Project measure / variable:   Shockley1   GLDH_fat

ID, description, units MPD:33434   GLDH_fat   glutamate dehydrogenase (GLDH)   [IU/L]  high-fat diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Shockley1 - glutamate dehydrogenase (GLDH) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means102   IU/L 180   IU/L
Median of the strain means74.3   IU/L 91.2   IU/L
SD of the strain means± 77.9 ± 200
Coefficient of variation (CV)0.765 1.11
Min–max range of strain means36.6   –   292   IU/L 39.7   –   667   IU/L
Mean sample size per strain4.8   mice 4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 65579.7583 65579.7583 18.8706 < 0.0001
strain 9 735032.3353 81670.2595 23.5006 < 0.0001
sex:strain 9 528208.4081 58689.8231 16.888 < 0.0001
Residuals 69 239791.4402 3475.2383


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 61.2 14.7   2   10.4 0.24 50.8, 71.6 -0.52
129S1/SvImJ m 48.8 37.1   5 16.6 0.761 25.7, 114.0 -0.66
A/J f 292.0 85.7   4 42.8 0.293 184.0, 384.0 2.44
A/J m 271.0 69.6   5 31.1 0.256 153.0, 325.0 0.45
BALB/cJ f 87.5 9.61   5 4.3 0.11 76.5, 103.0 -0.18
BALB/cJ m 354.0 144.0   5 64.2 0.405 229.0, 594.0 0.87
C3H/HeJ f 124.0 40.6   5 18.2 0.327 87.1, 178.0 0.28
C3H/HeJ m 667.0 76.4   2   54.0 0.114 613.0, 721.0 2.43
C57BL/6J f 102.0 55.0   5 24.6 0.541 33.0, 156.0 0.0
C57BL/6J m 76.9 40.0   5 17.9 0.52 40.9, 142.0 -0.52
DBA/2J f 55.5 18.6   5 8.31 0.335 33.9, 82.3 -0.6
DBA/2J m 77.4 17.2   3 9.95 0.222 60.8, 95.2 -0.51
I/LnJ f 164.0 130.0   4 65.0 0.792 56.8, 353.0 0.8
I/LnJ m 105.0 52.9   5 23.7 0.502 42.8, 187.0 -0.38
MRL/MpJ-Faslpr/J f 36.6 14.8   5 6.63 0.405 16.5, 56.0 -0.84
MRL/MpJ-Faslpr/J m 53.0 29.9   5 13.4 0.564 22.4, 103.0 -0.63
NZB/BlNJ f 53.8 10.8   5 4.83 0.201 45.6, 72.7 -0.62
NZB/BlNJ m 108.0 45.1   4 22.5 0.417 52.1, 156.0 -0.36
SM/J f 42.2 30.6   5 13.7 0.726 16.4, 93.9 -0.77
SM/J m 39.7 7.87   5 3.52 0.198 32.3, 51.9 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 61.2 41.6848 144.3588 0.0
129S1/SvImJ m 48.8 26.3638 101.3943 0.0
A/J f 292.25 29.4756 351.0522 233.4478
A/J m 271.4 26.3638 323.9943 218.8057
BALB/cJ f 87.5 26.3638 140.0943 34.9057
BALB/cJ m 354.2 26.3638 406.7943 301.6057
C3H/HeJ f 124.1 26.3638 176.6943 71.5057
C3H/HeJ m 667.0 41.6848 750.1588 583.8412
C57BL/6J f 101.7 26.3638 154.2943 49.1057
C57BL/6J m 76.86 26.3638 129.4543 24.2657
DBA/2J f 55.5 26.3638 108.0943 2.9057
DBA/2J m 77.4333 34.0355 145.3322 9.5344
I/LnJ f 164.2 29.4756 223.0022 105.3978
I/LnJ m 105.36 26.3638 157.9543 52.7657
MRL/MpJ-Faslpr/J f 36.62 26.3638 89.2143 0.0
MRL/MpJ-Faslpr/J m 52.96 26.3638 105.5543 0.3657
NZB/BlNJ f 53.84 26.3638 106.4343 1.2457
NZB/BlNJ m 108.175 29.4756 166.9772 49.3728
SM/J f 42.2 26.3638 94.7943 0.0
SM/J m 39.7 26.3638 92.2943 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 55.0 24.661 104.1974 5.8026
A/J both 281.825 19.7728 321.2707 242.3793
BALB/cJ both 220.85 18.642 258.0398 183.6602
C3H/HeJ both 395.55 24.661 444.7474 346.3526
C57BL/6J both 89.28 18.642 126.4698 52.0902
DBA/2J both 66.4667 21.5259 109.4097 23.5236
I/LnJ both 134.78 19.7728 174.2257 95.3343
MRL/MpJ-Faslpr/J both 44.79 18.642 81.9798 7.6002
NZB/BlNJ both 81.0075 19.7728 120.4532 41.5618
SM/J both 40.95 18.642 78.1398 3.7602




GWAS analysis not available: At least 12 strains are required