Phenotype measure:   Schonfeld1   AUC_GTT2

ID, description, units MPD:32309   AUC_GTT2   glucose levels, area under curve, glucose tolerance test (10% glucose i.p., 5h fast)   [AUC]  0 to 120 min
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
Procedure glucose tolerance
Ontology mappings

  STRAIN COMPARISON PLOT
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Schonfeld1 - glucose levels, area under curve, glucose tolerance test (10% glucose i.p., 5h fast) 0 to 120 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means5278   AUC 4773   AUC
Median of the strain means5610   AUC 4919   AUC
SD of the strain means± 1901 ± 1548
Coefficient of variation (CV)0.360 0.324
Min–max range of strain means2323   –   8733   AUC 2705   –   7108   AUC
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4069164.1 4069164.1 1.4054 0.2397
strain 8 186290086.0889 23286260.7611 8.0424 < 0.0001
sex:strain 8 69399741.2 8674967.65 2.9961 0.0059
Residuals 72 208470466.4 2895423.1444


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 2323.0 883.0   5 395.0 0.38 1290.0, 3585.0 -1.55
129X1/SvJ m 3233.0 1418.0   5 634.0 0.439 2258.0, 5730.0 -0.99
AKR/J f 6000.0 1724.0   5 771.0 0.287 3990.0, 8430.0 0.38
BALB/cByJ f 6924.0 867.0   5 388.0 0.125 5490.0, 7695.0 0.87
BALB/cByJ m 5160.0 864.0   5 386.0 0.167 4350.0, 6345.0 0.25
C3H/HeJ f 2786.0 748.0   5 335.0 0.269 1949.0, 3771.0 -1.31
C3H/HeJ m 5140.0 1279.0   5 572.0 0.249 3810.0, 7215.0 0.24
C57BL/6ByJ f 4761.0 2049.0   5 916.0 0.43 3045.0, 8325.0 -0.27
C57BL/6ByJ m 4272.0 2710.0   5 1212.0 0.634 1500.0, 7950.0 -0.32
C57BL/6J f 8733.0 1427.0   5 638.0 0.163 7320.0, 10800.0 1.82
C57BL/6J m 7108.0 1061.0   5 475.0 0.149 5835.0, 8085.0 1.51
DBA/1LacJ f 5499.0 3191.0   5 1427.0 0.58 2340.0, 10095.0 0.12
DBA/1LacJ m 3456.0 1628.0   5 728.0 0.471 2115.0, 6180.0 -0.85
NZB/BlNJ f 5720.0 1231.0   5 551.0 0.215 3840.0, 6910.0 0.23
NZB/BlNJ m 6960.0 1330.0   5 595.0 0.191 4860.0, 8430.0 1.41
PL/J f 4074.0 2188.0   5 979.0 0.537 840.0, 6135.0 -0.63
PL/J m 4919.0 2305.0   5 1031.0 0.469 2505.0, 8625.0 0.09
SWR/J f 5961.0 1849.0   5 827.0 0.31 3135.0, 7785.0 0.36
SWR/J m 2705.0 1135.0   5 508.0 0.42 1275.0, 4005.0 -1.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 2322.6 760.9761 3839.5781 805.6219
129X1/SvJ m 3233.0 760.9761 4749.9781 1716.0219
BALB/cByJ f 6924.0 760.9761 8440.9781 5407.0219
BALB/cByJ m 5160.0 760.9761 6676.9781 3643.0219
C3H/HeJ f 2785.8 760.9761 4302.7781 1268.8219
C3H/HeJ m 5140.0 760.9761 6656.9781 3623.0219
C57BL/6ByJ f 4761.0 760.9761 6277.9781 3244.0219
C57BL/6ByJ m 4272.0 760.9761 5788.9781 2755.0219
C57BL/6J f 8733.0 760.9761 10249.9781 7216.0219
C57BL/6J m 7108.4 760.9761 8625.3781 5591.4219
DBA/1LacJ f 5499.0 760.9761 7015.9781 3982.0219
DBA/1LacJ m 3456.0 760.9761 4972.9781 1939.0219
NZB/BlNJ f 5720.0 760.9761 7236.9781 4203.0219
NZB/BlNJ m 6960.0 760.9761 8476.9781 5443.0219
PL/J f 4074.0 760.9761 5590.9781 2557.0219
PL/J m 4918.6 760.9761 6435.5781 3401.6219
SWR/J f 5961.0 760.9761 7477.9781 4444.0219
SWR/J m 2705.0 760.9761 4221.9781 1188.0219


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 2777.8 538.0914 3850.4655 1705.1345
BALB/cByJ both 6042.0 538.0914 7114.6655 4969.3345
C3H/HeJ both 3962.9 538.0914 5035.5655 2890.2345
C57BL/6ByJ both 4516.5 538.0914 5589.1655 3443.8345
C57BL/6J both 7920.7 538.0914 8993.3655 6848.0345
DBA/1LacJ both 4477.5 538.0914 5550.1655 3404.8345
NZB/BlNJ both 6340.0 538.0914 7412.6655 5267.3345
PL/J both 4496.3 538.0914 5568.9655 3423.6345
SWR/J both 4333.0 538.0914 5405.6655 3260.3345




  GWAS USING LINEAR MIXED MODELS