Project measure / variable:   Xing1   RR_M12

ID, description, units MPD:24917   RR_M12   interval RR   [ms]  at age 12mo  
Data set, strains Xing1   inbred   28 strains     sex: both     age: 52wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Xing1 - interval RR at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains27 strains
Mean of the strain means84.2   ms 82.4   ms
Median of the strain means84.7   ms 81.8   ms
SD of the strain means± 3.88 ± 3.88
Coefficient of variation (CV)0.0461 0.0472
Min–max range of strain means77.4   –   92.4   ms 75.6   –   90.8   ms
Mean sample size per strain7.5   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 217.5158 217.5158 7.2453 0.0075
strain 25 3844.8997 153.796 5.1228 < 0.0001
sex:strain 25 1501.9987 60.0799 2.0012 0.0035
Residuals 338 10147.3004 30.0216


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 87.2 3.21   8 1.13 0.0368 80.3, 90.6 0.77
129S1/SvImJ m 82.4 3.99   8 1.41 0.0484 78.1, 89.3 0.01
A/J f 84.3 5.99   7 2.26 0.071 77.7, 95.5 0.02
A/J m 88.1 8.45   7 3.19 0.0959 78.8, 98.3 1.48
AKR/J f 90.8 28.9   4 14.4 0.318 74.6, 134.0 1.7
AKR/J m 75.6 1.88   5 0.843 0.0249 74.0, 78.6 -1.74
BALB/cByJ f 84.7 4.72   6 1.93 0.0557 78.0, 90.1 0.13
BALB/cByJ m 89.6 8.34   8 2.95 0.0931 84.1, 110.0 1.86
BTBR T+ Itpr3tf/J f 80.2 3.98   8 1.41 0.0496 73.3, 86.9 -1.03
BTBR T+ Itpr3tf/J m 80.5 3.43   8 1.21 0.0426 76.7, 87.3 -0.48
BUB/BnJ f 78.7 2.76   7 1.04 0.035 75.8, 83.7 -1.42
BUB/BnJ m 77.1 2.4   8 0.85 0.0312 74.3, 80.7 -1.35
C3H/HeJ f 77.4 2.51   8 0.887 0.0324 75.1, 83.1 -1.76
C3H/HeJ m 76.3 4.26   8 1.51 0.0558 71.7, 83.0 -1.56
C57BL/10J f 85.5 3.95   8 1.4 0.0462 80.6, 92.8 0.33
C57BL/10J m 81.9 3.29   8 1.16 0.0401 77.9, 87.3 -0.12
C57BL/6J f 82.6 2.83   7 1.07 0.0343 78.8, 86.8 -0.41
C57BL/6J m 81.0 2.1   8 0.741 0.0259 78.3, 84.4 -0.35
C57BLKS/J f 84.6 3.13   8 1.11 0.037 80.8, 89.0 0.1
C57BLKS/J m 81.8 4.81   8 1.7 0.0588 76.3, 92.2 -0.14
C57BR/cdJ f 81.5 3.18   6 1.3 0.039 78.7, 85.8 -0.7
C57BR/cdJ m 81.0 1.22   8 0.433 0.0151 78.7, 82.4 -0.35
C57L/J f 87.6 2.9   7 1.1 0.0331 82.1, 90.8 0.87
C57L/J m 84.5 4.02   8 1.42 0.0476 77.6, 91.8 0.55
CBA/J f 83.9 5.19   8 1.84 0.0619 78.4, 92.0 -0.08
CBA/J m 79.9 10.2   8 3.59 0.127 58.9, 92.2 -0.63
DBA/2J f 85.7 2.51   7 0.947 0.0293 83.1, 89.0 0.38
DBA/2J m 83.0 5.71   8 2.02 0.0688 78.0, 94.7 0.16
FVB/NJ f 85.6 7.75   8 2.74 0.0905 76.3, 98.9 0.36
FVB/NJ m 81.8 6.31   8 2.23 0.0771 74.5, 91.4 -0.14
KK/HlJ f 83.6 1.91   8 0.675 0.0228 80.2, 85.3 -0.16
KK/HlJ m 80.6 1.83   9 0.609 0.0226 78.5, 83.8 -0.45
LP/J f 79.8 3.67   7 1.39 0.0459 75.7, 84.9 -1.14
LP/J m 81.4 5.02   8 1.77 0.0616 77.2, 90.6 -0.25
MRL/MpJ f 85.8 2.76   7 1.04 0.0322 82.3, 90.5 0.41
MRL/MpJ m 84.2 7.21   6 2.94 0.0857 73.6, 92.9 0.47
NOD.B10Sn-H2b/J f 77.5 2.55   10 0.808 0.033 74.2, 81.5 -1.73
NOD.B10Sn-H2b/J m 76.6 3.07   8 1.08 0.04 72.5, 80.7 -1.48
NON/ShiLtJ f 86.3 3.37   7 1.27 0.039 79.7, 90.0 0.54
NON/ShiLtJ m 87.1 3.8   8 1.34 0.0436 80.8, 92.6 1.22
NZO/HlLtJ f 84.7 5.9   9 1.97 0.0696 76.9, 95.9 0.13
NZO/HlLtJ m 88.1 5.71   5 2.55 0.0648 81.5, 96.8 1.48
NZW/LacJ f 87.2 8.38   8 2.96 0.0961 79.2, 106.0 0.77
NZW/LacJ m 90.8 5.73   7 2.17 0.0632 84.4, 102.0 2.17
P/J m 81.7 4.07   6 1.66 0.0498 78.1, 87.8 -0.17
PL/J f 86.0 4.75   8 1.68 0.0552 78.3, 90.9 0.46
PL/J m 84.2 3.56   7 1.35 0.0423 80.2, 88.5 0.47
RIIIS/J f 92.4 10.0   7 3.79 0.108 78.2, 110.0 2.11
RIIIS/J m 80.9 1.76   8 0.623 0.0218 78.1, 83.2 -0.38
SJL/J f 89.9 10.7   8 3.77 0.119 79.6, 112.0 1.47
SM/J f 79.9 3.7   7 1.4 0.0463 75.8, 86.3 -1.11
SM/J m 80.4 2.9   8 1.02 0.036 76.7, 86.7 -0.5
SWR/J f 80.2 2.74   8 0.969 0.0342 77.7, 86.6 -1.03
SWR/J m 83.2 4.18   7 1.58 0.0502 79.2, 90.6 0.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 87.1625 1.9372 90.973 83.352
129S1/SvImJ m 82.3625 1.9372 86.173 78.552
A/J f 84.3429 2.0709 88.4164 80.2693
A/J m 88.1 2.0709 92.1736 84.0264
AKR/J f 90.85 2.7396 96.2388 85.4612
AKR/J m 75.62 2.4504 80.4399 70.8001
BALB/cByJ f 84.7333 2.2369 89.1333 80.3334
BALB/cByJ m 89.6375 1.9372 93.448 85.827
BTBR T+ Itpr3tf/J f 80.2 1.9372 84.0105 76.3895
BTBR T+ Itpr3tf/J m 80.55 1.9372 84.3605 76.7395
BUB/BnJ f 78.7429 2.0709 82.8164 74.6693
BUB/BnJ m 77.125 1.9372 80.9355 73.3145
C3H/HeJ f 77.375 1.9372 81.1855 73.5645
C3H/HeJ m 76.325 1.9372 80.1355 72.5145
C57BL/10J f 85.5375 1.9372 89.348 81.727
C57BL/10J m 81.95 1.9372 85.7605 78.1395
C57BL/6J f 82.5857 2.0709 86.6593 78.5122
C57BL/6J m 81.0125 1.9372 84.823 77.202
C57BLKS/J f 84.6125 1.9372 88.423 80.802
C57BLKS/J m 81.8375 1.9372 85.648 78.027
C57BR/cdJ f 81.5333 2.2369 85.9333 77.1334
C57BR/cdJ m 80.9875 1.9372 84.798 77.177
C57L/J f 87.6286 2.0709 91.7021 83.555
C57L/J m 84.4625 1.9372 88.273 80.652
CBA/J f 83.85 1.9372 87.6605 80.0395
CBA/J m 79.9375 1.9372 83.748 76.127
DBA/2J f 85.6571 2.0709 89.7307 81.5836
DBA/2J m 83.0125 1.9372 86.823 79.202
FVB/NJ f 85.6125 1.9372 89.423 81.802
FVB/NJ m 81.775 1.9372 85.5855 77.9645
KK/HlJ f 83.575 1.9372 87.3855 79.7645
KK/HlJ m 80.6111 1.8264 84.2037 77.0186
LP/J f 79.8 2.0709 83.8736 75.7264
LP/J m 81.4 1.9372 85.2105 77.5895
MRL/MpJ f 85.7714 2.0709 89.845 81.6979
MRL/MpJ m 84.1833 2.2369 88.5833 79.7834
NOD.B10Sn-H2b/J f 77.53 1.7327 80.9382 74.1218
NOD.B10Sn-H2b/J m 76.6375 1.9372 80.448 72.827
NON/ShiLtJ f 86.3143 2.0709 90.3878 82.2407
NON/ShiLtJ m 87.125 1.9372 90.9355 83.3145
NZO/HlLtJ f 84.6889 1.8264 88.2814 81.0963
NZO/HlLtJ m 88.06 2.4504 92.8799 83.2401
NZW/LacJ f 87.2375 1.9372 91.048 83.427
NZW/LacJ m 90.7571 2.0709 94.8307 86.6836
PL/J f 85.9875 1.9372 89.798 82.177
PL/J m 84.2429 2.0709 88.3164 80.1693
RIIIS/J f 92.3857 2.0709 96.4593 88.3122
RIIIS/J m 80.8875 1.9372 84.698 77.077
SM/J f 79.9143 2.0709 83.9878 75.8407
SM/J m 80.3625 1.9372 84.173 76.552
SWR/J f 80.225 1.9372 84.0355 76.4145
SWR/J m 83.2286 2.0709 87.3021 79.155


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 84.7625 1.3698 87.4569 82.0681
A/J both 86.2214 1.4644 89.1019 83.341
AKR/J both 83.235 1.8378 86.8499 79.6201
BALB/cByJ both 87.1854 1.4796 90.0957 84.2751
BTBR T+ Itpr3tf/J both 80.375 1.3698 83.0694 77.6806
BUB/BnJ both 77.9339 1.4179 80.7229 75.145
C3H/HeJ both 76.85 1.3698 79.5444 74.1556
C57BL/10J both 83.7437 1.3698 86.4382 81.0493
C57BL/6J both 81.7991 1.4179 84.5881 79.0101
C57BLKS/J both 83.225 1.3698 85.9194 80.5306
C57BR/cdJ both 81.2604 1.4796 84.1707 78.3501
C57L/J both 86.0455 1.4179 88.8345 83.2566
CBA/J both 81.8937 1.3698 84.5882 79.1993
DBA/2J both 84.3348 1.4179 87.1238 81.5458
FVB/NJ both 83.6937 1.3698 86.3882 80.9993
KK/HlJ both 82.0931 1.3312 84.7115 79.4746
LP/J both 80.6 1.4179 83.389 77.811
MRL/MpJ both 84.9774 1.5242 87.9754 81.9793
NOD.B10Sn-H2b/J both 77.0837 1.2995 79.6399 74.5276
NON/ShiLtJ both 86.7196 1.4179 89.5086 83.9307
NZO/HlLtJ both 86.3744 1.5281 89.3802 83.3687
NZW/LacJ both 88.9973 1.4179 91.7863 86.2083
PL/J both 85.1152 1.4179 87.9042 82.3262
RIIIS/J both 86.6366 1.4179 89.4256 83.8476
SM/J both 80.1384 1.4179 82.9274 77.3494
SWR/J both 81.7268 1.4179 84.5158 78.9378




  GWAS USING LINEAR MIXED MODELS