Phenotype measure:   Yuan3   HDL_M12

ID, description, units MPD:24472   HDL_M12   HDL cholesterol (plasma HDL)   [mg/dL]  at age 12mo
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - HDL cholesterol (plasma HDL) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means79.8   mg/dL 102   mg/dL
Median of the strain means78.9   mg/dL 94.2   mg/dL
SD of the strain means± 28.9 ± 29.0
Coefficient of variation (CV)0.362 0.284
Min–max range of strain means41.2   –   181   mg/dL 63.7   –   186   mg/dL
Mean sample size per strain6.6   mice 6.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 39480.9025 39480.9025 223.7618 < 0.0001
strain 23 269671.4211 11724.8444 66.4517 < 0.0001
sex:strain 23 16904.2242 734.9663 4.1655 < 0.0001
Residuals 300 52932.5007 176.4417


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 97.9 7.66   8 2.71 0.0783 89.9, 109.0 0.63
129S1/SvImJ m 123.0 10.0   8 3.55 0.0814 107.0, 136.0 0.71
A/J f 62.1 4.43   7 1.67 0.0714 54.5, 67.7 -0.61
A/J m 63.7 9.67   8 3.42 0.152 48.1, 73.8 -1.33
AKR/J m 67.0 16.4   4 8.18 0.244 49.6, 88.0 -1.22
BALB/cByJ f 79.5 0.0   1   0.0 0.0 79.5, 79.5 -0.01
BALB/cByJ m 92.3 5.14   8 1.82 0.0558 82.6, 99.2 -0.35
BTBR T+ Itpr3tf/J f 88.7 12.2   8 4.3 0.137 70.9, 103.0 0.31
BTBR T+ Itpr3tf/J m 102.0 21.6   7 8.18 0.212 72.3, 129.0 -0.01
BUB/BnJ f 48.1 18.2   6 7.44 0.379 23.6, 80.1 -1.1
BUB/BnJ m 79.0 15.2   9 5.06 0.192 58.9, 111.0 -0.8
C3H/HeJ f 96.0 0.0   1   0.0 0.0 96.0, 96.0 0.56
C3H/HeJ m 102.0 10.8   7 4.09 0.106 87.2, 114.0 -0.01
C57BL/10J f 51.2 7.65   8 2.7 0.149 43.2, 62.1 -0.99
C57BL/10J m 71.5 11.4   7 4.32 0.16 50.1, 87.6 -1.06
C57BL/6J f 57.8 7.21   8 2.55 0.125 48.0, 65.4 -0.76
C57BL/6J m 93.3 9.24   8 3.27 0.099 78.6, 106.0 -0.31
C57BLKS/J f 50.6 4.45   8 1.57 0.088 46.3, 59.3 -1.01
C57BLKS/J m 65.6 5.73   6 2.34 0.0874 58.6, 75.6 -1.27
C57BR/cdJ f 82.5 10.2   8 3.6 0.123 73.4, 100.0 0.1
C57BR/cdJ m 93.0 16.6   3 9.61 0.179 74.0, 105.0 -0.32
C57L/J f 71.3 15.8   7 5.99 0.222 53.1, 99.0 -0.29
C57L/J m 94.3 23.2   8 8.22 0.247 68.8, 135.0 -0.28
CAST/EiJ f 48.2 10.3   6 4.22 0.215 38.0, 66.8 -1.09
CBA/J f 74.0 15.4   8 5.44 0.208 39.4, 89.6 -0.2
CBA/J m 96.5 13.0   8 4.6 0.135 80.8, 120.0 -0.2
DBA/2J f 41.8 7.19   6 2.94 0.172 32.9, 49.8 -1.31
DBA/2J m 81.6 5.51   7 2.08 0.0675 72.9, 88.9 -0.71
FVB/NJ f 111.0 9.13   8 3.23 0.0825 98.7, 122.0 1.08
FVB/NJ m 133.0 13.1   8 4.64 0.0988 114.0, 148.0 1.06
KK/HlJ f 100.0 22.5   12 6.49 0.224 71.2, 143.0 0.7
KK/HlJ m 143.0 14.4   8 5.11 0.101 114.0, 164.0 1.4
LP/J f 88.7 8.68   7 3.28 0.0978 74.9, 97.3 0.31
LP/J m 106.0 6.74   8 2.38 0.0637 98.0, 114.0 0.13
MRL/MpJ f 89.6 12.1   8 4.27 0.135 74.5, 110.0 0.34
MRL/MpJ m 94.2 19.8   6 8.1 0.211 60.4, 113.0 -0.28
NOD.B10Sn-H2b/J f 72.3 6.37   7 2.41 0.088 65.2, 83.0 -0.26
NOD.B10Sn-H2b/J m 109.0 7.83   8 2.77 0.0715 96.8, 117.0 0.23
NON/ShiLtJ f 78.3 18.7   7 7.05 0.238 50.5, 102.0 -0.05
NON/ShiLtJ m 120.0 0.0   1   0.0 0.0 120.0, 120.0 0.61
NZO/HlLtJ f 181.0 12.5   7 4.73 0.0693 168.0, 202.0 3.51
NZO/HlLtJ m 186.0 28.2   4 14.1 0.151 153.0, 213.0 2.88
NZW/LacJ f 126.0 7.17   8 2.54 0.0567 118.0, 139.0 1.6
NZW/LacJ m 148.0 16.2   8 5.74 0.11 116.0, 165.0 1.57
P/J f 103.0 14.2   6 5.78 0.137 80.9, 115.0 0.8
P/J m 118.0 18.9   7 7.14 0.16 96.0, 144.0 0.54
PL/J f 87.0 26.3   7 9.94 0.303 58.8, 136.0 0.25
PL/J m 121.0 10.5   6 4.29 0.0872 102.0, 131.0 0.64
PWD/PhJ f 79.9 4.32   6 1.76 0.0541 73.1, 83.9 0.01
PWD/PhJ m 87.0 22.0   4 11.0 0.253 55.6, 107.0 -0.53
RIIIS/J f 59.9 5.76   5 2.58 0.0961 53.9, 67.9 -0.69
RIIIS/J m 74.4 0.0   1   0.0 0.0 74.4, 74.4 -0.96
SJL/J f 41.2 8.7   5 3.89 0.211 34.0, 52.2 -1.33
SJL/J m 83.0 8.31   9 2.77 0.1 68.5, 97.7 -0.67
SM/J f 77.8 5.91   7 2.23 0.0759 66.3, 84.1 -0.07
SM/J m 91.0 12.3   7 4.66 0.135 75.1, 108.0 -0.39
SWR/J f 51.8 0.0   1   0.0 0.0 51.8, 51.8 -0.97
SWR/J m 77.1 3.66   3 2.11 0.0475 74.1, 81.2 -0.87
WSB/EiJ f 95.3 9.69   8 3.42 0.102 82.3, 113.0 0.54
WSB/EiJ m 155.0 9.11   8 3.22 0.0589 138.0, 164.0 1.81


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 97.9375 4.6963 107.1794 88.6956
129S1/SvImJ m 123.375 4.6963 132.6169 114.1331
A/J f 62.1 5.0206 71.98 52.22
A/J m 63.7 4.6963 72.9419 54.4581
BTBR T+ Itpr3tf/J f 88.6625 4.6963 97.9044 79.4206
BTBR T+ Itpr3tf/J m 102.1 5.0206 111.98 92.22
BUB/BnJ f 48.1167 5.4228 58.7882 37.4451
BUB/BnJ m 78.9556 4.4277 87.6689 70.2422
C57BL/10J f 51.175 4.6963 60.4169 41.9331
C57BL/10J m 71.5 5.0206 81.38 61.62
C57BL/6J f 57.8125 4.6963 67.0544 48.5706
C57BL/6J m 93.325 4.6963 102.5669 84.0831
C57BLKS/J f 50.6125 4.6963 59.8544 41.3706
C57BLKS/J m 65.6167 5.4228 76.2882 54.9451
C57BR/cdJ f 82.4625 4.6963 91.7044 73.2206
C57BR/cdJ m 93.0 7.669 108.0919 77.9081
C57L/J f 71.2714 5.0206 81.1514 61.3915
C57L/J m 94.2625 4.6963 103.5044 85.0206
CBA/J f 73.9625 4.6963 83.2044 64.7206
CBA/J m 96.525 4.6963 105.7669 87.2831
DBA/2J f 41.85 5.4228 52.5216 31.1784
DBA/2J m 81.6429 5.0206 91.5228 71.7629
FVB/NJ f 110.6875 4.6963 119.9294 101.4456
FVB/NJ m 132.75 4.6963 141.9919 123.5081
KK/HlJ f 100.325 3.8345 107.8709 92.7791
KK/HlJ m 142.75 4.6963 151.9919 133.5081
LP/J f 88.7429 5.0206 98.6228 78.8629
LP/J m 105.725 4.6963 114.9669 96.4831
MRL/MpJ f 89.575 4.6963 98.8169 80.3331
MRL/MpJ m 94.2167 5.4228 104.8882 83.5451
NOD.B10Sn-H2b/J f 72.3429 5.0206 82.2228 62.4629
NOD.B10Sn-H2b/J m 109.475 4.6963 118.7169 100.2331
NZO/HlLtJ f 180.5714 5.0206 190.4514 170.6915
NZO/HlLtJ m 186.25 6.6416 199.32 173.18
NZW/LacJ f 126.375 4.6963 135.6169 117.1331
NZW/LacJ m 147.75 4.6963 156.9919 138.5081
P/J f 103.25 5.4228 113.9216 92.5784
P/J m 117.7143 5.0206 127.5942 107.8343
PL/J f 86.9571 5.0206 96.8371 77.0772
PL/J m 120.6667 5.4228 131.3382 109.9951
PWD/PhJ f 79.85 5.4228 90.5216 69.1784
PWD/PhJ m 87.025 6.6416 100.095 73.955
SJL/J f 41.22 5.9404 52.9101 29.5299
SJL/J m 82.9778 4.4277 91.6911 74.2645
SM/J f 77.8 5.0206 87.68 67.92
SM/J m 90.9571 5.0206 100.8371 81.0772
WSB/EiJ f 95.2875 4.6963 104.5294 86.0456
WSB/EiJ m 154.75 4.6963 163.9919 145.5081


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 110.6563 3.3208 117.1912 104.1213
A/J both 62.9 3.4373 69.6643 56.1357
BTBR T+ Itpr3tf/J both 95.3813 3.4373 102.1456 88.6169
BUB/BnJ both 63.5361 3.5004 70.4246 56.6476
C57BL/10J both 61.3375 3.4373 68.1018 54.5732
C57BL/6J both 75.5687 3.3208 82.1037 69.0338
C57BLKS/J both 58.1146 3.5869 65.1732 51.056
C57BR/cdJ both 87.7313 4.4964 96.5797 78.8828
C57L/J both 82.767 3.4373 89.5313 76.0026
CBA/J both 85.2437 3.3208 91.7787 78.7088
DBA/2J both 61.7464 3.695 69.0179 54.475
FVB/NJ both 121.7188 3.3208 128.2537 115.1838
KK/HlJ both 121.5375 3.0314 127.5031 115.5719
LP/J both 97.2339 3.4373 103.9983 90.4696
MRL/MpJ both 91.8958 3.5869 98.9544 84.8372
NOD.B10Sn-H2b/J both 90.9089 3.4373 97.6733 84.1446
NZO/HlLtJ both 183.4107 4.1628 191.6027 175.2187
NZW/LacJ both 137.0625 3.3208 143.5975 130.5275
P/J both 110.4821 3.695 117.7536 103.2107
PL/J both 103.8119 3.695 111.0834 96.5405
PWD/PhJ both 83.4375 4.2871 91.8741 75.0009
SJL/J both 62.0989 3.7045 69.389 54.8088
SM/J both 84.3786 3.5501 91.3648 77.3924
WSB/EiJ both 125.0188 3.3208 131.5537 118.4838




  GWAS USING LINEAR MIXED MODELS