Phenotype measure:   Ackert1   BMC_M12

ID, description, units MPD:25017   BMC_M12   bone mineral content (BMC)   [g]  at age 12mo
Data set, strains Ackert1   inbred   30 strains     sex: both     age: 52wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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Ackert1 - bone mineral content (BMC) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains28 strains
Mean of the strain means0.552   g 0.553   g
Median of the strain means0.533   g 0.555   g
SD of the strain means± 0.119 ± 0.103
Coefficient of variation (CV)0.215 0.185
Min–max range of strain means0.384   –   0.834   g 0.393   –   0.791   g
Mean sample size per strain7.6   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.012 0.012 5.1458 0.0239
strain 26 3.8733 0.149 63.6536 < 0.0001
sex:strain 26 0.3271 0.0126 5.3762 < 0.0001
Residuals 345 0.8074 0.0023


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.587 0.0333   8 0.0118 0.0567 0.535, 0.637 0.3
129S1/SvImJ m 0.578 0.0578   8 0.0204 0.1 0.481, 0.67 0.24
A/J f 0.394 0.0587   8 0.0208 0.149 0.332, 0.516 -1.33
A/J m 0.393 0.0289   3 0.0167 0.0736 0.375, 0.426 -1.57
AKR/J f 0.683 0.0533   3 0.0308 0.0781 0.641, 0.743 1.1
BALB/cByJ f 0.533 0.0432   8 0.0153 0.081 0.472, 0.586 -0.16
BALB/cByJ m 0.543 0.028   7 0.0106 0.0515 0.508, 0.592 -0.1
BTBR T+ Itpr3tf/J f 0.681 0.0649   7 0.0245 0.0953 0.563, 0.746 1.09
BTBR T+ Itpr3tf/J m 0.678 0.028   8 0.00991 0.0414 0.619, 0.707 1.21
BUB/BnJ f 0.5 0.0589   7 0.0223 0.118 0.399, 0.566 -0.44
BUB/BnJ m 0.585 0.0688   8 0.0243 0.118 0.508, 0.7 0.31
C3H/HeJ f 0.638 0.0645   7 0.0244 0.101 0.54, 0.715 0.73
C3H/HeJ m 0.748 0.0323   7 0.0122 0.0432 0.706, 0.801 1.9
C57BL/10J f 0.393 0.0646   8 0.0228 0.164 0.273, 0.466 -1.34
C57BL/10J m 0.43 0.0289   6 0.0118 0.0671 0.384, 0.459 -1.2
C57BL/6J f 0.436 0.0308   8 0.0109 0.0708 0.384, 0.477 -0.97
C57BL/6J m 0.515 0.0405   8 0.0143 0.0788 0.459, 0.569 -0.38
C57BLKS/J f 0.384 0.0305   8 0.0108 0.0796 0.342, 0.433 -1.41
C57BLKS/J m 0.464 0.0191   8 0.00676 0.0412 0.424, 0.49 -0.87
C57BR/cdJ f 0.663 0.033   7 0.0125 0.0498 0.615, 0.697 0.94
C57BR/cdJ m 0.548 0.0275   3 0.0159 0.0502 0.52, 0.575 -0.05
C57L/J f 0.612 0.0843   8 0.0298 0.138 0.494, 0.719 0.51
C57L/J m 0.567 0.0997   8 0.0353 0.176 0.467, 0.743 0.13
CBA/J f 0.577 0.0891   8 0.0315 0.154 0.483, 0.777 0.21
CBA/J m 0.608 0.0452   8 0.016 0.0744 0.565, 0.699 0.53
DBA/2J f 0.403 0.0192   8 0.00677 0.0476 0.361, 0.425 -1.25
DBA/2J m 0.539 0.0478   9 0.0159 0.0887 0.469, 0.587 -0.14
FVB/NJ f 0.48 0.0263   7 0.00996 0.0549 0.443, 0.525 -0.6
FVB/NJ m 0.543 0.0383   9 0.0128 0.0705 0.474, 0.59 -0.1
KK/HlJ f 0.679 0.0444   8 0.0157 0.0654 0.599, 0.725 1.07
KK/HlJ m 0.589 0.0184   9 0.00615 0.0313 0.555, 0.627 0.35
LP/J f 0.576 0.0707   8 0.025 0.123 0.486, 0.718 0.2
LP/J m 0.579 0.0431   10 0.0136 0.0744 0.495, 0.629 0.25
MRL/MpJ f 0.834 0.05   5 0.0224 0.06 0.779, 0.911 2.38
MRL/MpJ m 0.791 0.0195   3 0.0113 0.0246 0.772, 0.811 2.32
NOD.B10Sn-H2b/J f 0.698 0.0362   8 0.0128 0.0519 0.652, 0.753 1.23
NOD.B10Sn-H2b/J m 0.664 0.0261   8 0.00922 0.0393 0.614, 0.693 1.08
NON/ShiLtJ f 0.631 0.0371   9 0.0124 0.0588 0.569, 0.69 0.67
NON/ShiLtJ m 0.61 0.0565   8 0.02 0.0926 0.53, 0.683 0.55
NZO/HlLtJ f 0.726 0.0563   7 0.0213 0.0775 0.655, 0.796 1.47
NZO/HlLtJ m 0.69 0.106   4 0.0532 0.154 0.579, 0.835 1.33
NZW/LacJ f 0.604 0.0632   9 0.0211 0.105 0.505, 0.711 0.44
NZW/LacJ m 0.609 0.0279   8 0.00988 0.0459 0.575, 0.647 0.54
P/J m 0.409 0.0879   3 0.0508 0.215 0.337, 0.507 -1.41
PL/J f 0.43 0.0246   4 0.0123 0.0572 0.402, 0.46 -1.03
PL/J m 0.421 0.0248   8 0.00878 0.059 0.396, 0.474 -1.29
PWD/PhJ f 0.469 0.0257   9 0.00858 0.0549 0.43, 0.501 -0.7
PWD/PhJ m 0.402 0.018   9 0.00601 0.0449 0.378, 0.441 -1.48
RIIIS/J f 0.48 0.02   8 0.00707 0.0417 0.446, 0.512 -0.6
RIIIS/J m 0.494 0.0623   8 0.022 0.126 0.427, 0.626 -0.58
SJL/J f 0.516 0.0296   8 0.0105 0.0573 0.495, 0.575 -0.3
SM/J f 0.407 0.0246   8 0.00871 0.0605 0.375, 0.436 -1.22
SM/J m 0.457 0.0145   8 0.00513 0.0317 0.441, 0.486 -0.94
SWR/J f 0.518 0.0224   8 0.00792 0.0432 0.482, 0.545 -0.28
SWR/J m 0.562 0.0289   7 0.0109 0.0514 0.529, 0.61 0.08
WSB/EiJ f 0.47 0.0828   7 0.0313 0.176 0.35, 0.599 -0.69
WSB/EiJ m 0.482 0.0449   4 0.0224 0.0932 0.443, 0.544 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.5871 0.0171 0.6208 0.5535
129S1/SvImJ m 0.5784 0.0171 0.612 0.5447
A/J f 0.3944 0.0171 0.428 0.3607
A/J m 0.3927 0.0279 0.4476 0.3377
BALB/cByJ f 0.5333 0.0171 0.5669 0.4996
BALB/cByJ m 0.5429 0.0183 0.5788 0.5069
BTBR T+ Itpr3tf/J f 0.6811 0.0183 0.7171 0.6452
BTBR T+ Itpr3tf/J m 0.6778 0.0171 0.7114 0.6441
BUB/BnJ f 0.5001 0.0183 0.5361 0.4642
BUB/BnJ m 0.5854 0.0171 0.619 0.5517
C3H/HeJ f 0.6377 0.0183 0.6737 0.6018
C3H/HeJ m 0.748 0.0183 0.784 0.712
C57BL/10J f 0.3932 0.0171 0.4269 0.3596
C57BL/10J m 0.4303 0.0197 0.4692 0.3915
C57BL/6J f 0.4356 0.0171 0.4693 0.402
C57BL/6J m 0.5146 0.0171 0.5483 0.481
C57BLKS/J f 0.3836 0.0171 0.4173 0.35
C57BLKS/J m 0.464 0.0171 0.4976 0.4304
C57BR/cdJ f 0.6631 0.0183 0.6991 0.6272
C57BR/cdJ m 0.548 0.0279 0.6029 0.4931
C57L/J f 0.6121 0.0171 0.6458 0.5785
C57L/J m 0.5669 0.0171 0.6005 0.5332
CBA/J f 0.5766 0.0171 0.6103 0.543
CBA/J m 0.608 0.0171 0.6416 0.5744
DBA/2J f 0.4027 0.0171 0.4364 0.3691
DBA/2J m 0.539 0.0161 0.5707 0.5073
FVB/NJ f 0.4799 0.0183 0.5158 0.4439
FVB/NJ m 0.5432 0.0161 0.5749 0.5115
KK/HlJ f 0.6786 0.0171 0.7123 0.645
KK/HlJ m 0.5894 0.0161 0.6212 0.5577
LP/J f 0.576 0.0171 0.6096 0.5424
LP/J m 0.5791 0.0153 0.6092 0.549
MRL/MpJ f 0.8344 0.0216 0.877 0.7918
MRL/MpJ m 0.7913 0.0279 0.8463 0.7364
NOD.B10Sn-H2b/J f 0.6984 0.0171 0.732 0.6647
NOD.B10Sn-H2b/J m 0.6645 0.0171 0.6981 0.6309
NON/ShiLtJ f 0.6311 0.0161 0.6628 0.5994
NON/ShiLtJ m 0.6102 0.0171 0.6439 0.5766
NZO/HlLtJ f 0.7263 0.0183 0.7622 0.6903
NZO/HlLtJ m 0.6895 0.0242 0.7371 0.6419
NZW/LacJ f 0.604 0.0161 0.6357 0.5723
NZW/LacJ m 0.6091 0.0171 0.6428 0.5755
PL/J f 0.43 0.0242 0.4776 0.3824
PL/J m 0.4209 0.0171 0.4545 0.3872
PWD/PhJ f 0.469 0.0161 0.5007 0.4373
PWD/PhJ m 0.4018 0.0161 0.4335 0.3701
RIIIS/J f 0.4797 0.0171 0.5134 0.4461
RIIIS/J m 0.4936 0.0171 0.5273 0.46
SM/J f 0.4074 0.0171 0.441 0.3737
SM/J m 0.4573 0.0171 0.4909 0.4236
SWR/J f 0.5184 0.0171 0.552 0.4847
SWR/J m 0.5617 0.0183 0.5977 0.5258
WSB/EiJ f 0.4696 0.0183 0.5055 0.4336
WSB/EiJ m 0.4818 0.0242 0.5293 0.4342


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.5828 0.0121 0.6065 0.559
A/J both 0.3935 0.0164 0.4257 0.3613
BALB/cByJ both 0.5381 0.0125 0.5627 0.5134
BTBR T+ Itpr3tf/J both 0.6794 0.0125 0.7041 0.6548
BUB/BnJ both 0.5428 0.0125 0.5674 0.5181
C3H/HeJ both 0.6929 0.0129 0.7183 0.6674
C57BL/10J both 0.4118 0.0131 0.4375 0.3861
C57BL/6J both 0.4751 0.0121 0.4989 0.4513
C57BLKS/J both 0.4238 0.0121 0.4476 0.4
C57BR/cdJ both 0.6056 0.0167 0.6384 0.5727
C57L/J both 0.5895 0.0121 0.6133 0.5657
CBA/J both 0.5923 0.0121 0.6161 0.5685
DBA/2J both 0.4709 0.0118 0.494 0.4478
FVB/NJ both 0.5115 0.0122 0.5355 0.4876
KK/HlJ both 0.634 0.0118 0.6572 0.6109
LP/J both 0.5776 0.0115 0.6001 0.555
MRL/MpJ both 0.8129 0.0177 0.8476 0.7781
NOD.B10Sn-H2b/J both 0.6814 0.0121 0.7052 0.6576
NON/ShiLtJ both 0.6207 0.0118 0.6438 0.5976
NZO/HlLtJ both 0.7079 0.0152 0.7377 0.6781
NZW/LacJ both 0.6066 0.0118 0.6297 0.5834
PL/J both 0.4254 0.0148 0.4546 0.3963
PWD/PhJ both 0.4354 0.0114 0.4578 0.413
RIIIS/J both 0.4867 0.0121 0.5105 0.4629
SM/J both 0.4323 0.0121 0.4561 0.4085
SWR/J both 0.54 0.0125 0.5647 0.5154
WSB/EiJ both 0.4757 0.0152 0.5055 0.4458




  GWAS USING LINEAR MIXED MODELS