Project measure / variable:   Maurer1   heart_adjwt_at

ID, description, units MPD:33275   heart_adjwt_at   heart weight normalized to body weight   [mg/g]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Maurer1 - heart weight normalized to body weight atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means4.26   mg/g
Median of the strain means4.20   mg/g
SD of the strain means± 0.418
Coefficient of variation (CV)0.0981
Min–max range of strain means3.58   –   5.46   mg/g
Mean sample size per strain10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 39.7698 1.8077 27.7595 < 0.0001
Residuals 217 14.1312 0.0651


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 4.66 0.221   13 0.0612 0.0474 4.17, 5.0 0.95
A/J m 3.84 0.287   10 0.0907 0.0747 3.63, 4.62 -1.01
AKR/J m 4.27 0.233   9 0.0776 0.0545 4.06, 4.67 0.01
BALB/cByJ m 4.5 0.201   16 0.0502 0.0446 4.21, 4.89 0.56
BALB/cJ m 4.11 0.486   10 0.154 0.118 3.61, 5.42 -0.37
BTBR T+ Itpr3tf/J m 4.3 0.192   9 0.0639 0.0446 4.05, 4.59 0.09
C3H/HeJ m 3.58 0.319   10 0.101 0.0893 3.19, 4.36 -1.64
C3H/HeOuJ m 3.8 0.19   10 0.0602 0.0501 3.55, 4.13 -1.11
C57BL/6J m 4.2 0.0915   9 0.0305 0.0218 4.01, 4.36 -0.15
C57BLKS/J m 4.33 0.131   9 0.0438 0.0303 4.1, 4.51 0.16
C58/J m 3.87 0.224   12 0.0646 0.0578 3.61, 4.23 -0.94
CBA/J m 4.01 0.107   9 0.0358 0.0268 3.87, 4.18 -0.61
DBA/2J m 4.87 0.313   10 0.0991 0.0644 4.4, 5.39 1.45
FVB/NJ m 4.05 0.151   14 0.0405 0.0374 3.72, 4.21 -0.51
I/LnJ m 4.74 0.3   10 0.095 0.0634 4.21, 5.21 1.14
KK/HlJ m 3.98 0.166   9 0.0552 0.0417 3.77, 4.22 -0.68
LP/J m 4.2 0.208   10 0.0656 0.0494 3.9, 4.52 -0.15
NOD/ShiLtJ m 3.92 0.219   10 0.0692 0.0558 3.61, 4.23 -0.82
NZB/BlNJ m 4.64 0.141   9 0.0472 0.0305 4.39, 4.84 0.9
PL/J m 5.46 0.544   10 0.172 0.0996 4.68, 6.54 2.86
SJL/J m 4.18 0.198   9 0.066 0.0474 3.97, 4.6 -0.2
SM/J m 4.51 0.301   12 0.0869 0.0668 4.12, 4.95 0.59
SWR/J m 4.06 0.0966   11 0.0291 0.0238 3.94, 4.23 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 4.6569 0.0708 4.7964 4.5174
A/J m 3.84 0.0807 3.9991 3.6809
AKR/J m 4.2722 0.0851 4.4399 4.1046
BALB/cByJ m 4.5044 0.0638 4.6301 4.3786
BALB/cJ m 4.108 0.0807 4.2671 3.9489
BTBR T+ Itpr3tf/J m 4.3011 0.0851 4.4688 4.1335
C3H/HeJ m 3.575 0.0807 3.7341 3.4159
C3H/HeOuJ m 3.799 0.0807 3.9581 3.6399
C57BL/6J m 4.1956 0.0851 4.3632 4.0279
C57BLKS/J m 4.33 0.0851 4.4977 4.1623
C58/J m 3.8708 0.0737 4.016 3.7256
CBA/J m 4.0089 0.0851 4.1765 3.8412
DBA/2J m 4.865 0.0807 5.0241 4.7059
FVB/NJ m 4.0493 0.0682 4.1837 3.9149
I/LnJ m 4.74 0.0807 4.8991 4.5809
KK/HlJ m 3.9756 0.0851 4.1432 3.8079
LP/J m 4.202 0.0807 4.3611 4.0429
NOD/ShiLtJ m 3.918 0.0807 4.0771 3.7589
NZB/BlNJ m 4.6411 0.0851 4.8088 4.4735
PL/J m 5.462 0.0807 5.6211 5.3029
SJL/J m 4.1789 0.0851 4.3465 4.0112
SM/J m 4.5058 0.0737 4.651 4.3606
SWR/J m 4.0609 0.0769 4.2126 3.9093




  GWAS USING LINEAR MIXED MODELS