Project measure / variable:   Schonfeld1   pct_ITT120

ID, description, units MPD:32316   pct_ITT120   glucose levels as percent of baseline, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast)   [%]  at 120 min  
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
Procedure insulin tolerance
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  STRAIN COMPARISON PLOT
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Schonfeld1 - glucose levels as percent of baseline, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast) at 120 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means56.8   % 52.3   %
Median of the strain means53.3   % 55.1   %
SD of the strain means± 20.5 ± 16.1
Coefficient of variation (CV)0.360 0.308
Min–max range of strain means24.5   –   89.8   % 29.7   –   78.4   %
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 121.104 121.104 1.086 0.3008
strain 8 23873.7889 2984.2236 26.7617 < 0.0001
sex:strain 8 3142.416 392.802 3.5225 0.0017
Residuals 72 8028.804 111.5112


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 24.5 10.3   5 4.6 0.419 14.4, 38.2 -1.58
129X1/SvJ m 29.7 14.4   5 6.44 0.485 16.5, 53.3 -1.4
AKR/J f 76.4 6.6   5 2.95 0.0864 65.4, 81.9 0.96
BALB/cByJ f 69.4 3.44   5 1.54 0.0495 65.6, 74.3 0.62
BALB/cByJ m 78.4 14.6   5 6.52 0.186 63.1, 96.4 1.62
C3H/HeJ f 53.9 6.8   5 3.04 0.126 49.0, 65.3 -0.14
C3H/HeJ m 55.1 11.0   5 4.92 0.199 38.3, 66.2 0.18
C57BL/6ByJ f 89.8 13.9   5 6.22 0.155 77.6, 113.0 1.61
C57BL/6ByJ m 63.4 13.0   5 5.79 0.204 50.9, 83.0 0.69
C57BL/6J f 52.7 9.36   5 4.18 0.177 42.3, 65.2 -0.2
C57BL/6J m 52.0 9.31   5 4.16 0.179 43.1, 66.5 -0.02
DBA/1LacJ f 74.3 13.5   5 6.05 0.182 62.5, 96.3 0.86
DBA/1LacJ m 64.0 10.4   5 4.67 0.163 50.3, 75.0 0.73
NZB/BlNJ f 51.3 9.03   5 4.04 0.176 40.0, 61.1 -0.27
NZB/BlNJ m 42.1 11.1   5 4.96 0.264 26.2, 52.9 -0.63
PL/J f 39.3 2.89   5 1.29 0.0736 34.5, 42.1 -0.85
PL/J m 55.7 12.2   5 5.45 0.219 43.4, 75.0 0.21
SWR/J f 36.2 6.8   5 3.04 0.188 28.7, 45.0 -1.01
SWR/J m 30.1 8.23   5 3.68 0.274 22.7, 39.1 -1.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 24.52 4.7225 33.9342 15.1058
129X1/SvJ m 29.72 4.7225 39.1342 20.3058
BALB/cByJ f 69.36 4.7225 78.7742 59.9458
BALB/cByJ m 78.36 4.7225 87.7742 68.9458
C3H/HeJ f 53.88 4.7225 63.2942 44.4658
C3H/HeJ m 55.12 4.7225 64.5342 45.7058
C57BL/6ByJ f 89.76 4.7225 99.1742 80.3458
C57BL/6ByJ m 63.38 4.7225 72.7942 53.9658
C57BL/6J f 52.74 4.7225 62.1542 43.3258
C57BL/6J m 52.02 4.7225 61.4342 42.6058
DBA/1LacJ f 74.32 4.7225 83.7342 64.9058
DBA/1LacJ m 63.98 4.7225 73.3942 54.5658
NZB/BlNJ f 51.28 4.7225 60.6942 41.8658
NZB/BlNJ m 42.06 4.7225 51.4742 32.6458
PL/J f 39.28 4.7225 48.6942 29.8658
PL/J m 55.72 4.7225 65.1342 46.3058
SWR/J f 36.18 4.7225 45.5942 26.7658
SWR/J m 30.08 4.7225 39.4942 20.6658


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 27.12 3.3393 33.7768 20.4632
BALB/cByJ both 73.86 3.3393 80.5168 67.2032
C3H/HeJ both 54.5 3.3393 61.1568 47.8432
C57BL/6ByJ both 76.57 3.3393 83.2268 69.9132
C57BL/6J both 52.38 3.3393 59.0368 45.7232
DBA/1LacJ both 69.15 3.3393 75.8068 62.4932
NZB/BlNJ both 46.67 3.3393 53.3268 40.0132
PL/J both 47.5 3.3393 54.1568 40.8432
SWR/J both 33.13 3.3393 39.7868 26.4732




  GWAS USING LINEAR MIXED MODELS