Project measure / variable:   Berndt2   expiratory_slope

ID, description, units MPD:35125   expiratory_slope   expiratory phase   [s]  response index  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - expiratory phase response index



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means-0.0450   s -0.0492   s
Median of the strain means-0.0609   s -0.0206   s
SD of the strain means± 0.174 ± 0.192
Coefficient of variation (CV)-3.86 -3.89
Min–max range of strain means-0.405   –   0.386   s -0.290   –   0.429   s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0051 0.0051 0.1042 0.747
strain 28 13.4101 0.4789 9.7679 < 0.0001
sex:strain 28 1.7858 0.0638 1.3008 0.1429
Residuals 412 20.2008 0.049


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f -0.25 0.296   8 0.105 -1.19 -0.563, 0.212 -1.18
129S1/SvImJ m -0.223 0.294   8 0.104 -1.32 -0.585, 0.203 -0.91
A/J f 0.336 0.244   8 0.0862 0.725 0.034, 0.579 2.2
A/J m 0.429 0.161   8 0.0568 0.375 0.268, 0.734 2.5
AKR/J f -0.0214 0.11   8 0.0389 -5.15 -0.189, 0.134 0.14
AKR/J m -0.273 0.181   8 0.064 -0.663 -0.563, -0.019 -1.17
BALB/cByJ f -0.118 0.199   8 0.0702 -1.69 -0.431, 0.238 -0.42
BALB/cByJ m -0.201 0.105   8 0.037 -0.521 -0.35, -0.075 -0.79
BALB/cJ f -0.162 0.133   10 0.0421 -0.821 -0.329, 0.014 -0.67
BALB/cJ m -0.135 0.111   10 0.0352 -0.824 -0.302, 0.088 -0.45
BTBR T+ Itpr3tf/J f 0.386 0.359   8 0.127 0.931 -0.474, 0.611 2.48
BTBR T+ Itpr3tf/J m 0.415 0.193   8 0.0681 0.464 0.143, 0.775 2.42
BUB/BnJ f -0.00386 0.307   7 0.116 -79.6 -0.524, 0.422 0.24
BUB/BnJ m 0.00975 0.298   8 0.105 30.5 -0.358, 0.436 0.31
C3H/HeJ f -0.1 0.306   8 0.108 -3.06 -0.467, 0.319 -0.32
C3H/HeJ m -0.00287 0.231   8 0.0818 -80.4 -0.355, 0.264 0.24
C57BL/10J f -0.125 0.136   8 0.0481 -1.09 -0.346, 0.117 -0.46
C57BL/10J m 0.0139 0.116   7 0.0438 8.37 -0.148, 0.195 0.33
C57BL/6J f -0.269 0.189   7 0.0716 -0.703 -0.548, -0.01 -1.29
C57BL/6J m -0.28 0.143   13 0.0398 -0.511 -0.54, -0.118 -1.2
C57BLKS/J f -0.235 0.179   11 0.0539 -0.761 -0.506, 0.086 -1.1
C57BLKS/J m -0.18 0.257   8 0.0909 -1.43 -0.53, 0.236 -0.68
C57BR/cdJ f -0.15 0.209   6 0.0852 -1.39 -0.382, 0.15 -0.61
C57BR/cdJ m -0.102 0.186   8 0.0657 -1.81 -0.33, 0.129 -0.28
C57L/J f -0.145 0.0937   8 0.0331 -0.648 -0.249, 0.004 -0.58
C57L/J m -0.2 0.128   8 0.0453 -0.641 -0.385, -0.002 -0.79
CBA/J f -0.163 0.117   8 0.0413 -0.717 -0.318, -0.02 -0.68
CBA/J m -0.205 0.145   8 0.0513 -0.706 -0.435, 0.012 -0.81
CE/J f -0.107 0.274   8 0.0969 -2.57 -0.68, 0.174 -0.36
CE/J m -0.0159 0.229   9 0.0762 -14.4 -0.514, 0.253 0.17
DBA/1J f -0.0288 0.197   10 0.0625 -6.86 -0.259, 0.343 0.09
DBA/1J m 0.311 0.218   8 0.0772 0.702 -0.025, 0.583 1.88
DBA/2J f 0.0386 0.171   8 0.0604 4.42 -0.22, 0.247 0.48
DBA/2J m -0.0243 0.24   10 0.0758 -9.87 -0.489, 0.216 0.13
FVB/NJ f -0.0812 0.186   8 0.0659 -2.29 -0.304, 0.203 -0.21
FVB/NJ m -0.202 0.207   7 0.0783 -1.03 -0.557, 0.024 -0.8
I/LnJ f 0.00514 0.188   7 0.071 36.5 -0.269, 0.171 0.29
I/LnJ m 0.0344 0.378   5 0.169 11.0 -0.251, 0.651 0.44
KK/HlJ f -0.176 0.187   8 0.066 -1.06 -0.397, 0.123 -0.76
KK/HlJ m -0.232 0.252   6 0.103 -1.08 -0.692, 0.054 -0.95
LP/J f -0.0135 0.332   8 0.117 -24.6 -0.446, 0.663 0.18
LP/J m -0.256 0.18   8 0.0638 -0.704 -0.618, -0.049 -1.08
NOD/ShiLtJ f -0.405 0.235   8 0.0832 -0.58 -0.621, 0.117 -2.07
NOD/ShiLtJ m -0.29 0.392   8 0.139 -1.35 -0.689, 0.421 -1.26
NON/ShiLtJ f 0.131 0.244   8 0.0863 1.86 -0.141, 0.466 1.01
NON/ShiLtJ m 0.0331 0.159   8 0.0561 4.79 -0.325, 0.185 0.43
NZW/LacJ f 0.153 0.175   8 0.0617 1.14 -0.035, 0.433 1.14
NZW/LacJ m -0.0206 0.172   8 0.0609 -8.35 -0.238, 0.318 0.15
PL/J f 0.225 0.232   8 0.082 1.03 -0.055, 0.539 1.56
PL/J m 0.0432 0.299   8 0.106 6.91 -0.449, 0.512 0.48
RIIIS/J f -0.0609 0.198   8 0.07 -3.25 -0.471, 0.061 -0.09
RIIIS/J m 0.0566 0.124   8 0.0438 2.19 -0.176, 0.173 0.55
SJL/J f 0.009 0.311   8 0.11 34.6 -0.345, 0.416 0.31
SJL/J m -0.0109 0.196   8 0.0694 -18.1 -0.209, 0.293 0.2
SM/J f -0.0209 0.19   8 0.0671 -9.1 -0.354, 0.203 0.14
SM/J m 0.0708 0.331   8 0.117 4.68 -0.408, 0.581 0.63
SWR/J f 0.048 0.299   8 0.106 6.23 -0.39, 0.426 0.54
SWR/J m 0.0103 0.103   9 0.0344 9.98 -0.081, 0.195 0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f -0.2498 0.0783 -0.0959 -0.4036
129S1/SvImJ m -0.2232 0.0783 -0.0694 -0.3771
A/J f 0.3364 0.0783 0.4903 0.1825
A/J m 0.4289 0.0783 0.5828 0.275
AKR/J f -0.0214 0.0783 0.1325 -0.1753
AKR/J m -0.2728 0.0783 -0.1189 -0.4266
BALB/cByJ f -0.1179 0.0783 0.036 -0.2718
BALB/cByJ m -0.2008 0.0783 -0.0469 -0.3546
BALB/cJ f -0.1621 0.07 -0.0245 -0.2997
BALB/cJ m -0.135 0.07 0.0026 -0.2726
BTBR T+ Itpr3tf/J f 0.3858 0.0783 0.5396 0.2319
BTBR T+ Itpr3tf/J m 0.4153 0.0783 0.5691 0.2614
BUB/BnJ f -0.0039 0.0837 0.1607 -0.1684
BUB/BnJ m 0.0097 0.0783 0.1636 -0.1441
C3H/HeJ f -0.1 0.0783 0.0539 -0.2539
C3H/HeJ m -0.0029 0.0783 0.151 -0.1568
C57BL/10J f -0.1249 0.0783 0.029 -0.2788
C57BL/10J m 0.0139 0.0837 0.1784 -0.1507
C57BL/6J f -0.2694 0.0837 -0.1049 -0.4339
C57BL/6J m -0.2805 0.0614 -0.1597 -0.4012
C57BLKS/J f -0.2349 0.0668 -0.1037 -0.3661
C57BLKS/J m -0.1795 0.0783 -0.0256 -0.3334
C57BR/cdJ f -0.1503 0.0904 0.0274 -0.328
C57BR/cdJ m -0.1024 0.0783 0.0515 -0.2563
C57L/J f -0.1446 0.0783 0.0093 -0.2985
C57L/J m -0.1996 0.0783 -0.0457 -0.3535
CBA/J f -0.1629 0.0783 -0.009 -0.3168
CBA/J m -0.2054 0.0783 -0.0515 -0.3593
CE/J f -0.1065 0.0783 0.0474 -0.2604
CE/J m -0.0159 0.0738 0.1292 -0.161
DBA/1J f -0.0288 0.07 0.1088 -0.1664
DBA/1J m 0.311 0.0783 0.4649 0.1571
DBA/2J f 0.0386 0.0783 0.1925 -0.1153
DBA/2J m -0.0243 0.07 0.1133 -0.1619
FVB/NJ f -0.0813 0.0783 0.0726 -0.2351
FVB/NJ m -0.2019 0.0837 -0.0373 -0.3664
I/LnJ f 0.0051 0.0837 0.1697 -0.1594
I/LnJ m 0.0344 0.099 0.2291 -0.1603
KK/HlJ f -0.176 0.0783 -0.0221 -0.3299
KK/HlJ m -0.2323 0.0904 -0.0546 -0.41
LP/J f -0.0135 0.0783 0.1404 -0.1674
LP/J m -0.2562 0.0783 -0.1024 -0.4101
NOD/ShiLtJ f -0.4054 0.0783 -0.2515 -0.5593
NOD/ShiLtJ m -0.2899 0.0783 -0.136 -0.4438
NON/ShiLtJ f 0.1312 0.0783 0.2851 -0.0226
NON/ShiLtJ m 0.0331 0.0783 0.187 -0.1208
NZW/LacJ f 0.153 0.0783 0.3069 -0.0009
NZW/LacJ m -0.0206 0.0783 0.1333 -0.1745
PL/J f 0.2251 0.0783 0.379 0.0712
PL/J m 0.0433 0.0783 0.1971 -0.1106
RIIIS/J f -0.0609 0.0783 0.093 -0.2148
RIIIS/J m 0.0566 0.0783 0.2105 -0.0973
SJL/J f 0.009 0.0783 0.1629 -0.1449
SJL/J m -0.0109 0.0783 0.143 -0.1648
SM/J f -0.0209 0.0783 0.133 -0.1748
SM/J m 0.0707 0.0783 0.2246 -0.0831
SWR/J f 0.048 0.0783 0.2019 -0.1059
SWR/J m 0.0103 0.0738 0.1554 -0.1348


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both -0.2365 0.0554 -0.1277 -0.3453
A/J both 0.3826 0.0554 0.4914 0.2738
AKR/J both -0.1471 0.0554 -0.0382 -0.2559
BALB/cByJ both -0.1593 0.0554 -0.0505 -0.2681
BALB/cJ both -0.1486 0.0495 -0.0512 -0.2459
BTBR T+ Itpr3tf/J both 0.4005 0.0554 0.5093 0.2917
BUB/BnJ both 0.0029 0.0573 0.1156 -0.1097
C3H/HeJ both -0.0514 0.0554 0.0574 -0.1603
C57BL/10J both -0.0555 0.0573 0.0571 -0.1681
C57BL/6J both -0.2749 0.0519 -0.1729 -0.377
C57BLKS/J both -0.2072 0.0514 -0.1061 -0.3083
C57BR/cdJ both -0.1264 0.0598 -0.0088 -0.2439
C57L/J both -0.1721 0.0554 -0.0633 -0.2809
CBA/J both -0.1841 0.0554 -0.0753 -0.2929
CE/J both -0.0612 0.0538 0.0446 -0.1669
DBA/1J both 0.1411 0.0525 0.2443 0.0379
DBA/2J both 0.0072 0.0525 0.1104 -0.0961
FVB/NJ both -0.1416 0.0573 -0.0289 -0.2542
I/LnJ both 0.0198 0.0648 0.1472 -0.1077
KK/HlJ both -0.2042 0.0598 -0.0866 -0.3217
LP/J both -0.1349 0.0554 -0.0261 -0.2437
NOD/ShiLtJ both -0.3476 0.0554 -0.2388 -0.4564
NON/ShiLtJ both 0.0822 0.0554 0.191 -0.0266
NZW/LacJ both 0.0662 0.0554 0.175 -0.0426
PL/J both 0.1342 0.0554 0.243 0.0254
RIIIS/J both -0.0021 0.0554 0.1067 -0.1109
SJL/J both -0.0009 0.0554 0.1079 -0.1098
SM/J both 0.0249 0.0554 0.1338 -0.0839
SWR/J both 0.0292 0.0538 0.1349 -0.0766




  GWAS USING LINEAR MIXED MODELS