Project measure / variable:   Schonfeld1   pct_ITT30

ID, description, units MPD:32314   pct_ITT30   glucose levels as percent of baseline, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast)   [%]  at 30 min  
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
Procedure insulin tolerance
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  STRAIN COMPARISON PLOT
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Schonfeld1 - glucose levels as percent of baseline, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast) at 30 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means53.2   % 59.8   %
Median of the strain means51.5   % 59.0   %
SD of the strain means± 8.37 ± 14.5
Coefficient of variation (CV)0.157 0.243
Min–max range of strain means43.1   –   67.3   % 39.8   –   88.0   %
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1426.4321 1426.4321 23.1338 < 0.0001
strain 8 7179.442 897.4303 14.5545 < 0.0001
sex:strain 8 3645.5269 455.6909 7.3904 < 0.0001
Residuals 72 4439.528 61.6601


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 43.1 3.74   5 1.67 0.0867 39.6, 48.9 -1.2
129X1/SvJ m 39.8 6.48   5 2.9 0.163 31.4, 47.5 -1.38
AKR/J f 65.1 3.05   5 1.36 0.0469 61.3, 68.5 1.43
BALB/cByJ f 46.6 13.8   5 6.18 0.297 29.4, 65.6 -0.78
BALB/cByJ m 64.9 6.2   5 2.77 0.0955 56.8, 72.3 0.35
C3H/HeJ f 48.6 2.7   5 1.21 0.0555 45.0, 52.3 -0.54
C3H/HeJ m 88.0 6.6   5 2.95 0.0749 82.0, 99.0 1.94
C57BL/6ByJ f 67.3 4.12   5 1.84 0.0612 61.0, 72.4 1.69
C57BL/6ByJ m 71.2 14.1   5 6.31 0.198 55.1, 92.8 0.78
C57BL/6J f 50.7 5.54   5 2.48 0.109 43.0, 57.2 -0.29
C57BL/6J m 51.9 7.49   5 3.35 0.144 42.2, 61.7 -0.54
DBA/1LacJ f 52.2 8.8   5 3.94 0.169 43.7, 65.2 -0.11
DBA/1LacJ m 59.0 9.13   5 4.08 0.155 50.3, 69.4 -0.06
NZB/BlNJ f 58.1 3.13   5 1.4 0.0539 55.1, 63.0 0.59
NZB/BlNJ m 55.7 3.85   5 1.72 0.0692 49.6, 59.3 -0.28
PL/J f 55.9 7.28   5 3.26 0.13 45.0, 64.9 0.33
PL/J m 63.6 11.6   5 5.17 0.182 49.0, 77.5 0.26
SWR/J f 44.0 8.98   5 4.01 0.204 36.0, 55.0 -1.09
SWR/J m 44.1 4.19   5 1.88 0.0952 36.9, 47.8 -1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 43.12 3.5117 50.1204 36.1196
129X1/SvJ m 39.84 3.5117 46.8404 32.8396
BALB/cByJ f 46.6 3.5117 53.6004 39.5996
BALB/cByJ m 64.92 3.5117 71.9204 57.9196
C3H/HeJ f 48.58 3.5117 55.5804 41.5796
C3H/HeJ m 88.0 3.5117 95.0004 80.9996
C57BL/6ByJ f 67.32 3.5117 74.3204 60.3196
C57BL/6ByJ m 71.22 3.5117 78.2204 64.2196
C57BL/6J f 50.7 3.5117 57.7004 43.6996
C57BL/6J m 51.94 3.5117 58.9404 44.9396
DBA/1LacJ f 52.24 3.5117 59.2404 45.2396
DBA/1LacJ m 59.02 3.5117 66.0204 52.0196
NZB/BlNJ f 58.14 3.5117 65.1404 51.1396
NZB/BlNJ m 55.66 3.5117 62.6604 48.6596
PL/J f 55.92 3.5117 62.9204 48.9196
PL/J m 63.64 3.5117 70.6404 56.6396
SWR/J f 44.02 3.5117 51.0204 37.0196
SWR/J m 44.06 3.5117 51.0604 37.0596


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 41.48 2.4831 46.4301 36.5299
BALB/cByJ both 55.76 2.4831 60.7101 50.8099
C3H/HeJ both 68.29 2.4831 73.2401 63.3399
C57BL/6ByJ both 69.27 2.4831 74.2201 64.3199
C57BL/6J both 51.32 2.4831 56.2701 46.3699
DBA/1LacJ both 55.63 2.4831 60.5801 50.6799
NZB/BlNJ both 56.9 2.4831 61.8501 51.9499
PL/J both 59.78 2.4831 64.7301 54.8299
SWR/J both 44.04 2.4831 48.9901 39.0899




  GWAS USING LINEAR MIXED MODELS