8 0.13 0.288 0.871, 1.86 -0.39
CBA/J f 1.04 0.189   8 0.0668 0.182 0.768, 1.27 -0.8
CBA/J m 1.35 0.427   8 0.151 0.317 0.961, 2.16 -0.21
CE/J f 1.87 0.893   8 0.316 0.479 0.693, 3.75 1.53
CE/J m 1.64 0.312   9 0.104 0.191 1.13, 2.11 0.54
DBA/1J f 1.1 0.365   10 0.115 0.331 0.404, 1.63 -0.63
DBA/1J m 1.09 0.303   8 0.107 0.279 0.695, 1.49 -0.88
DBA/2J f 1.25 0.307   8 0.109 0.246 0.858, 1.8 -0.21
DBA/2J m 1.53 0.326   10 0.103 0.213 1.15, 2.1 0.25
FVB/NJ f 1.11 0.466   8 0.165 0.421 0.709, 1.97 -0.6
FVB/NJ m 1.68 0.73   7 0.276 0.434 0.783, 2.97 0.64
I/LnJ f 0.997 0.217   7 0.0821 0.218 0.741, 1.34 -0.92
I/LnJ m 1.26 0.2   5 0.0896 0.159 1.02, 1.49 -0.44
KK/HlJ f 1.47 0.686   8 0.243 0.467 0.84, 2.54 0.41
KK/HlJ m 1.25 0.368   6 0.15 0.294 1.05, 1.99 -0.47
LP/J f 0.749 0.231   8 0.0818 0.309 0.431, 1.17 -1.61
LP/J m 1.21 0.471   8 0.167 0.39 0.753, 2.0 -0.57
NOD/ShiLtJ f 0.88 0.282   8 0.0995 0.32 0.578, 1.45 -1.24
NOD/ShiLtJ m 0.899 0.26   8 0.092 0.29 0.629, 1.4 -1.37
NON/ShiLtJ f 1.09 0.396   8 0.14 0.363 0.593, 1.66 -0.66
NON/ShiLtJ m 1.75 0.599   8 0.212 0.341 1.28, 3.14 0.82
NZW/LacJ f 1.04 0.202   8 0.0713 0.194 0.794, 1.36 -0.8
NZW/LacJ m 1.07 0.212   8 0.075 0.199 0.671, 1.32 -0.93
PL/J f 1.02 0.443   8 0.156 0.432 0.551, 1.99 -0.85
PL/J m 1.13 0.638   8 0.226 0.563 0.758, 2.67 -0.78
RIIIS/J f 1.55 0.728   8 0.258 0.469 0.914, 3.0 0.63
RIIIS/J m 1.39 0.198   8 0.07 0.143 1.03, 1.71 -0.11
SJL/J f 1.01 0.139   8 0.0493 0.138 0.764, 1.22 -0.88
SJL/J m 0.962 0.269   8 0.095 0.279 0.644, 1.3 -1.21
SM/J f 1.52 0.254   8 0.0898 0.167 1.13, 1.94 0.55
SM/J m 1.72 0.762   8 0.27 0.444 0.924, 3.16 0.74
SWR/J f 0.864 0.236   8 0.0835 0.274 0.639, 1.26 -1.29
SWR/J m 0.979 0.216   9 0.0721 0.221 0.622, 1.26 -1.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.9947 0.1848 1.3581 0.6314
129S1/SvImJ m 1.0963 0.1848 1.4596 0.7329
A/J f 1.3694 0.1848 1.7327 1.0061
A/J m 1.49 0.1848 1.8533 1.1267
AKR/J f 1.3601 0.1848 1.7234 0.9968
AKR/J m 1.147 0.1848 1.5103 0.7837
BALB/cByJ f 1.6424 0.1848 2.0057 1.2791
BALB/cByJ m 1.9713 0.1848 2.3346 1.6079
BALB/cJ f 2.2687 0.1653 2.5937 1.9437
BALB/cJ m 2.1526 0.1653 2.4776 1.8276
BTBR T+ Itpr3tf/J f 1.9262 0.1848 2.2896 1.5629
BTBR T+ Itpr3tf/J m 2.5838 0.1848 2.9471 2.2204
BUB/BnJ f 1.5537 0.1976 1.9421 1.1653
BUB/BnJ m 1.4575 0.1848 1.8208 1.0942
C3H/HeJ f 1.1654 0.1848 1.5287 0.8021
C3H/HeJ m 1.0396 0.1848 1.4029 0.6763
C57BL/10J f 1.6075 0.1848 1.9708 1.2442
C57BL/10J m 1.7686 0.1976 2.157 1.3802
C57BL/6J f 1.4349 0.1976 1.8233 1.0464
C57BL/6J m 1.7244 0.145 2.0094 1.4394
C57BLKS/J f 1.3859 0.1576 1.6958 1.0761
C57BLKS/J m 1.2635 0.1848 1.6268 0.9002
C57BR/cdJ f 1.7288 0.2134 2.1484 1.3093
C57BR/cdJ m 1.6313 0.1848 1.9946 1.2679
C57L/J f 1.4 0.1848 1.7633 1.0367
C57L/J m 1.2825 0.1848 1.6458 0.9192
CBA/J f 1.0356 0.1848 1.3989 0.6723
CBA/J m 1.3504 0.1848 1.7137 0.9871
CE/J f 1.8654 0.1848 2.2287 1.5021
CE/J m 1.6356 0.1743 1.9781 1.293
DBA/1J f 1.1031 0.1653 1.4281 0.7781
DBA/1J m 1.0863 0.1848 1.4496 0.7229
DBA/2J f 1.2485 0.1848 1.6118 0.8852
DBA/2J m 1.531 0.1653 1.856 1.206
FVB/NJ f 1.107 0.1848 1.4703 0.7437
FVB/NJ m 1.6847 0.1976 2.0731 1.2963
I/LnJ f 0.9969 0.1976 1.3853 0.6084
I/LnJ m 1.256 0.2338 1.7156 0.7964
KK/HlJ f 1.4681 0.1848 1.8314 1.1048
KK/HlJ m 1.25 0.2134 1.6695 0.8305
LP/J f 0.749 0.1848 1.1123 0.3857
LP/J m 1.2075 0.1848 1.5708 0.8442
NOD/ShiLtJ f 0.8796 0.1848 1.2429 0.5163
NOD/ShiLtJ m 0.8986 0.1848 1.2619 0.5353
NON/ShiLtJ f 1.0932 0.1848 1.4566 0.7299
NON/ShiLtJ m 1.7538 0.1848 2.1171 1.3904
NZW/LacJ f 1.0401 0.1848 1.4034 0.6768
NZW/LacJ m 1.0657 0.1848 1.4291 0.7024
PL/J f 1.0245 0.1848 1.3878 0.6612
PL/J m 1.1349 0.1848 1.4982 0.7716
RIIIS/J f 1.5526 0.1848 1.9159 1.1893
RIIIS/J m 1.3888 0.1848 1.7521 1.0254
SJL/J f 1.0137 0.1848 1.3771 0.6504
SJL/J m 0.9624 0.1848 1.3257 0.5991
SM/J f 1.5162 0.1848 1.8796 1.1529
SM/J m 1.718 0.1848 2.0813 1.3547
SWR/J f 0.8636 0.1848 1.2269 0.5003
SWR/J m 0.9793 0.1743 1.3219 0.6368


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.0455 0.1307 1.3024 0.7886
A/J both 1.4297 0.1307 1.6866 1.1728
AKR/J both 1.2536 0.1307 1.5105 0.9967
BALB/cByJ both 1.8068 0.1307 2.0637 1.5499
BALB/cJ both 2.2106 0.1169 2.4404 1.9809
BTBR T+ Itpr3tf/J both 2.255 0.1307 2.5119 1.9981
BUB/BnJ both 1.5056 0.1353 1.7715 1.2397
C3H/HeJ both 1.1025 0.1307 1.3594 0.8456
C57BL/10J both 1.688 0.1353 1.954 1.4221
C57BL/6J both 1.5796 0.1225 1.8205 1.3387
C57BLKS/J both 1.3247 0.1215 1.5635 1.086
C57BR/cdJ both 1.68 0.1412 1.9575 1.4026
C57L/J both 1.3412 0.1307 1.5982 1.0843
CBA/J both 1.193 0.1307 1.4499 0.9361
CE/J both 1.7505 0.127 2.0001 1.5008
DBA/1J both 1.0947 0.124 1.3384 0.851
DBA/2J both 1.3897 0.124 1.6335 1.146
FVB/NJ both 1.3959 0.1353 1.6618 1.1299
I/LnJ both 1.1264 0.1531 1.4273 0.8256
KK/HlJ both 1.3591 0.1412 1.6366 1.0816
LP/J both 0.9782 0.1307 1.2352 0.7213
NOD/ShiLtJ both 0.8891 0.1307 1.146 0.6322
NON/ShiLtJ both 1.4235 0.1307 1.6804 1.1666
NZW/LacJ both 1.0529 0.1307 1.3098 0.796
PL/J both 1.0797 0.1307 1.3366 0.8228
RIIIS/J both 1.4707 0.1307 1.7276 1.2138
SJL/J both 0.9881 0.1307 1.245 0.7312
SM/J both 1.6171 0.1307 1.874 1.3602
SWR/J both 0.9215 0.127 1.1711 0.6718




  GWAS USING LINEAR MIXED MODELS