Phenotype measure:   Schonfeld1   AUC_GTT1

ID, description, units MPD:32308   AUC_GTT1   glucose levels, area under curve, glucose tolerance test (10% glucose i.p., 5h fast)   [AUC]  0 to 60 min
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
Procedure glucose tolerance
Ontology mappings

  STRAIN COMPARISON PLOT
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Schonfeld1 - glucose levels, area under curve, glucose tolerance test (10% glucose i.p., 5h fast) 0 to 60 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means2944   AUC 3479   AUC
Median of the strain means2595   AUC 3481   AUC
SD of the strain means± 1224 ± 1025
Coefficient of variation (CV)0.416 0.295
Min–max range of strain means1613   –   5230   AUC 1894   –   5088   AUC
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6272112.0111 6272112.0111 8.4176 0.0049
strain 8 95978266.0 11997283.25 16.1011 < 0.0001
sex:strain 8 13454687.6889 1681835.9611 2.2571 0.0327
Residuals 72 53648793.2 745122.1278


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 1656.0 522.0   5 233.0 0.315 1035.0, 2205.0 -1.05
129X1/SvJ m 1894.0 796.0   5 356.0 0.42 855.0, 2940.0 -1.55
AKR/J f 2886.0 789.0   5 353.0 0.273 2070.0, 4110.0 -0.05
BALB/cByJ f 4218.0 630.0   5 282.0 0.149 3570.0, 5160.0 1.04
BALB/cByJ m 3870.0 971.0   5 434.0 0.251 2940.0, 5355.0 0.38
C3H/HeJ f 1613.0 541.0   5 242.0 0.335 926.0, 2394.0 -1.09
C3H/HeJ m 2419.0 763.0   5 341.0 0.316 1230.0, 3285.0 -1.03
C57BL/6ByJ f 1958.0 949.0   5 425.0 0.485 1020.0, 3525.0 -0.81
C57BL/6ByJ m 3859.0 867.0   5 388.0 0.225 2700.0, 4740.0 0.37
C57BL/6J f 5230.0 1195.0   5 534.0 0.228 4312.0, 7170.0 1.87
C57BL/6J m 4598.0 1093.0   5 489.0 0.238 3128.0, 5865.0 1.09
DBA/1LacJ f 2175.0 944.0   5 422.0 0.434 1020.0, 3510.0 -0.63
DBA/1LacJ m 2688.0 554.0   5 248.0 0.206 2205.0, 3510.0 -0.77
NZB/BlNJ f 3907.0 883.0   5 395.0 0.226 2580.0, 5040.0 0.79
NZB/BlNJ m 5088.0 1036.0   5 463.0 0.204 4350.0, 6870.0 1.57
PL/J f 2304.0 823.0   5 368.0 0.357 1140.0, 3135.0 -0.52
PL/J m 3481.0 864.0   5 386.0 0.248 2490.0, 4815.0 0.0
SWR/J f 3495.0 720.0   5 322.0 0.206 2295.0, 4155.0 0.45
SWR/J m 3411.0 1011.0   5 452.0 0.296 2400.0, 4680.0 -0.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 1656.0 386.0368 2425.5503 886.4497
129X1/SvJ m 1894.4 386.0368 2663.9503 1124.8497
BALB/cByJ f 4218.0 386.0368 4987.5503 3448.4497
BALB/cByJ m 3870.0 386.0368 4639.5503 3100.4497
C3H/HeJ f 1613.0 386.0368 2382.5503 843.4497
C3H/HeJ m 2418.6 386.0368 3188.1503 1649.0497
C57BL/6ByJ f 1957.6 386.0368 2727.1503 1188.0497
C57BL/6ByJ m 3858.6 386.0368 4628.1503 3089.0497
C57BL/6J f 5229.8 386.0368 5999.3503 4460.2497
C57BL/6J m 4597.6 386.0368 5367.1503 3828.0497
DBA/1LacJ f 2175.0 386.0368 2944.5503 1405.4497
DBA/1LacJ m 2688.0 386.0368 3457.5503 1918.4497
NZB/BlNJ f 3907.4 386.0368 4676.9503 3137.8497
NZB/BlNJ m 5088.0 386.0368 5857.5503 4318.4497
PL/J f 2304.0 386.0368 3073.5503 1534.4497
PL/J m 3481.4 386.0368 4250.9503 2711.8497
SWR/J f 3495.0 386.0368 4264.5503 2725.4497
SWR/J m 3411.0 386.0368 4180.5503 2641.4497


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 1775.2 272.9693 2319.3543 1231.0457
BALB/cByJ both 4044.0 272.9693 4588.1543 3499.8457
C3H/HeJ both 2015.8 272.9693 2559.9543 1471.6457
C57BL/6ByJ both 2908.1 272.9693 3452.2543 2363.9457
C57BL/6J both 4913.7 272.9693 5457.8543 4369.5457
DBA/1LacJ both 2431.5 272.9693 2975.6543 1887.3457
NZB/BlNJ both 4497.7 272.9693 5041.8543 3953.5457
PL/J both 2892.7 272.9693 3436.8543 2348.5457
SWR/J both 3453.0 272.9693 3997.1543 2908.8457




  GWAS USING LINEAR MIXED MODELS