Project measure / variable:   Maurer1   Q_amp_at

ID, description, units MPD:33218   Q_amp_at   amplitude of Q-wave   [mV]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   22 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - amplitude of Q-wave atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested22 strains
Mean of the strain means-0.0462   mV
Median of the strain means-0.0429   mV
SD of the strain means± 0.0355
Coefficient of variation (CV)-0.770
Min–max range of strain means-0.151   –   0.00286   mV
Mean sample size per strain8.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 0.2143 0.0107 7.6331 < 0.0001
Residuals 168 0.2359 0.0014


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m -0.0577 0.0311   13 0.00863 -0.54 -0.1, -0.01 -0.33
A/J m -0.0633 0.00577   3 0.00333 -0.0912 -0.07, -0.06 -0.48
AKR/J m 0.00286 0.0111   7 0.00421 3.89 -0.01, 0.02 1.38
BALB/cByJ m -0.015 0.0212   2   0.015 -1.41 -0.03, 0.0 0.88
BALB/cJ m -0.048 0.0346   10 0.0109 -0.72 -0.12, 0.01 -0.05
BTBR T+ Itpr3tf/J m -0.151 0.0379   9 0.0126 -0.251 -0.22, -0.11 -2.95
C3H/HeJ m -0.0329 0.0309   7 0.0117 -0.942 -0.09, -0.01 0.37
C57BL/6J m -0.0378 0.0315   9 0.0105 -0.835 -0.09, 0.0 0.24
C57BLKS/J m -0.0767 0.0748   9 0.0249 -0.976 -0.21, -0.01 -0.86
C58/J m -0.0717 0.031   12 0.00895 -0.432 -0.14, -0.03 -0.72
CBA/J m -0.003 0.0   1   0.0 0.0 -0.003, -0.003 1.22
DBA/2J m -0.0322 0.0307   5 0.0137 -0.953 -0.076, 0.0 0.39
FVB/NJ m -0.0557 0.0427   14 0.0114 -0.767 -0.16, -0.01 -0.27
I/LnJ m -0.0344 0.0101   9 0.00338 -0.294 -0.05, -0.02 0.33
KK/HlJ m -0.0578 0.0233   9 0.00778 -0.404 -0.08, -0.01 -0.33
LP/J m -0.069 0.0375   10 0.0119 -0.544 -0.12, -0.02 -0.64
NOD/ShiLtJ m -0.079 0.039   10 0.0123 -0.494 -0.14, -0.02 -0.92
NZB/BlNJ m -0.00778 0.0399   9 0.0133 -5.13 -0.1, 0.03 1.08
PL/J m -0.081 0.0689   10 0.0218 -0.85 -0.16, 0.01 -0.98
SJL/J m -0.0138 0.0111   9 0.0037 -0.806 -0.04, 0.0 0.91
SM/J m -0.025 0.0366   12 0.0106 -1.46 -0.09, 0.01 0.6
SWR/J m -0.00545 0.0121   11 0.00366 -2.22 -0.03, 0.02 1.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m -0.0577 0.0104 -0.0372 -0.0782
A/J m -0.0633 0.0216 -0.0206 -0.106
AKR/J m 0.0029 0.0142 0.0308 -0.0251
BALB/cByJ m -0.015 0.0265 0.0373 -0.0673
BALB/cJ m -0.048 0.0118 -0.0246 -0.0714
BTBR T+ Itpr3tf/J m -0.1511 0.0125 -0.1265 -0.1758
C3H/HeJ m -0.0329 0.0142 -0.0049 -0.0608
C57BL/6J m -0.0378 0.0125 -0.0131 -0.0624
C57BLKS/J m -0.0767 0.0125 -0.052 -0.1013
C58/J m -0.0717 0.0108 -0.0503 -0.093
DBA/2J m -0.0322 0.0168 0.0009 -0.0653
FVB/NJ m -0.0557 0.01 -0.0359 -0.0755
I/LnJ m -0.0344 0.0125 -0.0098 -0.0591
KK/HlJ m -0.0578 0.0125 -0.0331 -0.0824
LP/J m -0.069 0.0118 -0.0456 -0.0924
NOD/ShiLtJ m -0.079 0.0118 -0.0556 -0.1024
NZB/BlNJ m -0.0078 0.0125 0.0169 -0.0324
PL/J m -0.081 0.0118 -0.0576 -0.1044
SJL/J m -0.0138 0.0125 0.0109 -0.0384
SM/J m -0.025 0.0108 -0.0036 -0.0464
SWR/J m -0.0055 0.0113 0.0168 -0.0278




  GWAS USING LINEAR MIXED MODELS