Project measure / variable:   Shockley1   GLU

ID, description, units MPD:33405   GLU   glucose (serum GLU, 5h fast)   [mg/dL]  control diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Shockley1 - glucose (serum GLU, 5h fast) control diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means120   mg/dL 135   mg/dL
Median of the strain means127   mg/dL 140   mg/dL
SD of the strain means± 18.0 ± 19.3
Coefficient of variation (CV)0.150 0.143
Min–max range of strain means86.4   –   142   mg/dL 98.6   –   160   mg/dL
Mean sample size per strain4.9   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5382.3827 5382.3827 13.859 0.0004
strain 9 25138.6025 2793.1781 7.1921 < 0.0001
sex:strain 9 6006.4475 667.3831 1.7184 0.0988
Residuals 78 30292.7 388.3679


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 127.0 14.5   5 6.48 0.114 109.0, 144.0 0.38
129S1/SvImJ m 113.0 26.5   5 11.9 0.234 83.0, 155.0 -1.12
A/J f 137.0 18.4   5 8.22 0.134 117.0, 160.0 0.93
A/J m 141.0 5.22   5 2.33 0.0369 134.0, 148.0 0.33
BALB/cJ f 105.0 9.71   5 4.34 0.0926 97.0, 120.0 -0.85
BALB/cJ m 98.6 31.6   5 14.2 0.321 74.0, 153.0 -1.86
C3H/HeJ f 142.0 12.3   5 5.5 0.0867 134.0, 163.0 1.21
C3H/HeJ m 159.0 11.6   5 5.2 0.0732 144.0, 176.0 1.27
C57BL/6J f 130.0 18.6   5 8.32 0.143 107.0, 159.0 0.54
C57BL/6J m 160.0 29.4   5 13.2 0.184 131.0, 193.0 1.32
DBA/2J f 120.0 7.99   5 3.57 0.0668 107.0, 129.0 -0.01
DBA/2J m 141.0 3.44   5 1.54 0.0243 138.0, 146.0 0.33
I/LnJ f 127.0 29.5   4 14.8 0.233 103.0, 168.0 0.38
I/LnJ m 142.0 20.4   5 9.14 0.144 115.0, 172.0 0.39
MRL/MpJ-Faslpr/J f 130.0 30.1   4 15.1 0.231 97.0, 166.0 0.54
MRL/MpJ-Faslpr/J m 140.0 12.4   5 5.56 0.0885 124.0, 156.0 0.28
NZB/BlNJ f 86.4 14.3   5 6.4 0.166 63.0, 99.0 -1.88
NZB/BlNJ m 123.0 30.8   5 13.8 0.25 93.0, 157.0 -0.6
SM/J f 98.0 17.0   5 7.6 0.173 81.0, 126.0 -1.24
SM/J m 128.0 16.6   5 7.43 0.13 107.0, 144.0 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 127.2 8.8133 144.7459 109.6541
129S1/SvImJ m 113.2 8.8133 130.7459 95.6541
A/J f 137.2 8.8133 154.7459 119.6541
A/J m 141.2 8.8133 158.7459 123.6541
BALB/cJ f 104.8 8.8133 122.3459 87.2541
BALB/cJ m 98.6 8.8133 116.1459 81.0541
C3H/HeJ f 141.8 8.8133 159.3459 124.2541
C3H/HeJ m 158.8 8.8133 176.3459 141.2541
C57BL/6J f 130.2 8.8133 147.7459 112.6541
C57BL/6J m 160.0 8.8133 177.5459 142.4541
DBA/2J f 119.6 8.8133 137.1459 102.0541
DBA/2J m 141.4 8.8133 158.9459 123.8541
I/LnJ f 126.75 9.8535 146.3669 107.1331
I/LnJ m 142.2 8.8133 159.7459 124.6541
MRL/MpJ-Faslpr/J f 130.25 9.8535 149.8669 110.6331
MRL/MpJ-Faslpr/J m 140.4 8.8133 157.9459 122.8541
NZB/BlNJ f 86.4 8.8133 103.9459 68.8541
NZB/BlNJ m 123.4 8.8133 140.9459 105.8541
SM/J f 98.0 8.8133 115.5459 80.4541
SM/J m 127.8 8.8133 145.3459 110.2541


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 120.2 6.2319 132.6068 107.7932
A/J both 139.2 6.2319 151.6068 126.7932
BALB/cJ both 101.7 6.2319 114.1068 89.2932
C3H/HeJ both 150.3 6.2319 162.7068 137.8932
C57BL/6J both 145.1 6.2319 157.5068 132.6932
DBA/2J both 130.5 6.2319 142.9068 118.0932
I/LnJ both 134.475 6.6099 147.6344 121.3156
MRL/MpJ-Faslpr/J both 135.325 6.6099 148.4844 122.1656
NZB/BlNJ both 104.9 6.2319 117.3068 92.4932
SM/J both 112.9 6.2319 125.3068 100.4932




  GWAS USING LINEAR MIXED MODELS