Phenotype measure:   Paigen1   fusedLC

ID, description, units MPD:2914   fusedLC   gallbladder, fused liquid crystals (score: 0-4)   [score]
high-fat diet study
Data set, strains Paigen1   inbred   43 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Paigen1 - gallbladder, fused liquid crystals (score: 0-4)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains42 strains
Mean of the strain means0.687   score 0.504   score
Median of the strain means0.611   score 0.447   score
SD of the strain means± 0.480 ± 0.390
Coefficient of variation (CV)0.698 0.774
Min–max range of strain means0   –   2.17   score 0   –   1.80   score
Mean sample size per strain8.8   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.7791 2.7791 7.6644 0.0058
strain 41 95.5998 2.3317 6.4306 < 0.0001
sex:strain 41 33.4682 0.8163 2.2513 < 0.0001
Residuals 622 225.5353 0.3626


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.15 0.337   10 0.107 2.25 -1.12
129S1/SvImJ m 0.3 0.422   10 0.133 1.41 -0.52
A/J f 1.45 0.762   10 0.241 0.525 0.5, 3.0 1.59
A/J m 0.2 0.258   10 0.0816 1.29 -0.78
AKR/J f 0.722 0.565   9 0.188 0.783 0.07
AKR/J m 0.611 0.858   9 0.286 1.4 0.27
BALB/cJ f 0.2 0.35   10 0.111 1.75 -1.02
BALB/cJ m 0.05 0.158   10 0.05 3.16 -1.16
BPH/2J f 0.55 0.497   10 0.157 0.904 -0.29
BPH/2J m 0.389 0.22   9 0.0735 0.567 -0.29
BPL/1J f 0.8 0.753   10 0.238 0.941 0.24
BPL/1J m 0.5 0.471   10 0.149 0.943 -0.01
BPN/3J f 0.2 0.35   10 0.111 1.75 -1.02
BPN/3J m 0.611 0.333   9 0.111 0.545 0.27
BTBR T+ Itpr3tf/J f 2.17 2.47   3 1.42 1.14 0.5, 5.0 3.09
BTBR T+ Itpr3tf/J m 0.9 0.876   10 0.277 0.973 1.01
C3H/HeJ f 1.11 1.05   9 0.351 0.949 0.88
C3H/HeJ m 0.0 0.0   5 0.0 0.0 -1.29
C57BL/10J f 0.2 0.258   10 0.0816 1.29 -1.02
C57BL/10J m 1.4 1.22   10 0.386 0.872 0.5, 4.0 2.3
C57BL/6J f 0.9 0.738   10 0.233 0.82 0.44
C57BL/6J m 0.333 0.516   6 0.211 1.55 -0.44
C57BLKS/J f 0.667 0.753   6 0.307 1.13 -0.04
C57BLKS/J m 0.3 0.447   5 0.2 1.49 -0.52
C57BR/cdJ f 1.17 0.866   9 0.289 0.742 1.01
C57BR/cdJ m 0.45 0.438   10 0.138 0.973 -0.14
C57L/J f 1.8 0.632   10 0.2 0.351 1.0, 3.0 2.32
C57L/J m 1.8 0.422   10 0.133 0.234 1.0, 2.0 3.32
C58/J f 1.55 0.864   10 0.273 0.558 0.5, 3.0 1.8
C58/J m 0.95 0.438   10 0.138 0.461 0.5, 2.0 1.14
CAST/EiJ f 0.5 0.5   5 0.224 1.0 -0.39
CAST/EiJ m 0.167 0.354   9 0.118 2.12 -0.86
CBA/J f 1.11 0.858   9 0.286 0.772 0.5, 3.0 0.88
CBA/J m 0.5 0.707   10 0.224 1.41 -0.01
CE/J f 0.444 1.01   9 0.338 2.28 -0.51
CE/J m 0.25 0.418   6 0.171 1.67 -0.65
CZECHII/EiJ f 0.571 0.732   7 0.277 1.28 -0.24
CZECHII/EiJ m 0.714 0.267   7 0.101 0.374 0.5, 1.0 0.54
DBA/1J f 0.5 0.667   10 0.211 1.33 -0.39
DBA/1J m 0.438 0.729   8 0.258 1.67 -0.17
DBA/2J f 0.0 0.0   10 0.0 0.0 -1.43
DBA/2J m 0.0 0.0   9 0.0 0.0 -1.29
FVB/NJ f 0.778 0.795   9 0.265 1.02 0.19
FVB/NJ m 0.5 0.5   3 0.289 1.0 -0.01
I/LnJ f 0.389 0.486   9 0.162 1.25 -0.62
I/LnJ m 0.556 0.391   9 0.13 0.704 0.13
KK/HlJ f 0.125 0.354   8 0.125 2.83 -1.17
KK/HlJ m 0.278 0.363   9 0.121 1.31 -0.58
LP/J f 0.778 0.363   9 0.121 0.467 0.19
LP/J m 0.5 0.707   9 0.236 1.41 -0.01
MOLF/EiJ f 0.611 0.486   9 0.162 0.795 -0.16
MOLF/EiJ m 0.667 0.5   9 0.167 0.75 0.42
NOD/ShiLtJ f 0.625 0.694   8 0.245 1.11 -0.13
NOD/ShiLtJ m 0.583 0.492   6 0.201 0.843 0.2
NON/ShiLtJ f 0.444 0.391   9 0.13 0.879 -0.51
NON/ShiLtJ m 0.111 0.333   9 0.111 3.0 -1.01
NZB/BlNJ f 0.944 0.726   9 0.242 0.769 0.54
NZB/BlNJ m 0.444 0.527   9 0.176 1.19 -0.15
NZW/LacJ f 1.31 1.22   8 0.432 0.932 1.3
NZW/LacJ m 1.11 1.05   9 0.351 0.949 1.55
PERA/EiJ f 0.0625 0.177   8 0.0625 2.83 -1.3
PERA/EiJ m 0.0 0.0   4 0.0 0.0 -1.29
P/J f 0.667 0.354   9 0.118 0.53 -0.04
P/J m 0.722 0.618   9 0.206 0.856 0.56
PL/J f 0.5 0.667   10 0.211 1.33 -0.39
PL/J m 0.0 0.0   3 0.0 0.0 -1.29
RBF/DnJ f 0.444 0.527   9 0.176 1.19 -0.51
RBF/DnJ m 0.222 0.363   9 0.121 1.63 -0.72
RF/J f 0.5 0.707   10 0.224 1.41 -0.39
RF/J m 0.3 0.274   5 0.122 0.913 -0.52
RIIIS/J f 0.95 0.438   10 0.138 0.461 0.5, 2.0 0.55
RIIIS/J m 0.944 0.635   9 0.212 0.672 0.5, 2.0 1.13
SEA/GnJ f 1.19 0.53   8 0.187 0.447 0.5, 2.0 1.05
SEA/GnJ m 0.85 0.58   10 0.183 0.682 0.89
SJL/J f 0.1 0.211   10 0.0667 2.11 -1.22
SJL/J m 0.333 0.433   9 0.144 1.3 -0.44
SM/J f 0.0714 0.189   7 0.0714 2.65 -1.28
SM/J m 0.2 0.274   5 0.122 1.37 -0.78
SPRET/EiJ f 0.429 0.535   7 0.202 1.25 -0.54
SPRET/EiJ m 0.2 0.274   5 0.122 1.37 -0.78
SWR/J f 0.7 0.422   10 0.133 0.602 0.03
SWR/J m 1.12 0.641   8 0.227 0.57 1.58
WSB/EiJ f 0.5 0.378   8 0.134 0.756 -0.39
WSB/EiJ m 0.667 0.516   6 0.211 0.775 0.42
YBR/EiJ f 0.667 0.577   3 0.333 0.866 -0.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.15 0.1904 0.5239 -0.2239
129S1/SvImJ m 0.3 0.1904 0.6739 -0.0739
A/J f 1.45 0.1904 1.8239 1.0761
A/J m 0.2 0.1904 0.5739 -0.1739
AKR/J f 0.7222 0.2007 1.1164 0.3281
AKR/J m 0.6111 0.2007 1.0053 0.2169
BALB/cJ f 0.2 0.1904 0.5739 -0.1739
BALB/cJ m 0.05 0.1904 0.4239 -0.3239
BPH/2J f 0.55 0.1904 0.9239 0.1761
BPH/2J m 0.3889 0.2007 0.7831 -0.0053
BPL/1J f 0.8 0.1904 1.1739 0.4261
BPL/1J m 0.5 0.1904 0.8739 0.1261
BPN/3J f 0.2 0.1904 0.5739 -0.1739
BPN/3J m 0.6111 0.2007 1.0053 0.2169
BTBR T+ Itpr3tf/J f 2.1667 0.3477 2.8494 1.4839
BTBR T+ Itpr3tf/J m 0.9 0.1904 1.2739 0.5261
C3H/HeJ f 1.1111 0.2007 1.5053 0.7169
C3H/HeJ m 0.0 0.2693 0.5288 -0.5288
C57BL/10J f 0.2 0.1904 0.5739 -0.1739
C57BL/10J m 1.4 0.1904 1.7739 1.0261
C57BL/6J f 0.9 0.1904 1.2739 0.5261
C57BL/6J m 0.3333 0.2458 0.8161 -0.1494
C57BLKS/J f 0.6667 0.2458 1.1494 0.1839
C57BLKS/J m 0.3 0.2693 0.8288 -0.2288
C57BR/cdJ f 1.1667 0.2007 1.5608 0.7725
C57BR/cdJ m 0.45 0.1904 0.8239 0.0761
C57L/J f 1.8 0.1904 2.1739 1.4261
C57L/J m 1.8 0.1904 2.1739 1.4261
C58/J f 1.55 0.1904 1.9239 1.1761
C58/J m 0.95 0.1904 1.3239 0.5761
CAST/EiJ f 0.5 0.2693 1.0288 -0.0288
CAST/EiJ m 0.1667 0.2007 0.5608 -0.2275
CBA/J f 1.1111 0.2007 1.5053 0.7169
CBA/J m 0.5 0.1904 0.8739 0.1261
CE/J f 0.4444 0.2007 0.8386 0.0503
CE/J m 0.25 0.2458 0.7328 -0.2328
CZECHII/EiJ f 0.5714 0.2276 1.0184 0.1245
CZECHII/EiJ m 0.7143 0.2276 1.1612 0.2673
DBA/1J f 0.5 0.1904 0.8739 0.1261
DBA/1J m 0.4375 0.2129 0.8556 0.0194
DBA/2J f 0.0 0.1904 0.3739 -0.3739
DBA/2J m 0.0 0.2007 0.3942 -0.3942
FVB/NJ f 0.7778 0.2007 1.1719 0.3836
FVB/NJ m 0.5 0.3477 1.1827 -0.1827
I/LnJ f 0.3889 0.2007 0.7831 -0.0053
I/LnJ m 0.5556 0.2007 0.9497 0.1614
KK/HlJ f 0.125 0.2129 0.5431 -0.2931
KK/HlJ m 0.2778 0.2007 0.6719 -0.1164
LP/J f 0.7778 0.2007 1.1719 0.3836
LP/J m 0.5 0.2007 0.8942 0.1058
MOLF/EiJ f 0.6111 0.2007 1.0053 0.2169
MOLF/EiJ m 0.6667 0.2007 1.0608 0.2725
NOD/ShiLtJ f 0.625 0.2129 1.0431 0.2069
NOD/ShiLtJ m 0.5833 0.2458 1.0661 0.1006
NON/ShiLtJ f 0.4444 0.2007 0.8386 0.0503
NON/ShiLtJ m 0.1111 0.2007 0.5053 -0.2831
NZB/BlNJ f 0.9444 0.2007 1.3386 0.5503
NZB/BlNJ m 0.4444 0.2007 0.8386 0.0503
NZW/LacJ f 1.3125 0.2129 1.7306 0.8944
NZW/LacJ m 1.1111 0.2007 1.5053 0.7169
PERA/EiJ f 0.0625 0.2129 0.4806 -0.3556
PERA/EiJ m 0.0 0.3011 0.5913 -0.5913
P/J f 0.6667 0.2007 1.0608 0.2725
P/J m 0.7222 0.2007 1.1164 0.3281
PL/J f 0.5 0.1904 0.8739 0.1261
PL/J m 0.0 0.3477 0.6827 -0.6827
RBF/DnJ f 0.4444 0.2007 0.8386 0.0503
RBF/DnJ m 0.2222 0.2007 0.6164 -0.1719
RF/J f 0.5 0.1904 0.8739 0.1261
RF/J m 0.3 0.2693 0.8288 -0.2288
RIIIS/J f 0.95 0.1904 1.3239 0.5761
RIIIS/J m 0.9444 0.2007 1.3386 0.5503
SEA/GnJ f 1.1875 0.2129 1.6056 0.7694
SEA/GnJ m 0.85 0.1904 1.2239 0.4761
SJL/J f 0.1 0.1904 0.4739 -0.2739
SJL/J m 0.3333 0.2007 0.7275 -0.0608
SM/J f 0.0714 0.2276 0.5184 -0.3755
SM/J m 0.2 0.2693 0.7288 -0.3288
SPRET/EiJ f 0.4286 0.2276 0.8755 -0.0184
SPRET/EiJ m 0.2 0.2693 0.7288 -0.3288
SWR/J f 0.7 0.1904 1.0739 0.3261
SWR/J m 1.125 0.2129 1.5431 0.7069
WSB/EiJ f 0.5 0.2129 0.9181 0.0819
WSB/EiJ m 0.6667 0.2458 1.1494 0.1839


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.225 0.1346 0.4894 -0.0394
A/J both 0.825 0.1346 1.0894 0.5606
AKR/J both 0.6667 0.1419 0.9454 0.3879
BALB/cJ both 0.125 0.1346 0.3894 -0.1394
BPH/2J both 0.4694 0.1383 0.7411 0.1978
BPL/1J both 0.65 0.1346 0.9144 0.3856
BPN/3J both 0.4056 0.1383 0.6772 0.1339
BTBR T+ Itpr3tf/J both 1.5333 0.1982 1.9225 1.1441
C3H/HeJ both 0.5556 0.1679 0.8853 0.2258
C57BL/10J both 0.8 0.1346 1.0644 0.5356
C57BL/6J both 0.6167 0.1555 0.922 0.3113
C57BLKS/J both 0.4833 0.1823 0.8414 0.1253
C57BR/cdJ both 0.8083 0.1383 1.08 0.5367
C57L/J both 1.8 0.1346 2.0644 1.5356
C58/J both 1.25 0.1346 1.5144 0.9856
CAST/EiJ both 0.3333 0.1679 0.6631 0.0035
CBA/J both 0.8056 0.1383 1.0772 0.5339
CE/J both 0.3472 0.1587 0.6588 0.0356
CZECHII/EiJ both 0.6429 0.1609 0.9589 0.3268
DBA/1J both 0.4688 0.1428 0.7492 0.1883
DBA/2J both 0.0 0.1383 0.2717 -0.2717
FVB/NJ both 0.6389 0.2007 1.0331 0.2447
I/LnJ both 0.4722 0.1419 0.7509 0.1935
KK/HlJ both 0.2014 0.1463 0.4887 -0.0859
LP/J both 0.6389 0.1419 0.9176 0.3602
MOLF/EiJ both 0.6389 0.1419 0.9176 0.3602
NOD/ShiLtJ both 0.6042 0.1626 0.9235 0.2849
NON/ShiLtJ both 0.2778 0.1419 0.5565 -0.0009
NZB/BlNJ both 0.6944 0.1419 0.9732 0.4157
NZW/LacJ both 1.2118 0.1463 1.4991 0.9245
PERA/EiJ both 0.0313 0.1844 0.3933 -0.3308
P/J both 0.6944 0.1419 0.9732 0.4157
PL/J both 0.25 0.1982 0.6392 -0.1392
RBF/DnJ both 0.3333 0.1419 0.6121 0.0546
RF/J both 0.4 0.1649 0.7238 0.0762
RIIIS/J both 0.9472 0.1383 1.2189 0.6756
SEA/GnJ both 1.0187 0.1428 1.2992 0.7383
SJL/J both 0.2167 0.1383 0.4883 -0.055
SM/J both 0.1357 0.1763 0.4819 -0.2105
SPRET/EiJ both 0.3143 0.1763 0.6605 -0.0319
SWR/J both 0.9125 0.1428 1.193 0.632
WSB/EiJ both 0.5833 0.1626 0.9026 0.264




  GWAS USING LINEAR MIXED MODELS