Phenotype measure:   Paigen1   mucin

ID, description, units MPD:2909   mucin   gallbladder, mucin (score: 0-4)   [score]
high-fat diet study
Data set, strains Paigen1   inbred   43 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Paigen1 - gallbladder, mucin (score: 0-4)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains42 strains
Mean of the strain means1.44   score 1.53   score
Median of the strain means1.39   score 1.36   score
SD of the strain means± 0.542 ± 0.670
Coefficient of variation (CV)0.376 0.438
Min–max range of strain means0.500   –   2.67   score 0.333   –   3.00   score
Mean sample size per strain8.8   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.943 0.943 2.0306 0.1547
strain 41 190.2809 4.641 9.9942 < 0.0001
sex:strain 41 61.3664 1.4967 3.2232 < 0.0001
Residuals 621 288.3743 0.4644


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.75 0.791   10 0.25 1.05 -1.28
129S1/SvImJ m 0.8 0.258   10 0.0816 0.323 0.5, 1.0 -1.09
A/J f 1.4 0.516   10 0.163 0.369 1.0, 2.0 -0.08
A/J m 1.4 0.516   10 0.163 0.369 1.0, 2.0 -0.2
AKR/J f 1.39 0.741   9 0.247 0.533 0.5, 2.0 -0.1
AKR/J m 1.78 0.441   9 0.147 0.248 1.0, 2.0 0.37
BALB/cJ f 0.8 0.537   10 0.17 0.672 -1.19
BALB/cJ m 1.75 1.16   10 0.367 0.663 0.5, 4.0 0.33
BPH/2J f 1.75 0.979   10 0.31 0.559 0.5, 4.0 0.57
BPH/2J m 1.0 0.0   9 0.0 0.0 1.0, 1.0 -0.79
BPL/1J f 1.5 0.707   10 0.224 0.471 1.0, 3.0 0.11
BPL/1J m 1.2 0.422   10 0.133 0.351 1.0, 2.0 -0.49
BPN/3J f 0.9 0.459   10 0.145 0.511 0.5, 2.0 -1.0
BPN/3J m 1.17 0.5   9 0.167 0.429 0.5, 2.0 -0.54
BTBR T+ Itpr3tf/J f 0.5 0.0   3 0.0 0.0 0.5, 0.5 -1.74
BTBR T+ Itpr3tf/J m 1.2 0.422   10 0.133 0.351 1.0, 2.0 -0.49
C3H/HeJ f 1.39 0.782   9 0.261 0.563 0.5, 3.0 -0.1
C3H/HeJ m 2.6 0.894   5 0.4 0.344 2.0, 4.0 1.6
C57BL/10J f 1.6 0.843   10 0.267 0.527 1.0, 3.0 0.29
C57BL/10J m 2.9 0.994   10 0.314 0.343 1.0, 4.0 2.04
C57BL/6J f 1.9 0.738   10 0.233 0.388 1.0, 3.0 0.84
C57BL/6J m 1.58 0.665   6 0.271 0.42 0.5, 2.0 0.07
C57BLKS/J f 0.75 0.274   6 0.112 0.365 0.5, 1.0 -1.28
C57BLKS/J m 1.2 0.447   5 0.2 0.373 1.0, 2.0 -0.49
C57BR/cdJ f 1.56 1.01   9 0.338 0.652 1.0, 4.0 0.22
C57BR/cdJ m 0.9 0.459   10 0.145 0.511 0.5, 2.0 -0.94
C57L/J f 2.2 0.919   10 0.291 0.418 1.0, 4.0 1.4
C57L/J m 2.56 0.726   9 0.242 0.284 2.0, 4.0 1.54
C58/J f 2.3 1.06   10 0.335 0.461 1.0, 4.0 1.58
C58/J m 3.0 0.816   10 0.258 0.272 2.0, 4.0 2.19
CAST/EiJ f 1.0 0.612   5 0.274 0.612 0.5, 2.0 -0.82
CAST/EiJ m 2.11 1.27   9 0.423 0.601 0.86
CBA/J f 0.944 0.464   9 0.155 0.491 0.5, 2.0 -0.92
CBA/J m 1.0 0.577   10 0.183 0.577 0.5, 2.0 -0.79
CE/J f 2.67 0.866   9 0.289 0.325 2.0, 4.0 2.26
CE/J m 1.5 1.0   6 0.408 0.667 0.5, 3.0 -0.05
CZECHII/EiJ f 1.43 0.535   7 0.202 0.374 1.0, 2.0 -0.02
CZECHII/EiJ m 1.29 0.488   7 0.184 0.38 1.0, 2.0 -0.36
DBA/1J f 1.15 0.784   10 0.248 0.681 0.5, 3.0 -0.54
DBA/1J m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.79
DBA/2J f 0.8 0.258   10 0.0816 0.323 0.5, 1.0 -1.19
DBA/2J m 1.33 0.5   9 0.167 0.375 1.0, 2.0 -0.3
FVB/NJ f 0.889 0.22   9 0.0735 0.248 0.5, 1.0 -1.02
FVB/NJ m 1.33 0.577   3 0.333 0.433 1.0, 2.0 -0.3
I/LnJ f 1.72 0.565   9 0.188 0.328 0.5, 2.0 0.51
I/LnJ m 1.0 0.0   9 0.0 0.0 1.0, 1.0 -0.79
KK/HlJ f 1.06 0.417   8 0.148 0.393 0.5, 2.0 -0.71
KK/HlJ m 0.667 0.25   9 0.0833 0.375 0.5, 1.0 -1.29
LP/J f 1.22 0.441   9 0.147 0.361 1.0, 2.0 -0.41
LP/J m 1.67 0.707   9 0.236 0.424 1.0, 3.0 0.21
MOLF/EiJ f 1.5 1.06   9 0.354 0.707 0.5, 4.0 0.11
MOLF/EiJ m 1.33 0.707   9 0.236 0.53 1.0, 3.0 -0.3
NOD/ShiLtJ f 1.88 0.835   8 0.295 0.445 1.0, 3.0 0.81
NOD/ShiLtJ m 1.08 0.492   6 0.201 0.454 0.5, 2.0 -0.67
NON/ShiLtJ f 1.33 0.5   9 0.167 0.375 1.0, 2.0 -0.21
NON/ShiLtJ m 1.22 0.667   9 0.222 0.545 1.0, 3.0 -0.46
NZB/BlNJ f 1.78 0.441   9 0.147 0.248 1.0, 2.0 0.62
NZB/BlNJ m 1.56 1.01   9 0.338 0.652 1.0, 4.0 0.04
NZW/LacJ f 1.12 0.354   8 0.125 0.314 1.0, 2.0 -0.6
NZW/LacJ m 1.4 0.966   10 0.306 0.69 1.0, 4.0 -0.2
PERA/EiJ f 1.12 0.354   8 0.125 0.314 1.0, 2.0 -0.6
PERA/EiJ m 1.75 0.5   4 0.25 0.286 1.0, 2.0 0.33
P/J f 1.17 0.5   9 0.167 0.429 0.5, 2.0 -0.5
P/J m 1.89 1.27   9 0.423 0.672 1.0, 4.0 0.54
PL/J f 0.8 0.483   10 0.153 0.604 0.5, 2.0 -1.19
PL/J m 0.333 0.289   3 0.167 0.866 -1.79
RBF/DnJ f 1.17 0.661   9 0.22 0.567 0.5, 2.0 -0.5
RBF/DnJ m 0.722 0.264   9 0.0878 0.365 0.5, 1.0 -1.21
RF/J f 2.4 0.516   10 0.163 0.215 2.0, 3.0 1.77
RF/J m 1.2 0.447   5 0.2 0.373 1.0, 2.0 -0.49
RIIIS/J f 2.5 0.85   10 0.269 0.34 1.0, 4.0 1.95
RIIIS/J m 2.33 0.5   9 0.167 0.214 2.0, 3.0 1.19
SEA/GnJ f 1.5 0.535   8 0.189 0.356 1.0, 2.0 0.11
SEA/GnJ m 2.0 0.816   10 0.258 0.408 1.0, 3.0 0.7
SJL/J f 1.0 0.882   10 0.279 0.882 -0.82
SJL/J m 0.389 0.333   9 0.111 0.857 -1.7
SM/J f 1.86 0.69   7 0.261 0.372 1.0, 3.0 0.77
SM/J m 2.4 0.548   5 0.245 0.228 2.0, 3.0 1.3
SPRET/EiJ f 1.0 0.0   7 0.0 0.0 1.0, 1.0 -0.82
SPRET/EiJ m 1.4 0.548   5 0.245 0.391 1.0, 2.0 -0.2
SWR/J f 2.1 0.316   10 0.1 0.151 2.0, 3.0 1.21
SWR/J m 2.75 0.886   8 0.313 0.322 2.0, 4.0 1.82
WSB/EiJ f 2.25 0.886   8 0.313 0.394 1.0, 3.0 1.49
WSB/EiJ m 2.6 0.894   5 0.4 0.344 1.0, 3.0 1.6
YBR/EiJ f 2.0 0.0   3 0.0 0.0 2.0, 2.0 1.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.75 0.2155 1.1732 0.3268
129S1/SvImJ m 0.8 0.2155 1.2232 0.3768
A/J f 1.4 0.2155 1.8232 0.9768
A/J m 1.4 0.2155 1.8232 0.9768
AKR/J f 1.3889 0.2271 1.835 0.9428
AKR/J m 1.7778 0.2271 2.2239 1.3317
BALB/cJ f 0.8 0.2155 1.2232 0.3768
BALB/cJ m 1.75 0.2155 2.1732 1.3268
BPH/2J f 1.75 0.2155 2.1732 1.3268
BPH/2J m 1.0 0.2271 1.4461 0.5539
BPL/1J f 1.5 0.2155 1.9232 1.0768
BPL/1J m 1.2 0.2155 1.6232 0.7768
BPN/3J f 0.9 0.2155 1.3232 0.4768
BPN/3J m 1.1667 0.2271 1.6127 0.7206
BTBR T+ Itpr3tf/J f 0.5 0.3934 1.2726 0.0
BTBR T+ Itpr3tf/J m 1.2 0.2155 1.6232 0.7768
C3H/HeJ f 1.3889 0.2271 1.835 0.9428
C3H/HeJ m 2.6 0.3048 3.1985 2.0015
C57BL/10J f 1.6 0.2155 2.0232 1.1768
C57BL/10J m 2.9 0.2155 3.3232 2.4768
C57BL/6J f 1.9 0.2155 2.3232 1.4768
C57BL/6J m 1.5833 0.2782 2.1297 1.037
C57BLKS/J f 0.75 0.2782 1.2963 0.2037
C57BLKS/J m 1.2 0.3048 1.7985 0.6015
C57BR/cdJ f 1.5556 0.2271 2.0016 1.1095
C57BR/cdJ m 0.9 0.2155 1.3232 0.4768
C57L/J f 2.2 0.2155 2.6232 1.7768
C57L/J m 2.5556 0.2271 3.0016 2.1095
C58/J f 2.3 0.2155 2.7232 1.8768
C58/J m 3.0 0.2155 3.4232 2.5768
CAST/EiJ f 1.0 0.3048 1.5985 0.4015
CAST/EiJ m 2.1111 0.2271 2.5572 1.665
CBA/J f 0.9444 0.2271 1.3905 0.4984
CBA/J m 1.0 0.2155 1.4232 0.5768
CE/J f 2.6667 0.2271 3.1127 2.2206
CE/J m 1.5 0.2782 2.0463 0.9537
CZECHII/EiJ f 1.4286 0.2576 1.9344 0.9228
CZECHII/EiJ m 1.2857 0.2576 1.7915 0.7799
DBA/1J f 1.15 0.2155 1.5732 0.7268
DBA/1J m 1.0 0.2409 1.4731 0.5269
DBA/2J f 0.8 0.2155 1.2232 0.3768
DBA/2J m 1.3333 0.2271 1.7794 0.8873
FVB/NJ f 0.8889 0.2271 1.335 0.4428
FVB/NJ m 1.3333 0.3934 2.106 0.5607
I/LnJ f 1.7222 0.2271 2.1683 1.2761
I/LnJ m 1.0 0.2271 1.4461 0.5539
KK/HlJ f 1.0625 0.2409 1.5356 0.5894
KK/HlJ m 0.6667 0.2271 1.1127 0.2206
LP/J f 1.2222 0.2271 1.6683 0.7761
LP/J m 1.6667 0.2271 2.1127 1.2206
MOLF/EiJ f 1.5 0.2271 1.9461 1.0539
MOLF/EiJ m 1.3333 0.2271 1.7794 0.8873
NOD/ShiLtJ f 1.875 0.2409 2.3481 1.4019
NOD/ShiLtJ m 1.0833 0.2782 1.6297 0.537
NON/ShiLtJ f 1.3333 0.2271 1.7794 0.8873
NON/ShiLtJ m 1.2222 0.2271 1.6683 0.7761
NZB/BlNJ f 1.7778 0.2271 2.2239 1.3317
NZB/BlNJ m 1.5556 0.2271 2.0016 1.1095
NZW/LacJ f 1.125 0.2409 1.5981 0.6519
NZW/LacJ m 1.4 0.2155 1.8232 0.9768
PERA/EiJ f 1.125 0.2409 1.5981 0.6519
PERA/EiJ m 1.75 0.3407 2.4191 1.0809
P/J f 1.1667 0.2271 1.6127 0.7206
P/J m 1.8889 0.2271 2.335 1.4428
PL/J f 0.8 0.2155 1.2232 0.3768
PL/J m 0.3333 0.3934 1.106 0.0
RBF/DnJ f 1.1667 0.2271 1.6127 0.7206
RBF/DnJ m 0.7222 0.2271 1.1683 0.2761
RF/J f 2.4 0.2155 2.8232 1.9768
RF/J m 1.2 0.3048 1.7985 0.6015
RIIIS/J f 2.5 0.2155 2.9232 2.0768
RIIIS/J m 2.3333 0.2271 2.7794 1.8873
SEA/GnJ f 1.5 0.2409 1.9731 1.0269
SEA/GnJ m 2.0 0.2155 2.4232 1.5768
SJL/J f 1.0 0.2155 1.4232 0.5768
SJL/J m 0.3889 0.2271 0.835 0.0
SM/J f 1.8571 0.2576 2.3629 1.3513
SM/J m 2.4 0.3048 2.9985 1.8015
SPRET/EiJ f 1.0 0.2576 1.5058 0.4942
SPRET/EiJ m 1.4 0.3048 1.9985 0.8015
SWR/J f 2.1 0.2155 2.5232 1.6768
SWR/J m 2.75 0.2409 3.2231 2.2769
WSB/EiJ f 2.25 0.2409 2.7231 1.7769
WSB/EiJ m 2.6 0.3048 3.1985 2.0015


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.775 0.1524 1.0742 0.4758
A/J both 1.4 0.1524 1.6992 1.1008
AKR/J both 1.5833 0.1606 1.8988 1.2679
BALB/cJ both 1.275 0.1524 1.5742 0.9758
BPH/2J both 1.375 0.1566 1.6824 1.0676
BPL/1J both 1.35 0.1524 1.6492 1.0508
BPN/3J both 1.0333 0.1566 1.3408 0.7259
BTBR T+ Itpr3tf/J both 0.85 0.2243 1.2905 0.4095
C3H/HeJ both 1.9944 0.19 2.3677 1.6212
C57BL/10J both 2.25 0.1524 2.5492 1.9508
C57BL/6J both 1.7417 0.1759 2.0872 1.3961
C57BLKS/J both 0.975 0.2063 1.3802 0.5698
C57BR/cdJ both 1.2278 0.1566 1.5352 0.9203
C57L/J both 2.3778 0.1566 2.6852 2.0703
C58/J both 2.65 0.1524 2.9492 2.3508
CAST/EiJ both 1.5556 0.19 1.9288 1.1823
CBA/J both 0.9722 0.1566 1.2797 0.6648
CE/J both 2.0833 0.1796 2.436 1.7307
CZECHII/EiJ both 1.3571 0.1821 1.7148 0.9995
DBA/1J both 1.075 0.1616 1.3924 0.7576
DBA/2J both 1.0667 0.1566 1.3741 0.7592
FVB/NJ both 1.1111 0.2271 1.5572 0.665
I/LnJ both 1.3611 0.1606 1.6765 1.0457
KK/HlJ both 0.8646 0.1656 1.1897 0.5395
LP/J both 1.4444 0.1606 1.7599 1.129
MOLF/EiJ both 1.4167 0.1606 1.7321 1.1012
NOD/ShiLtJ both 1.4792 0.184 1.8405 1.1178
NON/ShiLtJ both 1.2778 0.1606 1.5932 0.9624
NZB/BlNJ both 1.6667 0.1606 1.9821 1.3512
NZW/LacJ both 1.2625 0.1616 1.5799 0.9451
PERA/EiJ both 1.4375 0.2086 1.8472 1.0278
P/J both 1.5278 0.1606 1.8432 1.2124
PL/J both 0.5667 0.2243 1.0071 0.1262
RBF/DnJ both 0.9444 0.1606 1.2599 0.629
RF/J both 1.8 0.1866 2.1665 1.4335
RIIIS/J both 2.4167 0.1566 2.7241 2.1092
SEA/GnJ both 1.75 0.1616 2.0674 1.4326
SJL/J both 0.6944 0.1566 1.0019 0.387
SM/J both 2.1286 0.1995 2.5204 1.7368
SPRET/EiJ both 1.2 0.1995 1.5918 0.8082
SWR/J both 2.425 0.1616 2.7424 2.1076
WSB/EiJ both 2.425 0.1942 2.8065 2.0435




  GWAS USING LINEAR MIXED MODELS