Project measure / variable:   Maurer1   QT_ctrl

ID, description, units MPD:33245   QT_ctrl   interval QT   [ms]  control  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval QT control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means55.3   ms
Median of the strain means55.0   ms
SD of the strain means± 5.35
Coefficient of variation (CV)0.0967
Min–max range of strain means43.1   –   63.0   ms
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 5967.4101 271.2459 2.7748 0.0001
Residuals 202 19745.8425 97.7517


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 58.3 6.59   13 1.83 0.113 47.2, 71.5 0.56
A/J m 46.3 10.7   11 3.23 0.232 23.0, 59.9 -1.68
AKR/J m 58.8 6.56   8 2.32 0.112 50.9, 69.7 0.65
BALB/cByJ m 63.0 3.24   9 1.08 0.0514 58.3, 68.1 1.44
BALB/cJ m 53.0 5.25   10 1.66 0.0992 45.0, 63.6 -0.43
BTBR T+ Itpr3tf/J m 58.2 4.55   10 1.44 0.0781 51.9, 66.8 0.54
C3H/HeJ m 51.7 9.11   10 2.88 0.176 29.0, 60.1 -0.67
C3H/HeOuJ m 58.4 5.18   9 1.73 0.0888 49.6, 65.0 0.58
C57BL/6J m 53.2 2.92   9 0.974 0.0549 47.6, 57.6 -0.39
C57BLKS/J m 60.5 4.54   10 1.44 0.0751 53.1, 70.1 0.97
C58/J m 57.3 7.97   12 2.3 0.139 48.3, 72.7 0.37
CBA/J m 51.1 9.69   8 3.42 0.19 30.0, 62.2 -0.79
DBA/2J m 62.1 15.0   6 6.12 0.241 40.4, 75.8 1.27
FVB/NJ m 53.9 4.59   12 1.33 0.0851 47.5, 64.0 -0.26
I/LnJ m 62.9 34.4   10 10.9 0.546 17.9, 128.0 1.42
KK/HlJ m 56.8 2.79   10 0.883 0.0491 51.9, 61.9 0.28
LP/J m 50.8 3.7   8 1.31 0.0729 44.4, 57.0 -0.84
NOD/ShiLtJ m 53.3 4.65   9 1.55 0.0871 44.8, 60.4 -0.37
NZB/BlNJ m 47.9 2.44   8 0.864 0.0511 42.6, 50.8 -1.38
PL/J m 55.0 8.35   10 2.64 0.152 37.9, 66.4 -0.06
SJL/J m 43.1 2.62   9 0.872 0.0607 39.0, 46.2 -2.28
SM/J m 61.8 8.72   14 2.33 0.141 51.3, 81.2 1.21
SWR/J m 54.6 8.55   10 2.7 0.157 43.8, 66.8 -0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 58.3308 2.7421 63.7377 52.9239
A/J m 46.3091 2.981 52.187 40.4312
AKR/J m 58.775 3.4956 65.6675 51.8825
BALB/cByJ m 63.0111 3.2956 69.5094 56.5128
BALB/cJ m 52.97 3.1265 59.1348 46.8052
BTBR T+ Itpr3tf/J m 58.2 3.1265 64.3648 52.0352
C3H/HeJ m 51.66 3.1265 57.8248 45.4952
C3H/HeOuJ m 58.3556 3.2956 64.8538 51.8573
C57BL/6J m 53.2333 3.2956 59.7316 46.735
C57BLKS/J m 60.47 3.1265 66.6348 54.3052
C58/J m 57.325 2.8541 62.9527 51.6973
CBA/J m 51.1 3.4956 57.9925 44.2075
DBA/2J m 62.15 4.0363 70.1087 54.1913
FVB/NJ m 53.9167 2.8541 59.5443 48.289
I/LnJ m 62.91 3.1265 69.0748 56.7452
KK/HlJ m 56.82 3.1265 62.9848 50.6552
LP/J m 50.775 3.4956 57.6675 43.8825
NOD/ShiLtJ m 53.3111 3.2956 59.8094 46.8128
NZB/BlNJ m 47.875 3.4956 54.7675 40.9825
PL/J m 54.95 3.1265 61.1148 48.7852
SJL/J m 43.0778 3.2956 49.5761 36.5795
SM/J m 61.75 2.6424 66.9602 56.5398
SWR/J m 54.6 3.1265 60.7648 48.4352




  GWAS USING LINEAR MIXED MODELS