Project measure / variable:   Berndt1   airway_res_mch10

ID, description, units MPD:34213   airway_res_mch10   airway resistance (H2O pressure)   [cm/mL/s]  MCh challenge 10 mg/mL  
methacholine study
Data set, strains Berndt1   inbred   37 strains     sex: both     age: 9-12wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Berndt1 - airway resistance (H2O pressure) MCh challenge 10 mg/mL



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested36 strains33 strains
Mean of the strain means1.08   cm/mL/s 1.24   cm/mL/s
Median of the strain means1.14   cm/mL/s 1.27   cm/mL/s
SD of the strain means± 0.351 ± 0.330
Coefficient of variation (CV)0.326 0.267
Min–max range of strain means0.539   –   2.28   cm/mL/s 0.639   –   2.08   cm/mL/s
Mean sample size per strain8.5   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.9073 4.9073 36.2028 < 0.0001
strain 31 50.9931 1.6449 12.1353 < 0.0001
sex:strain 31 11.6293 0.3751 2.7675 < 0.0001
Residuals 504 68.3174 0.1356


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.612 0.102   9 0.0339 0.166 0.48, 0.79 -1.32
129S1/SvImJ m 0.78 0.379   8 0.134 0.486 0.48, 1.68 -1.38
A/J f 1.42 0.444   10 0.14 0.313 0.84, 2.29 0.98
A/J m 1.78 0.574   9 0.191 0.322 0.79, 2.61 1.65
AKR/J f 1.01 0.198   9 0.066 0.196 0.74, 1.31 -0.19
AKR/J m 1.59 0.343   8 0.121 0.216 0.99, 2.05 1.07
BALB/cByJ f 1.01 0.493   8 0.174 0.488 0.54, 1.91 -0.19
BALB/cByJ m 1.42 0.672   8 0.238 0.472 0.79, 2.69 0.56
BALB/cJ f 0.982 0.0963   8 0.0341 0.098 0.85, 1.12 -0.27
BALB/cJ m 1.42 0.495   10 0.157 0.349 0.82, 2.49 0.56
BPN/3J f 0.704 0.283   8 0.0999 0.401 0.4, 1.3 -1.06
BTBR T+ Itpr3tf/J f 1.31 0.338   10 0.107 0.258 0.64, 1.82 0.66
BTBR T+ Itpr3tf/J m 1.34 0.348   10 0.11 0.26 0.86, 1.9 0.31
BUB/BnJ f 1.39 0.195   9 0.0651 0.141 1.06, 1.64 0.89
BUB/BnJ m 1.39 0.475   10 0.15 0.341 0.66, 2.32 0.47
C3H/HeJ f 1.2 0.285   10 0.0901 0.237 0.75, 1.59 0.35
C3H/HeJ m 1.28 0.206   9 0.0688 0.162 0.84, 1.53 0.13
C57BL/10J f 0.724 0.15   9 0.0501 0.208 0.57, 1.05 -1.0
C57BL/10J m 1.06 0.167   10 0.0527 0.157 0.86, 1.42 -0.53
C57BL/6J f 0.539 0.172   8 0.0606 0.318 0.32, 0.81 -1.53
C57BL/6J m 1.08 0.283   8 0.0999 0.263 0.59, 1.41 -0.47
C57BLKS/J f 0.866 0.188   9 0.0626 0.217 0.65, 1.17 -0.6
C57BLKS/J m 1.35 0.423   12 0.122 0.312 0.68, 2.01 0.34
C57BR/cdJ f 1.22 0.534   6 0.218 0.44 0.72, 2.2 0.41
C57BR/cdJ m 1.27 0.535   10 0.169 0.42 0.64, 2.57 0.1
C57L/J f 1.24 0.546   6 0.223 0.439 0.81, 2.09 0.46
C57L/J m 1.02 0.303   10 0.0958 0.298 0.51, 1.42 -0.66
CBA/J f 1.13 0.402   8 0.142 0.356 0.79, 2.03 0.15
CBA/J m 1.07 0.34   10 0.108 0.319 0.73, 1.94 -0.5
CE/J f 1.25 0.276   9 0.0921 0.22 0.93, 1.7 0.49
CE/J m 1.14 0.283   9 0.0943 0.247 0.74, 1.7 -0.29
DBA/1J f 1.43 0.391   9 0.13 0.273 0.81, 2.0 1.0
DBA/1J m 1.47 0.619   10 0.196 0.422 0.65, 2.48 0.71
DBA/2J f 0.9 0.239   10 0.0755 0.265 0.63, 1.33 -0.5
DBA/2J m 1.32 0.302   10 0.0955 0.229 0.98, 1.88 0.25
FVB/NJ f 1.15 0.311   10 0.0984 0.271 0.44, 1.5 0.21
FVB/NJ m 1.32 0.856   10 0.271 0.648 0.38, 2.76 0.25
I/LnJ f 1.57 0.315   5 0.141 0.201 1.16, 2.03 1.4
I/LnJ m 1.57 0.511   8 0.181 0.324 0.65, 2.16 1.01
KK/HlJ f 2.28 0.635   9 0.212 0.278 1.21, 3.31 3.42
KK/HlJ m 2.08 0.532   10 0.168 0.255 1.36, 2.84 2.56
LG/J f 0.685 0.174   10 0.055 0.254 0.44, 1.08 -1.12
LG/J m 0.776 0.211   10 0.0666 0.271 0.56, 1.22 -1.4
LP/J f 0.622 0.118   9 0.0394 0.19 0.47, 0.84 -1.29
LP/J m 1.32 0.226   10 0.0714 0.172 1.09, 1.8 0.25
MA/MyJ f 1.56 0.458   9 0.153 0.293 0.93, 2.26 1.37
MRL/MpJ f 1.23 0.439   9 0.146 0.357 0.86, 1.98 0.44
MRL/MpJ m 0.906 0.277   9 0.0923 0.306 0.53, 1.29 -1.0
NOD/ShiLtJ f 0.884 0.183   9 0.0611 0.207 0.5, 1.16 -0.55
NOD/ShiLtJ m 1.65 0.561   9 0.187 0.34 0.95, 2.46 1.25
NON/ShiLtJ f 1.2 0.112   7 0.0425 0.0938 1.0, 1.32 0.35
NON/ShiLtJ m 1.06 0.191   7 0.0723 0.181 0.72, 1.24 -0.53
NZB/BlNJ m 0.639 0.222   10 0.0703 0.348 0.35, 1.18 -1.81
NZO/HlLtJ f 1.22 0.217   9 0.0724 0.178 0.89, 1.59 0.41
NZW/LacJ f 0.684 0.195   8 0.069 0.286 0.44, 0.99 -1.12
NZW/LacJ m 0.739 0.219   10 0.0692 0.296 0.46, 1.09 -1.51
P/J f 0.853 0.174   7 0.0658 0.204 0.63, 1.08 -0.64
P/J m 1.05 0.432   8 0.153 0.409 0.67, 1.96 -0.56
PL/J f 1.19 0.28   9 0.0935 0.235 0.7, 1.69 0.32
PL/J m 1.74 0.267   8 0.0943 0.153 1.28, 2.16 1.53
PWD/PhJ f 0.933 0.253   6 0.103 0.271 0.58, 1.27 -0.41
RIIIS/J f 1.2 0.264   6 0.108 0.221 0.88, 1.56 0.35
RIIIS/J m 0.931 0.279   9 0.0929 0.299 0.54, 1.36 -0.93
SJL/J f 0.689 0.104   8 0.0369 0.151 0.56, 0.87 -1.1
SJL/J m 1.23 0.456   9 0.152 0.372 0.66, 1.87 -0.02
SM/J f 1.21 0.288   10 0.0912 0.238 0.89, 1.74 0.38
SM/J m 1.2 0.216   8 0.0762 0.18 0.88, 1.45 -0.11
SWR/J f 0.673 0.13   9 0.0434 0.193 0.49, 0.89 -1.15
SWR/J m 0.805 0.272   10 0.0861 0.338 0.53, 1.27 -1.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6122 0.1227 0.8533 0.3711
129S1/SvImJ m 0.78 0.1302 1.0357 0.5243
A/J f 1.419 0.1164 1.6477 1.1903
A/J m 1.7789 0.1227 2.02 1.5378
AKR/J f 1.0111 0.1227 1.2522 0.77
AKR/J m 1.5938 0.1302 1.8495 1.338
BALB/cByJ f 1.01 0.1302 1.2657 0.7543
BALB/cByJ m 1.4225 0.1302 1.6782 1.1668
BALB/cJ f 0.9825 0.1302 1.2382 0.7268
BALB/cJ m 1.417 0.1164 1.6457 1.1883
BTBR T+ Itpr3tf/J f 1.31 0.1164 1.5387 1.0813
BTBR T+ Itpr3tf/J m 1.339 0.1164 1.5677 1.1103
BUB/BnJ f 1.3856 0.1227 1.6267 1.1444
BUB/BnJ m 1.393 0.1164 1.6217 1.1643
C3H/HeJ f 1.203 0.1164 1.4317 0.9743
C3H/HeJ m 1.2767 0.1227 1.5178 1.0356
C57BL/10J f 0.7244 0.1227 0.9656 0.4833
C57BL/10J m 1.062 0.1164 1.2907 0.8333
C57BL/6J f 0.5387 0.1302 0.7945 0.283
C57BL/6J m 1.0762 0.1302 1.332 0.8205
C57BLKS/J f 0.8656 0.1227 1.1067 0.6244
C57BLKS/J m 1.355 0.1063 1.5638 1.1462
C57BR/cdJ f 1.215 0.1503 1.5103 0.9197
C57BR/cdJ m 1.274 0.1164 1.5027 1.0453
C57L/J f 1.2433 0.1503 1.5386 0.948
C57L/J m 1.017 0.1164 1.2457 0.7883
CBA/J f 1.1275 0.1302 1.3832 0.8718
CBA/J m 1.066 0.1164 1.2947 0.8373
CE/J f 1.2544 0.1227 1.4956 1.0133
CE/J m 1.1444 0.1227 1.3856 0.9033
DBA/1J f 1.4322 0.1227 1.6733 1.1911
DBA/1J m 1.466 0.1164 1.6947 1.2373
DBA/2J f 0.9 0.1164 1.1287 0.6713
DBA/2J m 1.318 0.1164 1.5467 1.0893
FVB/NJ f 1.149 0.1164 1.3777 0.9203
FVB/NJ m 1.321 0.1164 1.5497 1.0923
I/LnJ f 1.566 0.1647 1.8895 1.2425
I/LnJ m 1.575 0.1302 1.8307 1.3193
KK/HlJ f 2.2822 0.1227 2.5233 2.0411
KK/HlJ m 2.085 0.1164 2.3137 1.8563
LG/J f 0.685 0.1164 0.9137 0.4563
LG/J m 0.776 0.1164 1.0047 0.5473
LP/J f 0.6222 0.1227 0.8633 0.3811
LP/J m 1.317 0.1164 1.5457 1.0883
MRL/MpJ f 1.2289 0.1227 1.47 0.9878
MRL/MpJ m 0.9056 0.1227 1.1467 0.6644
NOD/ShiLtJ f 0.8844 0.1227 1.1256 0.6433
NOD/ShiLtJ m 1.6478 0.1227 1.8889 1.4067
NON/ShiLtJ f 1.1986 0.1392 1.472 0.9252
NON/ShiLtJ m 1.0571 0.1392 1.3305 0.7837
NZW/LacJ f 0.6837 0.1302 0.9395 0.428
NZW/LacJ m 0.739 0.1164 0.9677 0.5103
P/J f 0.8529 0.1392 1.1263 0.5795
P/J m 1.055 0.1302 1.3107 0.7993
PL/J f 1.1911 0.1227 1.4322 0.95
PL/J m 1.7425 0.1302 1.9982 1.4868
RIIIS/J f 1.195 0.1503 1.4903 0.8997
RIIIS/J m 0.9311 0.1227 1.1722 0.69
SJL/J f 0.6887 0.1302 0.9445 0.433
SJL/J m 1.2256 0.1227 1.4667 0.9844
SM/J f 1.211 0.1164 1.4397 0.9823
SM/J m 1.2 0.1302 1.4557 0.9443
SWR/J f 0.6733 0.1227 0.9144 0.4322
SWR/J m 0.805 0.1164 1.0337 0.5763


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.6961 0.0894 0.8719 0.5204
A/J both 1.5989 0.0846 1.7651 1.4328
AKR/J both 1.3024 0.0894 1.4782 1.1267
BALB/cByJ both 1.2163 0.092 1.3971 1.0354
BALB/cJ both 1.1998 0.0873 1.3713 1.0282
BTBR T+ Itpr3tf/J both 1.3245 0.0823 1.4862 1.1628
BUB/BnJ both 1.3893 0.0846 1.5555 1.2231
C3H/HeJ both 1.2398 0.0846 1.406 1.0737
C57BL/10J both 0.8932 0.0846 1.0594 0.727
C57BL/6J both 0.8075 0.092 0.9883 0.6267
C57BLKS/J both 1.1103 0.0812 1.2698 0.9508
C57BR/cdJ both 1.2445 0.0951 1.4313 1.0577
C57L/J both 1.1302 0.0951 1.3169 0.9434
CBA/J both 1.0967 0.0873 1.2683 0.9252
CE/J both 1.1994 0.0868 1.3699 1.029
DBA/1J both 1.4491 0.0846 1.6153 1.2829
DBA/2J both 1.109 0.0823 1.2707 0.9473
FVB/NJ both 1.235 0.0823 1.3967 1.0733
I/LnJ both 1.5705 0.1049 1.7767 1.3643
KK/HlJ both 2.1836 0.0846 2.3498 2.0174
LG/J both 0.7305 0.0823 0.8922 0.5688
LP/J both 0.9696 0.0846 1.1358 0.8034
MRL/MpJ both 1.0672 0.0868 1.2377 0.8967
NOD/ShiLtJ both 1.2661 0.0868 1.4366 1.0956
NON/ShiLtJ both 1.1279 0.0984 1.3212 0.9345
NZW/LacJ both 0.7114 0.0873 0.8829 0.5398
P/J both 0.9539 0.0953 1.1411 0.7667
PL/J both 1.4668 0.0894 1.6425 1.2911
RIIIS/J both 1.0631 0.097 1.2537 0.8724
SJL/J both 0.9572 0.0894 1.1329 0.7814
SM/J both 1.2055 0.0873 1.3771 1.0339
SWR/J both 0.7392 0.0846 0.9053 0.573




  GWAS USING LINEAR MIXED MODELS