Project measure / variable:   Shockley1   GLU_fat

ID, description, units MPD:33435   GLU_fat   glucose (serum GLU, 5h fast)   [mg/dL]  high-fat diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Shockley1 - glucose (serum GLU, 5h fast) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means113   mg/dL 135   mg/dL
Median of the strain means110   mg/dL 137   mg/dL
SD of the strain means± 25.8 ± 30.5
Coefficient of variation (CV)0.229 0.227
Min–max range of strain means73.5   –   140   mg/dL 76.0   –   178   mg/dL
Mean sample size per strain4.6   mice 4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6794.9776 6794.9776 14.0039 0.0004
strain 9 53210.3397 5912.26 12.1847 < 0.0001
sex:strain 9 10257.1215 1139.6802 2.3488 0.0223
Residuals 70 33965.35 485.2193


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 114.0 15.6   4 7.8 0.138 93.0, 131.0 0.04
129S1/SvImJ m 134.0 18.6   5 8.31 0.139 113.0, 151.0 -0.02
A/J f 79.8 17.9   4 8.94 0.224 54.0, 95.0 -1.28
A/J m 97.4 20.8   5 9.3 0.213 62.0, 117.0 -1.22
BALB/cJ f 93.4 15.7   5 7.03 0.168 74.0, 114.0 -0.75
BALB/cJ m 76.0 10.1   5 4.51 0.133 60.0, 85.0 -1.92
C3H/HeJ f 140.0 24.2   5 10.8 0.172 106.0, 169.0 1.05
C3H/HeJ m 160.0 12.0   2   8.5 0.0754 151.0, 168.0 0.83
C57BL/6J f 140.0 28.6   4 14.3 0.204 118.0, 181.0 1.05
C57BL/6J m 140.0 21.3   5 9.53 0.152 120.0, 166.0 0.18
DBA/2J f 139.0 14.8   5 6.62 0.107 122.0, 158.0 1.01
DBA/2J m 178.0 27.4   5 12.3 0.154 136.0, 204.0 1.42
I/LnJ f 73.5 12.0   2   8.5 0.164 65.0, 82.0 -1.53
I/LnJ m 151.0 31.9   5 14.3 0.211 109.0, 184.0 0.54
MRL/MpJ-Faslpr/J f 139.0 10.3   5 4.6 0.0739 124.0, 149.0 1.01
MRL/MpJ-Faslpr/J m 158.0 13.3   5 5.95 0.0841 140.0, 174.0 0.77
NZB/BlNJ f 106.0 14.0   5 6.24 0.132 86.0, 125.0 -0.27
NZB/BlNJ m 130.0 25.1   4 12.5 0.193 114.0, 167.0 -0.15
SM/J f 104.0 24.2   5 10.8 0.232 77.0, 135.0 -0.34
SM/J m 121.0 41.2   5 18.4 0.34 66.0, 172.0 -0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 113.5 11.0138 135.4664 91.5336
129S1/SvImJ m 134.0 9.8511 153.6474 114.3526
A/J f 79.75 11.0138 101.7164 57.7836
A/J m 97.4 9.8511 117.0474 77.7526
BALB/cJ f 93.4 9.8511 113.0474 73.7526
BALB/cJ m 76.0 9.8511 95.6474 56.3526
C3H/HeJ f 140.4 9.8511 160.0474 120.7526
C3H/HeJ m 159.5 15.5759 190.5652 128.4348
C57BL/6J f 140.5 11.0138 162.4664 118.5336
C57BL/6J m 140.0 9.8511 159.6474 120.3526
DBA/2J f 138.8 9.8511 158.4474 119.1526
DBA/2J m 178.4 9.8511 198.0474 158.7526
I/LnJ f 73.5 15.5759 104.5652 42.4348
I/LnJ m 151.4 9.8511 171.0474 131.7526
MRL/MpJ-Faslpr/J f 139.2 9.8511 158.8474 119.5526
MRL/MpJ-Faslpr/J m 158.2 9.8511 177.8474 138.5526
NZB/BlNJ f 105.6 9.8511 125.2474 85.9526
NZB/BlNJ m 130.0 11.0138 151.9664 108.0336
SM/J f 104.4 9.8511 124.0474 84.7526
SM/J m 121.2 9.8511 140.8474 101.5526


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 123.75 7.3883 138.4855 109.0145
A/J both 88.575 7.3883 103.3105 73.8395
BALB/cJ both 84.7 6.9658 98.5928 70.8072
C3H/HeJ both 149.95 9.2148 168.3284 131.5716
C57BL/6J both 140.25 7.3883 154.9855 125.5145
DBA/2J both 158.6 6.9658 172.4928 144.7072
I/LnJ both 112.45 9.2148 130.8284 94.0716
MRL/MpJ-Faslpr/J both 148.7 6.9658 162.5928 134.8072
NZB/BlNJ both 117.8 7.3883 132.5355 103.0645
SM/J both 112.8 6.9658 126.6928 98.9072




  GWAS USING LINEAR MIXED MODELS