Project measure / variable:   Schonfeld1   pct_ITT60

ID, description, units MPD:32315   pct_ITT60   glucose levels as percent of baseline, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast)   [%]  at 60 min  
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
Procedure insulin tolerance
Ontology mappings

  STRAIN COMPARISON PLOT
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Schonfeld1 - glucose levels as percent of baseline, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast) at 60 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means44.9   % 47.3   %
Median of the strain means45.9   % 45.5   %
SD of the strain means± 11.9 ± 15.9
Coefficient of variation (CV)0.264 0.337
Min–max range of strain means25.7   –   59.7   % 24.8   –   71.9   %
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 296.2988 296.2988 2.5814 0.1125
strain 8 13892.1669 1736.5209 15.1291 < 0.0001
sex:strain 8 1817.4682 227.1835 1.9793 0.0613
Residuals 72 8264.164 114.7801


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 28.6 8.12   5 3.63 0.284 21.5, 42.1 -1.38
129X1/SvJ m 25.7 9.81   5 4.39 0.381 15.8, 36.3 -1.36
AKR/J f 56.8 3.44   5 1.54 0.0606 53.4, 61.1 1.0
BALB/cByJ f 46.6 12.5   5 5.59 0.268 32.1, 58.4 0.14
BALB/cByJ m 71.9 14.3   5 6.38 0.199 56.7, 95.2 1.55
C3H/HeJ f 45.1 6.99   5 3.12 0.155 36.0, 50.8 0.01
C3H/HeJ m 45.5 10.8   5 4.82 0.237 33.1, 60.0 -0.11
C57BL/6ByJ f 59.1 5.13   5 2.3 0.0868 53.1, 67.3 1.19
C57BL/6ByJ m 59.2 18.8   5 8.4 0.317 36.4, 88.8 0.75
C57BL/6J f 38.5 7.59   5 3.4 0.197 30.7, 48.1 -0.54
C57BL/6J m 41.2 4.97   5 2.22 0.121 35.5, 46.7 -0.38
DBA/1LacJ f 59.7 18.2   5 8.13 0.304 44.1, 90.4 1.24
DBA/1LacJ m 61.7 10.9   5 4.87 0.177 50.8, 74.4 0.91
NZB/BlNJ f 48.4 10.3   5 4.6 0.213 32.6, 58.3 0.29
NZB/BlNJ m 42.3 6.81   5 3.05 0.161 30.5, 47.4 -0.31
PL/J f 40.9 7.24   5 3.24 0.177 32.5, 49.7 -0.34
PL/J m 53.1 14.6   5 6.55 0.276 35.3, 73.1 0.37
SWR/J f 25.7 6.33   5 2.83 0.246 15.3, 31.5 -1.62
SWR/J m 24.8 3.04   5 1.36 0.123 20.3, 28.5 -1.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 28.58 4.7912 38.1312 19.0288
129X1/SvJ m 25.72 4.7912 35.2712 16.1688
BALB/cByJ f 46.64 4.7912 56.1912 37.0888
BALB/cByJ m 71.9 4.7912 81.4512 62.3488
C3H/HeJ f 45.14 4.7912 54.6912 35.5888
C3H/HeJ m 45.46 4.7912 55.0112 35.9088
C57BL/6ByJ f 59.14 4.7912 68.6912 49.5888
C57BL/6ByJ m 59.2 4.7912 68.7512 49.6488
C57BL/6J f 38.5 4.7912 48.0512 28.9488
C57BL/6J m 41.16 4.7912 50.7112 31.6088
DBA/1LacJ f 59.7 4.7912 69.2512 50.1488
DBA/1LacJ m 61.68 4.7912 71.2312 52.1288
NZB/BlNJ f 48.38 4.7912 57.9312 38.8288
NZB/BlNJ m 42.3 4.7912 51.8512 32.7488
PL/J f 40.86 4.7912 50.4112 31.3088
PL/J m 53.12 4.7912 62.6712 43.5688
SWR/J f 25.7 4.7912 35.2512 16.1488
SWR/J m 24.76 4.7912 34.3112 15.2088


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 27.15 3.3879 33.9037 20.3963
BALB/cByJ both 59.27 3.3879 66.0237 52.5163
C3H/HeJ both 45.3 3.3879 52.0537 38.5463
C57BL/6ByJ both 59.17 3.3879 65.9237 52.4163
C57BL/6J both 39.83 3.3879 46.5837 33.0763
DBA/1LacJ both 60.69 3.3879 67.4437 53.9363
NZB/BlNJ both 45.34 3.3879 52.0937 38.5863
PL/J both 46.99 3.3879 53.7437 40.2363
SWR/J both 25.23 3.3879 31.9837 18.4763




  GWAS USING LINEAR MIXED MODELS