Project measure / variable:   Berndt1   airway_res_mch1

ID, description, units MPD:34211   airway_res_mch1   airway resistance (H2O pressure)   [cm/mL/s]  MCh challenge 1 mg/mL  
methacholine study
Data set, strains Berndt1   inbred   37 strains     sex: both     age: 9-12wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Berndt1 - airway resistance (H2O pressure) MCh challenge 1 mg/mL



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested36 strains33 strains
Mean of the strain means0.496   cm/mL/s 0.535   cm/mL/s
Median of the strain means0.530   cm/mL/s 0.544   cm/mL/s
SD of the strain means± 0.126 ± 0.128
Coefficient of variation (CV)0.254 0.240
Min–max range of strain means0.283   –   0.751   cm/mL/s 0.333   –   0.889   cm/mL/s
Mean sample size per strain8.6   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1634 0.1634 8.5885 0.0035
strain 31 6.8284 0.2203 11.5791 < 0.0001
sex:strain 31 2.0901 0.0674 3.5443 < 0.0001
Residuals 509 9.6828 0.019


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.283 0.0339   9 0.0113 0.12 0.24, 0.33 -1.69
129S1/SvImJ m 0.333 0.0907   8 0.0321 0.273 0.21, 0.5 -1.58
A/J f 0.585 0.159   10 0.0503 0.272 0.4, 0.85 0.71
A/J m 0.794 0.17   9 0.0567 0.214 0.54, 1.03 2.02
AKR/J f 0.573 0.144   9 0.0482 0.252 0.32, 0.79 0.61
AKR/J m 0.889 0.269   8 0.0952 0.303 0.51, 1.35 2.76
BALB/cByJ f 0.506 0.107   8 0.0379 0.212 0.4, 0.73 0.08
BALB/cByJ m 0.645 0.19   8 0.067 0.294 0.42, 0.93 0.85
BALB/cJ f 0.606 0.254   8 0.0898 0.419 0.43, 1.21 0.87
BALB/cJ m 0.629 0.114   10 0.0359 0.181 0.43, 0.79 0.73
BPN/3J f 0.375 0.112   8 0.0395 0.298 0.25, 0.53 -0.96
BTBR T+ Itpr3tf/J f 0.535 0.161   10 0.051 0.301 0.31, 0.78 0.31
BTBR T+ Itpr3tf/J m 0.508 0.111   10 0.0352 0.219 0.4, 0.78 -0.21
BUB/BnJ f 0.751 0.177   9 0.0589 0.235 0.52, 1.1 2.02
BUB/BnJ m 0.565 0.127   10 0.04 0.224 0.42, 0.81 0.23
C3H/HeJ f 0.638 0.176   10 0.0557 0.276 0.43, 0.94 1.13
C3H/HeJ m 0.647 0.173   9 0.0578 0.268 0.47, 1.02 0.87
C57BL/10J f 0.309 0.0404   9 0.0135 0.131 0.27, 0.41 -1.49
C57BL/10J m 0.387 0.0462   10 0.0146 0.119 0.3, 0.43 -1.16
C57BL/6J f 0.354 0.0847   8 0.0299 0.239 0.25, 0.46 -1.13
C57BL/6J m 0.621 0.209   8 0.0737 0.336 0.36, 1.04 0.67
C57BLKS/J f 0.3 0.0522   9 0.0174 0.174 0.22, 0.37 -1.56
C57BLKS/J m 0.403 0.096   12 0.0277 0.238 0.27, 0.55 -1.03
C57BR/cdJ f 0.531 0.172   7 0.0652 0.324 0.31, 0.71 0.28
C57BR/cdJ m 0.457 0.0897   10 0.0284 0.196 0.36, 0.62 -0.61
C57L/J f 0.482 0.165   6 0.0672 0.342 0.26, 0.67 -0.11
C57L/J m 0.435 0.0752   10 0.0238 0.173 0.29, 0.58 -0.78
CBA/J f 0.661 0.106   8 0.0376 0.161 0.52, 0.85 1.31
CBA/J m 0.522 0.0794   10 0.0251 0.152 0.43, 0.65 -0.1
CE/J f 0.544 0.168   9 0.0559 0.308 0.36, 0.86 0.38
CE/J m 0.594 0.104   9 0.0348 0.175 0.43, 0.74 0.46
DBA/1J f 0.556 0.153   9 0.0511 0.276 0.35, 0.87 0.47
DBA/1J m 0.494 0.102   10 0.0323 0.206 0.33, 0.68 -0.32
DBA/2J f 0.411 0.0703   10 0.0222 0.171 0.31, 0.54 -0.68
DBA/2J m 0.557 0.0615   10 0.0194 0.11 0.48, 0.63 0.17
FVB/NJ f 0.567 0.161   10 0.051 0.284 0.27, 0.88 0.56
FVB/NJ m 0.431 0.198   10 0.0625 0.459 0.18, 0.77 -0.81
I/LnJ f 0.617 0.104   9 0.0348 0.169 0.42, 0.74 0.96
I/LnJ m 0.586 0.0962   8 0.034 0.164 0.44, 0.71 0.39
KK/HlJ f 0.537 0.122   9 0.0408 0.228 0.38, 0.72 0.32
KK/HlJ m 0.496 0.0412   10 0.013 0.083 0.44, 0.57 -0.31
LG/J f 0.393 0.0685   10 0.0217 0.174 0.32, 0.54 -0.82
LG/J m 0.46 0.0942   10 0.0298 0.205 0.31, 0.57 -0.59
LP/J f 0.297 0.04   9 0.0133 0.135 0.23, 0.34 -1.58
LP/J m 0.388 0.0449   10 0.0142 0.116 0.33, 0.46 -1.15
MA/MyJ f 0.479 0.0389   9 0.013 0.0812 0.43, 0.55 -0.14
MRL/MpJ f 0.556 0.123   9 0.0411 0.222 0.35, 0.7 0.47
MRL/MpJ m 0.559 0.125   9 0.0416 0.223 0.42, 0.81 0.18
NOD/ShiLtJ f 0.421 0.152   9 0.0508 0.362 0.25, 0.77 -0.6
NOD/ShiLtJ m 0.621 0.118   9 0.0395 0.191 0.43, 0.79 0.67
NON/ShiLtJ f 0.677 0.207   7 0.0781 0.305 0.49, 0.98 1.44
NON/ShiLtJ m 0.6 0.271   7 0.102 0.451 0.42, 1.19 0.5
NZB/BlNJ m 0.384 0.0942   10 0.0298 0.245 0.21, 0.56 -1.18
NZO/HlLtJ f 0.576 0.142   9 0.0473 0.246 0.36, 0.82 0.63
NZW/LacJ f 0.368 0.0819   8 0.029 0.223 0.25, 0.51 -1.02
NZW/LacJ m 0.346 0.0566   10 0.0179 0.164 0.26, 0.45 -1.48
P/J f 0.529 0.122   7 0.046 0.23 0.4, 0.69 0.26
P/J m 0.601 0.233   8 0.0825 0.388 0.39, 1.06 0.51
PL/J f 0.491 0.137   9 0.0458 0.28 0.3, 0.68 -0.04
PL/J m 0.749 0.115   8 0.0408 0.154 0.61, 0.99 1.66
PWD/PhJ f 0.38 0.11   6 0.0451 0.291 0.24, 0.54 -0.92
RIIIS/J f 0.718 0.389   6 0.159 0.541 0.34, 1.4 1.76
RIIIS/J m 0.571 0.171   9 0.0569 0.299 0.33, 0.91 0.28
SJL/J f 0.409 0.113   8 0.0401 0.278 0.32, 0.67 -0.69
SJL/J m 0.454 0.0847   9 0.0282 0.186 0.33, 0.57 -0.63
SM/J f 0.543 0.143   10 0.0451 0.262 0.42, 0.86 0.37
SM/J m 0.544 0.0737   8 0.026 0.135 0.41, 0.64 0.07
SWR/J f 0.307 0.0602   9 0.0201 0.196 0.23, 0.41 -1.5
SWR/J m 0.396 0.118   10 0.0373 0.298 0.3, 0.69 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2833 0.046 0.3737 0.193
129S1/SvImJ m 0.3325 0.0488 0.4283 0.2367
A/J f 0.585 0.0436 0.6707 0.4993
A/J m 0.7944 0.046 0.8848 0.7041
AKR/J f 0.5733 0.046 0.6637 0.483
AKR/J m 0.8888 0.0488 0.9846 0.7929
BALB/cByJ f 0.5062 0.0488 0.6021 0.4104
BALB/cByJ m 0.645 0.0488 0.7408 0.5492
BALB/cJ f 0.6062 0.0488 0.7021 0.5104
BALB/cJ m 0.629 0.0436 0.7147 0.5433
BTBR T+ Itpr3tf/J f 0.535 0.0436 0.6207 0.4493
BTBR T+ Itpr3tf/J m 0.508 0.0436 0.5937 0.4223
BUB/BnJ f 0.7511 0.046 0.8414 0.6608
BUB/BnJ m 0.565 0.0436 0.6507 0.4793
C3H/HeJ f 0.638 0.0436 0.7237 0.5523
C3H/HeJ m 0.6467 0.046 0.737 0.5563
C57BL/10J f 0.3089 0.046 0.3992 0.2186
C57BL/10J m 0.387 0.0436 0.4727 0.3013
C57BL/6J f 0.3537 0.0488 0.4496 0.2579
C57BL/6J m 0.6212 0.0488 0.7171 0.5254
C57BLKS/J f 0.3 0.046 0.3903 0.2097
C57BLKS/J m 0.4033 0.0398 0.4816 0.3251
C57BR/cdJ f 0.5314 0.0521 0.6338 0.429
C57BR/cdJ m 0.457 0.0436 0.5427 0.3713
C57L/J f 0.4817 0.0563 0.5923 0.371
C57L/J m 0.435 0.0436 0.5207 0.3493
CBA/J f 0.6612 0.0488 0.7571 0.5654
CBA/J m 0.522 0.0436 0.6077 0.4363
CE/J f 0.5444 0.046 0.6348 0.4541
CE/J m 0.5944 0.046 0.6848 0.5041
DBA/1J f 0.5556 0.046 0.6459 0.4652
DBA/1J m 0.494 0.0436 0.5797 0.4083
DBA/2J f 0.411 0.0436 0.4967 0.3253
DBA/2J m 0.557 0.0436 0.6427 0.4713
FVB/NJ f 0.567 0.0436 0.6527 0.4813
FVB/NJ m 0.431 0.0436 0.5167 0.3453
I/LnJ f 0.6167 0.046 0.707 0.5263
I/LnJ m 0.5862 0.0488 0.6821 0.4904
KK/HlJ f 0.5367 0.046 0.627 0.4463
KK/HlJ m 0.496 0.0436 0.5817 0.4103
LG/J f 0.393 0.0436 0.4787 0.3073
LG/J m 0.46 0.0436 0.5457 0.3743
LP/J f 0.2967 0.046 0.387 0.2063
LP/J m 0.388 0.0436 0.4737 0.3023
MRL/MpJ f 0.5556 0.046 0.6459 0.4652
MRL/MpJ m 0.5589 0.046 0.6492 0.4686
NOD/ShiLtJ f 0.4211 0.046 0.5114 0.3308
NOD/ShiLtJ m 0.6211 0.046 0.7114 0.5308
NON/ShiLtJ f 0.6771 0.0521 0.7796 0.5747
NON/ShiLtJ m 0.6 0.0521 0.7024 0.4976
NZW/LacJ f 0.3675 0.0488 0.4633 0.2717
NZW/LacJ m 0.346 0.0436 0.4317 0.2603
P/J f 0.5286 0.0521 0.631 0.4262
P/J m 0.6012 0.0488 0.6971 0.5054
PL/J f 0.4911 0.046 0.5814 0.4008
PL/J m 0.7488 0.0488 0.8446 0.6529
RIIIS/J f 0.7183 0.0563 0.829 0.6077
RIIIS/J m 0.5711 0.046 0.6614 0.4808
SJL/J f 0.4088 0.0488 0.5046 0.3129
SJL/J m 0.4544 0.046 0.5448 0.3641
SM/J f 0.543 0.0436 0.6287 0.4573
SM/J m 0.5437 0.0488 0.6396 0.4479
SWR/J f 0.3067 0.046 0.397 0.2163
SWR/J m 0.396 0.0436 0.4817 0.3103


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3079 0.0335 0.3738 0.2421
A/J both 0.6897 0.0317 0.752 0.6275
AKR/J both 0.731 0.0335 0.7969 0.6652
BALB/cByJ both 0.5756 0.0345 0.6434 0.5079
BALB/cJ both 0.6176 0.0327 0.6819 0.5534
BTBR T+ Itpr3tf/J both 0.5215 0.0308 0.5821 0.4609
BUB/BnJ both 0.6581 0.0317 0.7203 0.5958
C3H/HeJ both 0.6423 0.0317 0.7046 0.5801
C57BL/10J both 0.3479 0.0317 0.4102 0.2857
C57BL/6J both 0.4875 0.0345 0.5552 0.4198
C57BLKS/J both 0.3517 0.0304 0.4114 0.2919
C57BR/cdJ both 0.4942 0.034 0.561 0.4274
C57L/J both 0.4583 0.0356 0.5283 0.3884
CBA/J both 0.5916 0.0327 0.6559 0.5274
CE/J both 0.5694 0.0325 0.6333 0.5056
DBA/1J both 0.5248 0.0317 0.587 0.4625
DBA/2J both 0.484 0.0308 0.5446 0.4234
FVB/NJ both 0.499 0.0308 0.5596 0.4384
I/LnJ both 0.6015 0.0335 0.6673 0.5356
KK/HlJ both 0.5163 0.0317 0.5786 0.4541
LG/J both 0.4265 0.0308 0.4871 0.3659
LP/J both 0.3423 0.0317 0.4046 0.2801
MRL/MpJ both 0.5572 0.0325 0.6211 0.4934
NOD/ShiLtJ both 0.5211 0.0325 0.585 0.4572
NON/ShiLtJ both 0.6386 0.0369 0.711 0.5662
NZW/LacJ both 0.3567 0.0327 0.421 0.2925
P/J both 0.5649 0.0357 0.635 0.4948
PL/J both 0.6199 0.0335 0.6858 0.5541
RIIIS/J both 0.6447 0.0363 0.7161 0.5733
SJL/J both 0.4316 0.0335 0.4974 0.3658
SM/J both 0.5434 0.0327 0.6076 0.4791
SWR/J both 0.3513 0.0317 0.4136 0.2891




  GWAS USING LINEAR MIXED MODELS