Ackert1: Aging study: Bone mineral density and body composition of 32 inbred strains of mice (2008)

Ackert-Bicknell C, Beamer WG, Rosen CJ, Sundberg JP   With: Juan R, Godfrey D, Coombs HF

       
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Participants Cheryl Ackert-Bicknell       The Jackson Laboratory Bar Harbor, ME
Wesley G Beamer       The Jackson Laboratory Bar Harbor, ME
Clifford J Rosen       The Jackson Laboratory Bar Harbor, ME
John P Sundberg       The Jackson Laboratory Bar Harbor, ME
With: Juan R, Godfrey D, Coombs HF
ContactCheryl Ackert-Bicknell     cheryl.ackertb@jax.org     Lab web site
AffiliationJAX Nathan Shock Aging Center
AcknowledgementsFunding provided by NIH AG025707 (NIA Nathan Shock Center for Aging Research); The Ellison Medical Foundation
Project type Phenotype strain survey data set
MPD identifiersAckert1     MPD:250
Data changelog 1 update/correction.       Initial release date: 03/2011.
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Animals were assessed in a cross-sectional study using densitometer dual energy X-ray absorptiometry (DXA) system. Note: Phenotyping and data collection were performed by two technical teams; one group collected 6 mo data while the other group collected 12 and 20 mo data.

Summary of procedures that were conducted
• body size and weight Body weight, body length, body mass index. Aging study, 6mo, 12mo, 20mo.
• DXA Body mass, fat mass, lean mass, bone mineral density and content, body area, bone area. Aging study, 6mo, 12mo, 20mo.
Mice: inbred   32 strains   ♀♂   age 26, 52, 87 wks   3 cohorts

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Ackert1 25001 body size and weight (none) body length (tip of nose to base of tail)   [cm]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25006 body size and weight (none) body weight   [g]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25011 DXA (none) bone mineral density (BMD)   [g/cm2]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25016 DXA (none) bone mineral content (BMC)   [g]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25021 DXA (none) whole body bone area, head excluded   [cm2]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25026 DXA (none) total body area, head excluded   [cm2]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25031 body size and weight (none) body mass index (BMI)   [kg/m2]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25036 DXA (none) percent fat, head excluded   [%]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25041 DXA (none) total tissue mass, head excluded   [g]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25046 DXA (none) weight of lean tissue mass, head excluded   [g]     6mo    12mo    20mo inbred 31 both N=7
    Ackert1 25051 DXA (none) weight of fat portion of body mass, head excluded   [g]     6mo    12mo    20mo inbred 31 both N=7
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