Project measure / variable:   Shockley1   BUN_fat

ID, description, units MPD:33432   BUN_fat   blood urea nitrogen (BUN)   [mg/dL]  high-fat diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Shockley1 - blood urea nitrogen (BUN) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means19.6   mg/dL 22.5   mg/dL
Median of the strain means19.0   mg/dL 21.8   mg/dL
SD of the strain means± 4.03 ± 3.77
Coefficient of variation (CV)0.206 0.168
Min–max range of strain means14.2   –   26.0   mg/dL 18.0   –   30.4   mg/dL
Mean sample size per strain3.3   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 166.6006 166.6006 3.1359 0.0853
strain 5 361.3281 72.2656 1.3602 0.2628
sex:strain 5 167.8387 33.5677 0.6318 0.6767
Residuals 35 1859.4667 53.1276


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 19.0 2.16   4 1.08 0.114 17.0, 22.0 -0.14
129S1/SvImJ m 25.6 11.0   5 4.92 0.429 17.0, 43.0 0.82
A/J f 22.0 7.62   4 3.81 0.346 16.0, 33.0 0.6
A/J m 30.4 16.3   5 7.3 0.537 17.0, 51.0 2.09
BALB/cJ f 18.6 2.61   5 1.17 0.14 16.0, 22.0 -0.24
BALB/cJ m 20.0 2.55   5 1.14 0.127 17.0, 23.0 -0.66
C3H/HeJ f 16.4 2.51   5 1.12 0.153 13.0, 20.0 -0.79
C3H/HeJ m 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.13
C57BL/6J f 26.0 0.0   1   0.0 0.0 26.0, 26.0 1.59
DBA/2J f 16.0 0.0   2   0.0 0.0 16.0, 16.0 -0.89
DBA/2J m 20.0 3.0   5 1.34 0.15 17.0, 25.0 -0.66
I/LnJ m 21.8 1.26   4 0.629 0.0579 20.0, 23.0 -0.19
MRL/MpJ-Faslpr/J f 19.0 1.41   2   1.0 0.0744 18.0, 20.0 -0.14
MRL/MpJ-Faslpr/J m 24.4 0.894   5 0.4 0.0367 23.0, 25.0 0.5
NZB/BlNJ f 14.2 0.957   4 0.479 0.0672 13.0, 15.0 -1.33
NZB/BlNJ m 18.0 0.0   1   0.0 0.0 18.0, 18.0 -1.19
SM/J f 25.0 4.24   2   3.0 0.17 22.0, 28.0 1.35
SM/J m 20.3 2.08   3 1.2 0.102 18.0, 22.0 -0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 19.0 3.6444 26.3986 11.6014
129S1/SvImJ m 25.6 3.2597 32.2175 18.9825
A/J f 22.0 3.6444 29.3986 14.6014
A/J m 30.4 3.2597 37.0175 23.7825
BALB/cJ f 18.6 3.2597 25.2175 11.9825
BALB/cJ m 20.0 3.2597 26.6175 13.3825
DBA/2J f 16.0 5.154 26.4632 5.5368
DBA/2J m 20.0 3.2597 26.6175 13.3825
MRL/MpJ-Faslpr/J f 19.0 5.154 29.4632 8.5368
MRL/MpJ-Faslpr/J m 24.4 3.2597 31.0175 17.7825
SM/J f 25.0 5.154 35.4632 14.5368
SM/J m 20.3333 4.2082 28.8765 11.7902


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 22.3 2.4448 27.2631 17.3369
A/J both 26.2 2.4448 31.1631 21.2369
BALB/cJ both 19.3 2.3049 23.9793 14.6207
DBA/2J both 18.0 3.0492 24.1901 11.8099
MRL/MpJ-Faslpr/J both 21.7 3.0492 27.8901 15.5099
SM/J both 22.6667 3.3269 29.4206 15.9127




  GWAS USING LINEAR MIXED MODELS