Project measure / variable:   Berndt1   airway_res_saline

ID, description, units MPD:34210   airway_res_saline   airway resistance (H2O pressure)   [cm/mL/s]  baseline  
methacholine study
Data set, strains Berndt1   inbred   37 strains     sex: both     age: 9-12wks
Procedure ventilator
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt1 - airway resistance (H2O pressure) baseline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested36 strains33 strains
Mean of the strain means0.405   cm/mL/s 0.439   cm/mL/s
Median of the strain means0.419   cm/mL/s 0.467   cm/mL/s
SD of the strain means± 0.0897 ± 0.0874
Coefficient of variation (CV)0.221 0.199
Min–max range of strain means0.256   –   0.636   cm/mL/s 0.275   –   0.611   cm/mL/s
Mean sample size per strain8.6   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1222 0.1222 15.209 0.0001
strain 31 3.6977 0.1193 14.847 < 0.0001
sex:strain 31 0.831 0.0268 3.3367 < 0.0001
Residuals 509 4.0893 0.008


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.256 0.0336   9 0.0112 0.131 0.21, 0.3 -1.67
129S1/SvImJ m 0.306 0.0632   8 0.0224 0.206 0.2, 0.4 -1.52
A/J f 0.424 0.0956   10 0.0302 0.225 0.34, 0.65 0.21
A/J m 0.506 0.119   9 0.0398 0.236 0.37, 0.72 0.76
AKR/J f 0.498 0.106   9 0.0353 0.213 0.3, 0.66 1.03
AKR/J m 0.611 0.141   8 0.0499 0.231 0.35, 0.78 1.97
BALB/cByJ f 0.411 0.0557   8 0.0197 0.135 0.34, 0.52 0.06
BALB/cByJ m 0.539 0.179   8 0.0633 0.332 0.31, 0.9 1.14
BALB/cJ f 0.449 0.0683   8 0.0242 0.152 0.38, 0.56 0.49
BALB/cJ m 0.507 0.0825   10 0.0261 0.163 0.36, 0.65 0.78
BPN/3J f 0.336 0.0778   8 0.0275 0.231 0.25, 0.48 -0.77
BTBR T+ Itpr3tf/J f 0.424 0.112   10 0.0353 0.264 0.26, 0.63 0.21
BTBR T+ Itpr3tf/J m 0.397 0.034   10 0.0108 0.0857 0.35, 0.46 -0.48
BUB/BnJ f 0.636 0.114   9 0.038 0.179 0.48, 0.84 2.57
BUB/BnJ m 0.499 0.0973   10 0.0308 0.195 0.38, 0.68 0.68
C3H/HeJ f 0.551 0.145   10 0.0458 0.263 0.38, 0.76 1.62
C3H/HeJ m 0.512 0.086   9 0.0287 0.168 0.41, 0.66 0.83
C57BL/10J f 0.272 0.0393   9 0.0131 0.144 0.22, 0.36 -1.49
C57BL/10J m 0.337 0.0392   10 0.0124 0.116 0.27, 0.38 -1.17
C57BL/6J f 0.321 0.0799   8 0.0282 0.249 0.23, 0.44 -0.94
C57BL/6J m 0.495 0.121   8 0.0427 0.244 0.31, 0.64 0.64
C57BLKS/J f 0.26 0.0482   9 0.0161 0.185 0.19, 0.35 -1.62
C57BLKS/J m 0.35 0.0685   12 0.0198 0.196 0.25, 0.44 -1.02
C57BR/cdJ f 0.356 0.094   7 0.0355 0.264 0.28, 0.53 -0.55
C57BR/cdJ m 0.379 0.0667   10 0.0211 0.176 0.31, 0.5 -0.69
C57L/J f 0.427 0.154   6 0.0628 0.361 0.24, 0.57 0.24
C57L/J m 0.341 0.0694   10 0.0219 0.203 0.2, 0.48 -1.12
CBA/J f 0.482 0.0945   8 0.0334 0.196 0.37, 0.65 0.86
CBA/J m 0.465 0.0422   10 0.0134 0.0908 0.41, 0.53 0.3
CE/J f 0.417 0.0442   9 0.0147 0.106 0.33, 0.47 0.13
CE/J m 0.499 0.0615   9 0.0205 0.123 0.4, 0.61 0.68
DBA/1J f 0.452 0.0839   9 0.028 0.186 0.29, 0.57 0.52
DBA/1J m 0.433 0.105   10 0.0332 0.242 0.3, 0.62 -0.07
DBA/2J f 0.365 0.0517   10 0.0163 0.142 0.31, 0.45 -0.45
DBA/2J m 0.483 0.0693   10 0.0219 0.143 0.39, 0.57 0.5
FVB/NJ f 0.451 0.103   10 0.0325 0.228 0.27, 0.67 0.51
FVB/NJ m 0.375 0.168   10 0.0533 0.449 0.17, 0.65 -0.73
I/LnJ f 0.488 0.0939   9 0.0313 0.193 0.32, 0.59 0.92
I/LnJ m 0.501 0.0412   8 0.0146 0.0822 0.42, 0.54 0.71
KK/HlJ f 0.399 0.0688   9 0.0229 0.173 0.33, 0.53 -0.07
KK/HlJ m 0.367 0.0403   10 0.0127 0.11 0.31, 0.43 -0.83
LG/J f 0.33 0.0616   10 0.0195 0.187 0.23, 0.43 -0.84
LG/J m 0.332 0.0612   10 0.0194 0.184 0.26, 0.46 -1.23
LP/J f 0.267 0.0332   9 0.0111 0.124 0.21, 0.31 -1.54
LP/J m 0.317 0.0258   10 0.00817 0.0815 0.27, 0.35 -1.4
MA/MyJ f 0.422 0.0259   9 0.00862 0.0613 0.38, 0.45 0.19
MRL/MpJ f 0.456 0.0892   9 0.0297 0.196 0.34, 0.58 0.57
MRL/MpJ m 0.492 0.115   9 0.0384 0.234 0.33, 0.73 0.6
NOD/ShiLtJ f 0.352 0.067   9 0.0223 0.19 0.22, 0.44 -0.59
NOD/ShiLtJ m 0.494 0.0828   9 0.0276 0.167 0.38, 0.6 0.63
NON/ShiLtJ f 0.57 0.154   7 0.0581 0.27 0.43, 0.87 1.84
NON/ShiLtJ m 0.467 0.086   7 0.0325 0.184 0.36, 0.6 0.32
NZB/BlNJ m 0.364 0.106   10 0.0334 0.29 0.21, 0.61 -0.86
NZO/HlLtJ f 0.443 0.109   9 0.0362 0.245 0.33, 0.69 0.42
NZW/LacJ f 0.309 0.071   8 0.0251 0.23 0.23, 0.46 -1.07
NZW/LacJ m 0.275 0.0523   10 0.0165 0.19 0.2, 0.38 -1.88
P/J f 0.45 0.115   7 0.0435 0.256 0.32, 0.62 0.5
P/J m 0.517 0.141   8 0.0499 0.273 0.36, 0.73 0.89
PL/J f 0.411 0.111   9 0.0371 0.27 0.26, 0.53 0.06
PL/J m 0.603 0.116   8 0.041 0.193 0.49, 0.84 1.87
PWD/PhJ f 0.335 0.086   6 0.0351 0.257 0.23, 0.43 -0.78
RIIIS/J f 0.475 0.137   6 0.056 0.289 0.32, 0.68 0.78
RIIIS/J m 0.474 0.105   9 0.0352 0.222 0.28, 0.67 0.4
SJL/J f 0.36 0.0434   8 0.0154 0.121 0.29, 0.44 -0.51
SJL/J m 0.4 0.0532   9 0.0177 0.133 0.32, 0.47 -0.45
SM/J f 0.458 0.0704   10 0.0223 0.154 0.38, 0.55 0.59
SM/J m 0.505 0.0739   8 0.0261 0.146 0.39, 0.61 0.75
SWR/J f 0.279 0.044   9 0.0147 0.158 0.21, 0.35 -1.41
SWR/J m 0.352 0.0928   10 0.0294 0.264 0.27, 0.59 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2556 0.0299 0.3143 0.1969
129S1/SvImJ m 0.3062 0.0317 0.3685 0.244
A/J f 0.424 0.0283 0.4797 0.3683
A/J m 0.5056 0.0299 0.5643 0.4469
AKR/J f 0.4978 0.0299 0.5565 0.4391
AKR/J m 0.6113 0.0317 0.6735 0.549
BALB/cByJ f 0.4112 0.0317 0.4735 0.349
BALB/cByJ m 0.5387 0.0317 0.601 0.4765
BALB/cJ f 0.4488 0.0317 0.511 0.3865
BALB/cJ m 0.507 0.0283 0.5627 0.4513
BTBR T+ Itpr3tf/J f 0.424 0.0283 0.4797 0.3683
BTBR T+ Itpr3tf/J m 0.397 0.0283 0.4527 0.3413
BUB/BnJ f 0.6356 0.0299 0.6943 0.5769
BUB/BnJ m 0.499 0.0283 0.5547 0.4433
C3H/HeJ f 0.551 0.0283 0.6067 0.4953
C3H/HeJ m 0.5122 0.0299 0.5709 0.4535
C57BL/10J f 0.2722 0.0299 0.3309 0.2135
C57BL/10J m 0.337 0.0283 0.3927 0.2813
C57BL/6J f 0.3213 0.0317 0.3835 0.259
C57BL/6J m 0.495 0.0317 0.5573 0.4327
C57BLKS/J f 0.26 0.0299 0.3187 0.2013
C57BLKS/J m 0.35 0.0259 0.4008 0.2992
C57BR/cdJ f 0.3557 0.0339 0.4223 0.2892
C57BR/cdJ m 0.379 0.0283 0.4347 0.3233
C57L/J f 0.4267 0.0366 0.4986 0.3548
C57L/J m 0.341 0.0283 0.3967 0.2853
CBA/J f 0.4825 0.0317 0.5448 0.4202
CBA/J m 0.465 0.0283 0.5207 0.4093
CE/J f 0.4167 0.0299 0.4754 0.358
CE/J m 0.4989 0.0299 0.5576 0.4402
DBA/1J f 0.4522 0.0299 0.5109 0.3935
DBA/1J m 0.433 0.0283 0.4887 0.3773
DBA/2J f 0.365 0.0283 0.4207 0.3093
DBA/2J m 0.483 0.0283 0.5387 0.4273
FVB/NJ f 0.451 0.0283 0.5067 0.3953
FVB/NJ m 0.375 0.0283 0.4307 0.3193
I/LnJ f 0.4878 0.0299 0.5465 0.4291
I/LnJ m 0.5013 0.0317 0.5635 0.439
KK/HlJ f 0.3989 0.0299 0.4576 0.3402
KK/HlJ m 0.367 0.0283 0.4227 0.3113
LG/J f 0.33 0.0283 0.3857 0.2743
LG/J m 0.332 0.0283 0.3877 0.2763
LP/J f 0.2667 0.0299 0.3254 0.208
LP/J m 0.317 0.0283 0.3727 0.2613
MRL/MpJ f 0.4556 0.0299 0.5143 0.3969
MRL/MpJ m 0.4922 0.0299 0.5509 0.4335
NOD/ShiLtJ f 0.3522 0.0299 0.4109 0.2935
NOD/ShiLtJ m 0.4944 0.0299 0.5531 0.4357
NON/ShiLtJ f 0.57 0.0339 0.6366 0.5034
NON/ShiLtJ m 0.4671 0.0339 0.5337 0.4006
NZW/LacJ f 0.3088 0.0317 0.371 0.2465
NZW/LacJ m 0.275 0.0283 0.3307 0.2193
P/J f 0.45 0.0339 0.5166 0.3834
P/J m 0.5175 0.0317 0.5798 0.4552
PL/J f 0.4111 0.0299 0.4698 0.3524
PL/J m 0.6025 0.0317 0.6648 0.5402
RIIIS/J f 0.475 0.0366 0.5469 0.4031
RIIIS/J m 0.4744 0.0299 0.5331 0.4157
SJL/J f 0.36 0.0317 0.4223 0.2977
SJL/J m 0.4 0.0299 0.4587 0.3413
SM/J f 0.458 0.0283 0.5137 0.4023
SM/J m 0.505 0.0317 0.5673 0.4427
SWR/J f 0.2789 0.0299 0.3376 0.2202
SWR/J m 0.352 0.0283 0.4077 0.2963


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2809 0.0218 0.3237 0.2381
A/J both 0.4648 0.0206 0.5052 0.4243
AKR/J both 0.5545 0.0218 0.5973 0.5117
BALB/cByJ both 0.475 0.0224 0.519 0.431
BALB/cJ both 0.4779 0.0213 0.5196 0.4361
BTBR T+ Itpr3tf/J both 0.4105 0.02 0.4499 0.3711
BUB/BnJ both 0.5673 0.0206 0.6077 0.5268
C3H/HeJ both 0.5316 0.0206 0.5721 0.4912
C57BL/10J both 0.3046 0.0206 0.3451 0.2642
C57BL/6J both 0.4081 0.0224 0.4521 0.3641
C57BLKS/J both 0.305 0.0198 0.3438 0.2662
C57BR/cdJ both 0.3674 0.0221 0.4107 0.324
C57L/J both 0.3838 0.0231 0.4293 0.3384
CBA/J both 0.4738 0.0213 0.5155 0.432
CE/J both 0.4578 0.0211 0.4993 0.4163
DBA/1J both 0.4426 0.0206 0.4831 0.4022
DBA/2J both 0.424 0.02 0.4634 0.3846
FVB/NJ both 0.413 0.02 0.4524 0.3736
I/LnJ both 0.4945 0.0218 0.5373 0.4517
KK/HlJ both 0.3829 0.0206 0.4234 0.3425
LG/J both 0.331 0.02 0.3704 0.2916
LP/J both 0.2918 0.0206 0.3323 0.2514
MRL/MpJ both 0.4739 0.0211 0.5154 0.4324
NOD/ShiLtJ both 0.4233 0.0211 0.4648 0.3818
NON/ShiLtJ both 0.5186 0.024 0.5656 0.4715
NZW/LacJ both 0.2919 0.0213 0.3336 0.2501
P/J both 0.4838 0.0232 0.5293 0.4382
PL/J both 0.5068 0.0218 0.5496 0.464
RIIIS/J both 0.4747 0.0236 0.5211 0.4283
SJL/J both 0.38 0.0218 0.4228 0.3372
SM/J both 0.4815 0.0213 0.5233 0.4397
SWR/J both 0.3154 0.0206 0.3559 0.275




  GWAS USING LINEAR MIXED MODELS