Project measure / variable:   Berndt2   inspiratory_slope

ID, description, units MPD:35118   inspiratory_slope   inspiratory phase   [s]  response index  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - inspiratory phase response index



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.0941   s 0.107   s
Median of the strain means0.0751   s 0.0735   s
SD of the strain means± 0.116 ± 0.149
Coefficient of variation (CV)1.23 1.40
Min–max range of strain means-0.0838   –   0.458   s -0.109   –   0.507   s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0074 0.0074 0.2785 0.598
strain 28 6.5107 0.2325 8.7868 < 0.0001
sex:strain 28 1.4104 0.0504 1.9035 0.0042
Residuals 412 10.9028 0.0265


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0989 0.139   8 0.0492 1.41 -0.101, 0.298 0.04
129S1/SvImJ m 0.0201 0.182   8 0.0644 9.04 -0.254, 0.278 -0.58
A/J f 0.458 0.14   8 0.0496 0.306 0.262, 0.608 3.13
A/J m 0.507 0.0958   8 0.0339 0.189 0.415, 0.707 2.68
AKR/J f 0.0856 0.116   8 0.041 1.35 -0.125, 0.266 -0.07
AKR/J m -0.109 0.137   8 0.0485 -1.26 -0.346, 0.079 -1.44
BALB/cByJ f 0.115 0.0943   8 0.0334 0.819 -0.033, 0.258 0.18
BALB/cByJ m 0.0249 0.0817   8 0.0289 3.28 -0.051, 0.206 -0.55
BALB/cJ f 0.0567 0.0686   10 0.0217 1.21 -0.041, 0.168 -0.32
BALB/cJ m 0.0583 0.0598   10 0.0189 1.03 -0.028, 0.143 -0.32
BTBR T+ Itpr3tf/J f 0.357 0.236   8 0.0834 0.66 -0.212, 0.506 2.26
BTBR T+ Itpr3tf/J m 0.347 0.122   8 0.043 0.351 0.206, 0.589 1.61
BUB/BnJ f 0.091 0.248   7 0.0937 2.72 -0.399, 0.309 -0.03
BUB/BnJ m 0.132 0.185   8 0.0655 1.41 -0.107, 0.371 0.17
C3H/HeJ f 0.0346 0.263   8 0.0931 7.6 -0.313, 0.407 -0.51
C3H/HeJ m 0.126 0.186   8 0.0657 1.47 -0.162, 0.429 0.13
C57BL/10J f 0.00888 0.0653   8 0.0231 7.36 -0.099, 0.14 -0.73
C57BL/10J m 0.14 0.125   7 0.0472 0.891 0.024, 0.354 0.22
C57BL/6J f 0.0517 0.0668   7 0.0253 1.29 -0.063, 0.142 -0.37
C57BL/6J m 0.0114 0.0809   13 0.0224 7.11 -0.186, 0.122 -0.64
C57BLKS/J f 0.0815 0.114   11 0.0344 1.4 -0.063, 0.308 -0.11
C57BLKS/J m 0.197 0.216   8 0.0762 1.09 -0.222, 0.425 0.61
C57BR/cdJ f -0.0382 0.115   6 0.0469 -3.01 -0.219, 0.124 -1.14
C57BR/cdJ m 0.0364 0.0929   8 0.0328 2.55 -0.07, 0.174 -0.47
C57L/J f 0.0479 0.0917   8 0.0324 1.92 -0.056, 0.254 -0.4
C57L/J m 0.133 0.0815   8 0.0288 0.613 0.032, 0.276 0.18
CBA/J f 0.0816 0.0635   8 0.0224 0.778 -0.003, 0.202 -0.11
CBA/J m 0.00937 0.131   8 0.0463 14.0 -0.203, 0.183 -0.65
CE/J f 0.0646 0.219   8 0.0776 3.4 -0.425, 0.298 -0.25
CE/J m 0.0931 0.203   9 0.0676 2.18 -0.181, 0.36 -0.09
DBA/1J f -0.0408 0.156   10 0.0492 -3.82 -0.239, 0.285 -1.16
DBA/1J m 0.355 0.0659   8 0.0233 0.185 0.253, 0.448 1.66
DBA/2J f 0.0826 0.132   8 0.0466 1.59 -0.098, 0.306 -0.1
DBA/2J m 0.0055 0.209   10 0.0659 37.9 -0.365, 0.259 -0.68
FVB/NJ f -0.00738 0.251   8 0.0888 -34.1 -0.392, 0.328 -0.87
FVB/NJ m -0.0139 0.152   7 0.0573 -10.9 -0.214, 0.246 -0.81
I/LnJ f 0.174 0.281   7 0.106 1.61 -0.157, 0.533 0.69
I/LnJ m 0.321 0.265   5 0.118 0.825 0.048, 0.687 1.44
KK/HlJ f 0.0751 0.161   8 0.0571 2.15 -0.125, 0.337 -0.16
KK/HlJ m 0.0572 0.181   6 0.0741 3.17 -0.125, 0.325 -0.33
LP/J f 0.0561 0.139   8 0.0492 2.48 -0.16, 0.273 -0.33
LP/J m -0.0444 0.16   8 0.0565 -3.6 -0.324, 0.172 -1.01
NOD/ShiLtJ f -0.0838 0.133   8 0.0469 -1.58 -0.249, 0.158 -1.53
NOD/ShiLtJ m -0.0676 0.135   8 0.0476 -1.99 -0.226, 0.107 -1.17
NON/ShiLtJ f 0.29 0.211   8 0.0746 0.728 0.025, 0.657 1.69
NON/ShiLtJ m 0.292 0.118   8 0.0418 0.404 0.146, 0.463 1.24
NZW/LacJ f 0.0575 0.133   8 0.0469 2.31 -0.191, 0.227 -0.32
NZW/LacJ m -0.1 0.129   8 0.0455 -1.29 -0.281, 0.067 -1.38
PL/J f 0.191 0.0936   8 0.0331 0.49 0.027, 0.297 0.83
PL/J m 0.133 0.231   8 0.0817 1.73 -0.322, 0.387 0.18
RIIIS/J f 0.0478 0.136   8 0.048 2.84 -0.266, 0.168 -0.4
RIIIS/J m 0.0735 0.133   8 0.0469 1.8 -0.164, 0.193 -0.22
SJL/J f -0.00425 0.247   8 0.0874 -58.2 -0.391, 0.281 -0.85
SJL/J m -0.0239 0.197   8 0.0698 -8.26 -0.243, 0.374 -0.87
SM/J f 0.2 0.0637   8 0.0225 0.318 0.069, 0.277 0.91
SM/J m 0.264 0.174   8 0.0617 0.66 0.05, 0.518 1.05
SWR/J f 0.0971 0.369   8 0.13 3.8 -0.347, 0.565 0.03
SWR/J m 0.114 0.127   9 0.0424 1.11 -0.031, 0.342 0.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0989 0.0575 0.2119 -0.0142
129S1/SvImJ m 0.0201 0.0575 0.1332 -0.0929
A/J f 0.4578 0.0575 0.5708 0.3447
A/J m 0.5074 0.0575 0.6204 0.3943
AKR/J f 0.0856 0.0575 0.1987 -0.0274
AKR/J m -0.1086 0.0575 0.0044 -0.2217
BALB/cByJ f 0.1152 0.0575 0.2283 0.0022
BALB/cByJ m 0.0249 0.0575 0.1379 -0.0882
BALB/cJ f 0.0567 0.0514 0.1578 -0.0444
BALB/cJ m 0.0583 0.0514 0.1594 -0.0428
BTBR T+ Itpr3tf/J f 0.3574 0.0575 0.4704 0.2443
BTBR T+ Itpr3tf/J m 0.3465 0.0575 0.4596 0.2334
BUB/BnJ f 0.091 0.0615 0.2119 -0.0299
BUB/BnJ m 0.1316 0.0575 0.2447 0.0186
C3H/HeJ f 0.0346 0.0575 0.1477 -0.0784
C3H/HeJ m 0.1264 0.0575 0.2394 0.0133
C57BL/10J f 0.0089 0.0575 0.1219 -0.1042
C57BL/10J m 0.1403 0.0615 0.2611 0.0194
C57BL/6J f 0.0517 0.0615 0.1726 -0.0691
C57BL/6J m 0.0114 0.0451 0.1001 -0.0773
C57BLKS/J f 0.0815 0.049 0.1779 -0.015
C57BLKS/J m 0.197 0.0575 0.3101 0.0839
C57BR/cdJ f -0.0382 0.0664 0.0924 -0.1687
C57BR/cdJ m 0.0364 0.0575 0.1494 -0.0767
C57L/J f 0.0479 0.0575 0.1609 -0.0652
C57L/J m 0.1329 0.0575 0.2459 0.0198
CBA/J f 0.0816 0.0575 0.1947 -0.0314
CBA/J m 0.0094 0.0575 0.1224 -0.1037
CE/J f 0.0646 0.0575 0.1777 -0.0484
CE/J m 0.0931 0.0542 0.1997 -0.0135
DBA/1J f -0.0408 0.0514 0.0603 -0.1419
DBA/1J m 0.3551 0.0575 0.4682 0.2421
DBA/2J f 0.0826 0.0575 0.1957 -0.0304
DBA/2J m 0.0055 0.0514 0.1066 -0.0956
FVB/NJ f -0.0074 0.0575 0.1057 -0.1204
FVB/NJ m -0.0139 0.0615 0.107 -0.1347
I/LnJ f 0.1743 0.0615 0.2951 0.0534
I/LnJ m 0.3212 0.0728 0.4642 0.1782
KK/HlJ f 0.0751 0.0575 0.1882 -0.0379
KK/HlJ m 0.0572 0.0664 0.1877 -0.0734
LP/J f 0.0561 0.0575 0.1692 -0.0569
LP/J m -0.0444 0.0575 0.0687 -0.1574
NOD/ShiLtJ f -0.0838 0.0575 0.0293 -0.1968
NOD/ShiLtJ m -0.0676 0.0575 0.0454 -0.1807
NON/ShiLtJ f 0.2897 0.0575 0.4028 0.1767
NON/ShiLtJ m 0.2925 0.0575 0.4056 0.1794
NZW/LacJ f 0.0575 0.0575 0.1706 -0.0556
NZW/LacJ m -0.1 0.0575 0.0131 -0.2131
PL/J f 0.1912 0.0575 0.3043 0.0782
PL/J m 0.1334 0.0575 0.2464 0.0203
RIIIS/J f 0.0477 0.0575 0.1608 -0.0653
RIIIS/J m 0.0735 0.0575 0.1866 -0.0396
SJL/J f -0.0043 0.0575 0.1088 -0.1173
SJL/J m -0.0239 0.0575 0.0892 -0.1369
SM/J f 0.2004 0.0575 0.3134 0.0873
SM/J m 0.2644 0.0575 0.3774 0.1513
SWR/J f 0.0971 0.0575 0.2102 -0.0159
SWR/J m 0.114 0.0542 0.2206 0.0074


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0595 0.0407 0.1394 -0.0204
A/J both 0.4826 0.0407 0.5625 0.4026
AKR/J both -0.0115 0.0407 0.0684 -0.0914
BALB/cByJ both 0.0701 0.0407 0.15 -0.0099
BALB/cJ both 0.0575 0.0364 0.129 -0.014
BTBR T+ Itpr3tf/J both 0.3519 0.0407 0.4319 0.272
BUB/BnJ both 0.1113 0.0421 0.1941 0.0286
C3H/HeJ both 0.0805 0.0407 0.1604 0.0006
C57BL/10J both 0.0746 0.0421 0.1573 -0.0082
C57BL/6J both 0.0315 0.0381 0.1065 -0.0434
C57BLKS/J both 0.1392 0.0378 0.2135 0.0649
C57BR/cdJ both -0.0009 0.0439 0.0855 -0.0872
C57L/J both 0.0904 0.0407 0.1703 0.0104
CBA/J both 0.0455 0.0407 0.1254 -0.0344
CE/J both 0.0789 0.0395 0.1566 0.0012
DBA/1J both 0.1572 0.0386 0.233 0.0813
DBA/2J both 0.0441 0.0386 0.1199 -0.0318
FVB/NJ both -0.0106 0.0421 0.0721 -0.0934
I/LnJ both 0.2477 0.0476 0.3414 0.1541
KK/HlJ both 0.0661 0.0439 0.1525 -0.0202
LP/J both 0.0059 0.0407 0.0858 -0.0741
NOD/ShiLtJ both -0.0757 0.0407 0.0043 -0.1556
NON/ShiLtJ both 0.2911 0.0407 0.3711 0.2112
NZW/LacJ both -0.0213 0.0407 0.0587 -0.1012
PL/J both 0.1623 0.0407 0.2423 0.0824
RIIIS/J both 0.0606 0.0407 0.1406 -0.0193
SJL/J both -0.0141 0.0407 0.0659 -0.094
SM/J both 0.2324 0.0407 0.3123 0.1524
SWR/J both 0.1056 0.0395 0.1833 0.0279




  GWAS USING LINEAR MIXED MODELS