Project measure / variable:   Maurer1   BP_at

ID, description, units MPD:33210   BP_at   systolic blood pressure   [mmHg]  atenolol 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure tail cuff
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  STRAIN COMPARISON PLOT
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Maurer1 - systolic blood pressure atenolol 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means99.3   mmHg
Median of the strain means101   mmHg
SD of the strain means± 10.3
Coefficient of variation (CV)0.103
Min–max range of strain means82.8   –   117   mmHg
Mean sample size per strain10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 22364.4853 1016.5675 10.7257 < 0.0001
Residuals 207 19619.1734 94.7786


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 111.0 7.93   13 2.2 0.0713 100.0, 123.0 1.14
A/J m 84.9 6.08   10 1.92 0.0716 77.4, 97.0 -1.4
AKR/J m 103.0 9.23   9 3.08 0.0898 87.2, 114.0 0.36
BALB/cByJ m 104.0 12.1   16 3.03 0.117 82.8, 124.0 0.46
BALB/cJ m 90.0 11.2   9 3.73 0.124 72.3, 110.0 -0.9
BTBR T+ Itpr3tf/J m 84.9 6.6   3 3.81 0.0778 79.7, 92.3 -1.4
C3H/HeJ m 94.5 14.6   9 4.87 0.155 77.7, 120.0 -0.47
C3H/HeOuJ m 109.0 4.77   10 1.51 0.0437 103.0, 118.0 0.95
C57BL/6J m 96.6 8.8   9 2.93 0.0911 84.7, 111.0 -0.26
C57BLKS/J m 100.0 10.3   9 3.44 0.103 85.1, 119.0 0.07
C58/J m 88.6 12.0   11 3.62 0.135 63.1, 100.0 -1.04
CBA/J m 107.0 11.8   9 3.92 0.11 88.5, 126.0 0.75
DBA/2J m 101.0 6.23   10 1.97 0.062 90.9, 110.0 0.17
FVB/NJ m 111.0 8.35   13 2.32 0.0753 93.3, 123.0 1.14
I/LnJ m 84.6 10.6   9 3.53 0.125 66.8, 101.0 -1.43
KK/HlJ m 93.9 7.93   10 2.51 0.0845 80.0, 104.0 -0.52
LP/J m 91.8 10.6   10 3.36 0.116 73.8, 105.0 -0.73
NOD/ShiLtJ m 114.0 7.91   10 2.5 0.0694 96.0, 125.0 1.43
NZB/BlNJ m 101.0 7.33   9 2.44 0.0724 96.0, 117.0 0.17
PL/J m 106.0 9.09   10 2.87 0.0856 87.1, 118.0 0.65
SJL/J m 82.8 9.91   9 3.3 0.12 66.0, 93.3 -1.6
SM/J m 107.0 10.0   12 2.89 0.0935 83.3, 121.0 0.75
SWR/J m 117.0 11.6   11 3.49 0.0989 91.0, 133.0 1.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 111.3077 2.7001 116.631 105.9844
A/J m 84.88 3.0786 90.9495 78.8105
AKR/J m 102.8444 3.2451 109.2422 96.4467
BALB/cByJ m 103.7562 2.4339 108.5546 98.9579
BALB/cJ m 89.9556 3.2451 96.3533 83.5578
BTBR T+ Itpr3tf/J m 84.8667 5.6208 95.9479 73.7854
C3H/HeJ m 94.5333 3.2451 100.9311 88.1356
C3H/HeOuJ m 109.1 3.0786 115.1695 103.0305
C57BL/6J m 96.5667 3.2451 102.9644 90.1689
C57BLKS/J m 100.0 3.2451 106.3978 93.6022
C58/J m 88.6273 2.9353 94.4143 82.8403
CBA/J m 106.9333 3.2451 113.3311 100.5356
DBA/2J m 100.55 3.0786 106.6195 94.4805
FVB/NJ m 110.8692 2.7001 116.1925 105.546
I/LnJ m 84.5556 3.2451 90.9533 78.1578
KK/HlJ m 93.9 3.0786 99.9695 87.8305
LP/J m 91.75 3.0786 97.8195 85.6805
NOD/ShiLtJ m 113.9 3.0786 119.9695 107.8305
NZB/BlNJ m 101.1444 3.2451 107.5422 94.7467
PL/J m 106.11 3.0786 112.1795 100.0405
SJL/J m 82.7556 3.2451 89.1533 76.3578
SM/J m 106.975 2.8104 112.5156 101.4344
SWR/J m 117.0 2.9353 122.787 111.213




  GWAS USING LINEAR MIXED MODELS