Project measure / variable:   Paigen1   gs

ID, description, units MPD:2917   gs   gallbladder, number of true gallstones   [n]  
high-fat diet study
Data set, strains Paigen1   inbred   43 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen1 - gallbladder, number of true gallstones



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains42 strains
Mean of the strain means0.130   n 0.909   n
Median of the strain means0   n 0   n
SD of the strain means± 0.361 ± 2.69
Coefficient of variation (CV)2.77 2.96
Min–max range of strain means0   –   2.10   n 0   –   14.4   n
Mean sample size per strain8.8   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 110.0228 110.0228 11.8222 0.0006
strain 41 1605.0158 39.1467 4.2064 < 0.0001
sex:strain 41 1140.2732 27.8115 2.9884 < 0.0001
Residuals 624 5807.2306 9.3065


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.2 0.422   10 0.133 2.11 0.19
129S1/SvImJ m 0.0 0.0   10 0.0 0.0 -0.34
A/J f 0.6 1.9   10 0.6 3.16 1.3
A/J m 0.0 0.0   10 0.0 0.0 -0.34
AKR/J f 0.0 0.0   9 0.0 0.0 -0.36
AKR/J m 0.0 0.0   9 0.0 0.0 -0.34
BALB/cJ f 0.1 0.316   10 0.1 3.16 -0.08
BALB/cJ m 0.1 0.316   10 0.1 3.16 -0.3
BPH/2J f 0.4 1.26   10 0.4 3.16 0.75
BPH/2J m 0.0 0.0   9 0.0 0.0 -0.34
BPL/1J f 1.0 3.16   10 1.0 3.16 2.41
BPL/1J m 0.0 0.0   10 0.0 0.0 -0.34
BPN/3J f 0.0 0.0   10 0.0 0.0 -0.36
BPN/3J m 0.444 1.33   9 0.444 3.0 -0.17
BTBR T+ Itpr3tf/J f 0.0 0.0   3 0.0 0.0 -0.36
BTBR T+ Itpr3tf/J m 0.0 0.0   10 0.0 0.0 -0.34
C3H/HeJ f 0.0 0.0   9 0.0 0.0 -0.36
C3H/HeJ m 5.2 9.55   5 4.27 1.84 1.6
C57BL/10J f 2.1 6.3   10 1.99 3.0 5.46
C57BL/10J m 14.4 17.6   10 5.57 1.22 5.02
C57BL/6J f 0.0 0.0   10 0.0 0.0 -0.36
C57BL/6J m 2.5 3.27   6 1.34 1.31 0.59
C57BLKS/J f 0.167 0.408   6 0.167 2.45 0.1
C57BLKS/J m 0.0 0.0   5 0.0 0.0 -0.34
C57BR/cdJ f 0.0 0.0   9 0.0 0.0 -0.36
C57BR/cdJ m 0.0 0.0   10 0.0 0.0 -0.34
C57L/J f 0.1 0.316   10 0.1 3.16 -0.08
C57L/J m 0.8 1.32   10 0.416 1.65 -0.04
C58/J f 0.1 0.316   10 0.1 3.16 -0.08
C58/J m 0.4 0.699   10 0.221 1.75 -0.19
CAST/EiJ f 0.0 0.0   5 0.0 0.0 -0.36
CAST/EiJ m 0.0 0.0   9 0.0 0.0 -0.34
CBA/J f 0.0 0.0   9 0.0 0.0 -0.36
CBA/J m 0.7 1.49   10 0.473 2.13 -0.08
CE/J f 0.0 0.0   9 0.0 0.0 -0.36
CE/J m 0.0 0.0   6 0.0 0.0 -0.34
CZECHII/EiJ f 0.0 0.0   7 0.0 0.0 -0.36
CZECHII/EiJ m 0.0 0.0   7 0.0 0.0 -0.34
DBA/1J f 0.1 0.316   10 0.1 3.16 -0.08
DBA/1J m 0.0 0.0   8 0.0 0.0 -0.34
DBA/2J f 0.3 0.675   10 0.213 2.25 0.47
DBA/2J m 0.0 0.0   9 0.0 0.0 -0.34
FVB/NJ f 0.0 0.0   9 0.0 0.0 -0.36
FVB/NJ m 0.0 0.0   3 0.0 0.0 -0.34
I/LnJ f 0.0 0.0   9 0.0 0.0 -0.36
I/LnJ m 0.0 0.0   9 0.0 0.0 -0.34
KK/HlJ f 0.0 0.0   8 0.0 0.0 -0.36
KK/HlJ m 0.0 0.0   9 0.0 0.0 -0.34
LP/J f 0.0 0.0   9 0.0 0.0 -0.36
LP/J m 0.0 0.0   9 0.0 0.0 -0.34
MOLF/EiJ f 0.0 0.0   9 0.0 0.0 -0.36
MOLF/EiJ m 0.0 0.0   9 0.0 0.0 -0.34
NOD/ShiLtJ f 0.0 0.0   8 0.0 0.0 -0.36
NOD/ShiLtJ m 5.0 12.2   6 5.0 2.45 1.52
NON/ShiLtJ f 0.0 0.0   9 0.0 0.0 -0.36
NON/ShiLtJ m 0.0 0.0   10 0.0 0.0 -0.34
NZB/BlNJ f 0.0 0.0   9 0.0 0.0 -0.36
NZB/BlNJ m 0.0 0.0   9 0.0 0.0 -0.34
NZW/LacJ f 0.0 0.0   8 0.0 0.0 -0.36
NZW/LacJ m 0.3 0.949   10 0.3 3.16 -0.23
PERA/EiJ f 0.125 0.354   8 0.125 2.83 -0.01
PERA/EiJ m 0.0 0.0   4 0.0 0.0 -0.34
P/J f 0.0 0.0   9 0.0 0.0 -0.36
P/J m 0.0 0.0   9 0.0 0.0 -0.34
PL/J f 0.0 0.0   10 0.0 0.0 -0.36
PL/J m 0.0 0.0   3 0.0 0.0 -0.34
RBF/DnJ f 0.0 0.0   9 0.0 0.0 -0.36
RBF/DnJ m 0.0 0.0   9 0.0 0.0 -0.34
RF/J f 0.0 0.0   10 0.0 0.0 -0.36
RF/J m 0.0 0.0   5 0.0 0.0 -0.34
RIIIS/J f 0.2 0.632   10 0.2 3.16 0.19
RIIIS/J m 8.0 12.6   9 4.2 1.57 2.64
SEA/GnJ f 0.0 0.0   8 0.0 0.0 -0.36
SEA/GnJ m 0.0 0.0   10 0.0 0.0 -0.34
SJL/J f 0.1 0.316   10 0.1 3.16 -0.08
SJL/J m 0.333 1.0   9 0.333 3.0 -0.21
SM/J f 0.0 0.0   7 0.0 0.0 -0.36
SM/J m 0.0 0.0   5 0.0 0.0 -0.34
SPRET/EiJ f 0.0 0.0   7 0.0 0.0 -0.36
SPRET/EiJ m 0.0 0.0   5 0.0 0.0 -0.34
SWR/J f 0.0 0.0   10 0.0 0.0 -0.36
SWR/J m 0.0 0.0   8 0.0 0.0 -0.34
WSB/EiJ f 0.0 0.0   8 0.0 0.0 -0.36
WSB/EiJ m 0.0 0.0   6 0.0 0.0 -0.34
YBR/EiJ f 0.0 0.0   3 0.0 0.0 -0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2 0.9647 2.0945 -1.6945
129S1/SvImJ m 0.0 0.9647 1.8945 -1.8945
A/J f 0.6 0.9647 2.4945 -1.2945
A/J m 0.0 0.9647 1.8945 -1.8945
AKR/J f 0.0 1.0169 1.9969 -1.9969
AKR/J m 0.0 1.0169 1.9969 -1.9969
BALB/cJ f 0.1 0.9647 1.9945 -1.7945
BALB/cJ m 0.1 0.9647 1.9945 -1.7945
BPH/2J f 0.4 0.9647 2.2945 -1.4945
BPH/2J m 0.0 1.0169 1.9969 -1.9969
BPL/1J f 1.0 0.9647 2.8945 -0.8945
BPL/1J m 0.0 0.9647 1.8945 -1.8945
BPN/3J f 0.0 0.9647 1.8945 -1.8945
BPN/3J m 0.4444 1.0169 2.4414 -1.5525
BTBR T+ Itpr3tf/J f 0.0 1.7613 3.4588 -3.4588
BTBR T+ Itpr3tf/J m 0.0 0.9647 1.8945 -1.8945
C3H/HeJ f 0.0 1.0169 1.9969 -1.9969
C3H/HeJ m 5.2 1.3643 7.8792 2.5208
C57BL/10J f 2.1 0.9647 3.9945 0.2055
C57BL/10J m 14.4 0.9647 16.2945 12.5055
C57BL/6J f 0.0 0.9647 1.8945 -1.8945
C57BL/6J m 2.5 1.2454 4.9457 0.0543
C57BLKS/J f 0.1667 1.2454 2.6124 -2.2791
C57BLKS/J m 0.0 1.3643 2.6792 -2.6792
C57BR/cdJ f 0.0 1.0169 1.9969 -1.9969
C57BR/cdJ m 0.0 0.9647 1.8945 -1.8945
C57L/J f 0.1 0.9647 1.9945 -1.7945
C57L/J m 0.8 0.9647 2.6945 -1.0945
C58/J f 0.1 0.9647 1.9945 -1.7945
C58/J m 0.4 0.9647 2.2945 -1.4945
CAST/EiJ f 0.0 1.3643 2.6792 -2.6792
CAST/EiJ m 0.0 1.0169 1.9969 -1.9969
CBA/J f 0.0 1.0169 1.9969 -1.9969
CBA/J m 0.7 0.9647 2.5945 -1.1945
CE/J f 0.0 1.0169 1.9969 -1.9969
CE/J m 0.0 1.2454 2.4457 -2.4457
CZECHII/EiJ f 0.0 1.153 2.2643 -2.2643
CZECHII/EiJ m 0.0 1.153 2.2643 -2.2643
DBA/1J f 0.1 0.9647 1.9945 -1.7945
DBA/1J m 0.0 1.0786 2.1181 -2.1181
DBA/2J f 0.3 0.9647 2.1945 -1.5945
DBA/2J m 0.0 1.0169 1.9969 -1.9969
FVB/NJ f 0.0 1.0169 1.9969 -1.9969
FVB/NJ m 0.0 1.7613 3.4588 -3.4588
I/LnJ f 0.0 1.0169 1.9969 -1.9969
I/LnJ m 0.0 1.0169 1.9969 -1.9969
KK/HlJ f 0.0 1.0786 2.1181 -2.1181
KK/HlJ m 0.0 1.0169 1.9969 -1.9969
LP/J f 0.0 1.0169 1.9969 -1.9969
LP/J m 0.0 1.0169 1.9969 -1.9969
MOLF/EiJ f 0.0 1.0169 1.9969 -1.9969
MOLF/EiJ m 0.0 1.0169 1.9969 -1.9969
NOD/ShiLtJ f 0.0 1.0786 2.1181 -2.1181
NOD/ShiLtJ m 5.0 1.2454 7.4457 2.5543
NON/ShiLtJ f 0.0 1.0169 1.9969 -1.9969
NON/ShiLtJ m 0.0 0.9647 1.8945 -1.8945
NZB/BlNJ f 0.0 1.0169 1.9969 -1.9969
NZB/BlNJ m 0.0 1.0169 1.9969 -1.9969
NZW/LacJ f 0.0 1.0786 2.1181 -2.1181
NZW/LacJ m 0.3 0.9647 2.1945 -1.5945
PERA/EiJ f 0.125 1.0786 2.2431 -1.9931
PERA/EiJ m 0.0 1.5253 2.9954 -2.9954
P/J f 0.0 1.0169 1.9969 -1.9969
P/J m 0.0 1.0169 1.9969 -1.9969
PL/J f 0.0 0.9647 1.8945 -1.8945
PL/J m 0.0 1.7613 3.4588 -3.4588
RBF/DnJ f 0.0 1.0169 1.9969 -1.9969
RBF/DnJ m 0.0 1.0169 1.9969 -1.9969
RF/J f 0.0 0.9647 1.8945 -1.8945
RF/J m 0.0 1.3643 2.6792 -2.6792
RIIIS/J f 0.2 0.9647 2.0945 -1.6945
RIIIS/J m 8.0 1.0169 9.9969 6.0031
SEA/GnJ f 0.0 1.0786 2.1181 -2.1181
SEA/GnJ m 0.0 0.9647 1.8945 -1.8945
SJL/J f 0.1 0.9647 1.9945 -1.7945
SJL/J m 0.3333 1.0169 2.3303 -1.6636
SM/J f 0.0 1.153 2.2643 -2.2643
SM/J m 0.0 1.3643 2.6792 -2.6792
SPRET/EiJ f 0.0 1.153 2.2643 -2.2643
SPRET/EiJ m 0.0 1.3643 2.6792 -2.6792
SWR/J f 0.0 0.9647 1.8945 -1.8945
SWR/J m 0.0 1.0786 2.1181 -2.1181
WSB/EiJ f 0.0 1.0786 2.1181 -2.1181
WSB/EiJ m 0.0 1.2454 2.4457 -2.4457


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.1 0.6821 1.4396 -1.2396
A/J both 0.3 0.6821 1.6396 -1.0396
AKR/J both 0.0 0.719 1.412 -1.412
BALB/cJ both 0.1 0.6821 1.4396 -1.2396
BPH/2J both 0.2 0.7008 1.5763 -1.1763
BPL/1J both 0.5 0.6821 1.8396 -0.8396
BPN/3J both 0.2222 0.7008 1.5985 -1.1541
BTBR T+ Itpr3tf/J both 0.0 1.0041 1.9718 -1.9718
C3H/HeJ both 2.6 0.8508 4.2707 0.9293
C57BL/10J both 8.25 0.6821 9.5896 6.9104
C57BL/6J both 1.25 0.7877 2.7968 -0.2968
C57BLKS/J both 0.0833 0.9236 1.8971 -1.7305
C57BR/cdJ both 0.0 0.7008 1.3763 -1.3763
C57L/J both 0.45 0.6821 1.7896 -0.8896
C58/J both 0.25 0.6821 1.5896 -1.0896
CAST/EiJ both 0.0 0.8508 1.6707 -1.6707
CBA/J both 0.35 0.7008 1.7263 -1.0263
CE/J both 0.0 0.8039 1.5787 -1.5787
CZECHII/EiJ both 0.0 0.8153 1.6011 -1.6011
DBA/1J both 0.05 0.7235 1.4708 -1.3708
DBA/2J both 0.15 0.7008 1.5263 -1.2263
FVB/NJ both 0.0 1.0169 1.9969 -1.9969
I/LnJ both 0.0 0.719 1.412 -1.412
KK/HlJ both 0.0 0.7412 1.4555 -1.4555
LP/J both 0.0 0.719 1.412 -1.412
MOLF/EiJ both 0.0 0.719 1.412 -1.412
NOD/ShiLtJ both 2.5 0.8238 4.1177 0.8823
NON/ShiLtJ both 0.0 0.7008 1.3763 -1.3763
NZB/BlNJ both 0.0 0.719 1.412 -1.412
NZW/LacJ both 0.15 0.7235 1.5708 -1.2708
PERA/EiJ both 0.0625 0.9341 1.8968 -1.7718
P/J both 0.0 0.719 1.412 -1.412
PL/J both 0.0 1.0041 1.9718 -1.9718
RBF/DnJ both 0.0 0.719 1.412 -1.412
RF/J both 0.0 0.8355 1.6406 -1.6406
RIIIS/J both 4.1 0.7008 5.4763 2.7237
SEA/GnJ both 0.0 0.7235 1.4208 -1.4208
SJL/J both 0.2167 0.7008 1.593 -1.1596
SM/J both 0.0 0.8931 1.7539 -1.7539
SPRET/EiJ both 0.0 0.8931 1.7539 -1.7539
SWR/J both 0.0 0.7235 1.4208 -1.4208
WSB/EiJ both 0.0 0.8238 1.6177 -1.6177




  GWAS USING LINEAR MIXED MODELS